Alpha-GPC 300mg Capsules 60 vegetarian capsules Acetyl-choline analogue Cognitive Support Bioavailable Source of Choline Supports Mental Acuity fssai approved GMP Certified, FDA Registered
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Alpha GPC 300mg Capsules 120 Capsules
COMPOSITION Each Capsule contains: L-alpha-glyceryl phosphoryl choline 300mg
THERAPEUTIC INDICATION Alpha-GPC is a compound made up of choline and glycerophosphate with neuroprotective activity. Alpha-GPC prevents cognitive decline, and increases attention and memory. Hence, it is a prescription medication for the treatment of Alzheimer’s disease.
DOSAGE AND ADMINISTRATION Alpha GPC is approximately 40% choline by weight, and as such 1,000 mg alpha-GPC confers about 400 mg of dietary choline. A standard dosage of alpha-GPC is 300-600 mg, according to the most common label doses.
This dose is following the study using alpha-GPC to enhance power output (600 mg) and the two studies noting an increase in growth hormone secretion and is likely a good dose to take for athletes.
For the usage of alpha-GPC in attenuating symptoms of cognitive decline, almost all studies use a dosage of 1,200 mg daily, divided into three doses of 400 mg. It is unsure how lower doses would benefit cognition, but the dose which is consistently associated with benefit .appears to be 1,200 mg.
Rat studies suggest that the effects of Alpha-GPC oral ingestion peak at 300-600 mg/kg, which is an estimated human dose of 48-96 mg/kg (and for a 150lb human, 3,272-6,545 mg daily).
For nootropic stack use, we recommend a dose of 300-600 mg to start out and then to increase from there if you decide you would benefit from more.
When taken at recommended dosages Alpha GPC is well tolerated. For most adults the range of acceptable dosage is relatively broad; a cumulative daily dosage of 300-1200 mg, when taken in one or two doses, is safe and efficient.
As is the case with all supplements, it is wise to start with the lowest possible effective dose and build gradually as needed.
Alpha GPC: Alpha GPC or Alpha-glycerophosphocholine (aGPC), as the name implies, is a choline-containing phospholipid isolated from soy. A wealth of research on this compound supports a role for enhancing cognitive function, increasing strength and stimulating the release of growth hormone.
Alpha GPC contains a lipid tail that permits the uptake and incorporation into neuronal cell membranes. The membrane-bound choline molecule supplies the necessary and rate limiting compound for acetylcholine neurotransmitter synthesis.
Though found both within the central and peripheral nervous system, cholinergic neurotransmission is the cornerstone for memory formation that takes place in a specialized brain region known as the hippocampus.
HEALTH BENEFITS:
1.In Alzheimer’s disease:
Developing research suggests that taking 1200 mg of alpha-GPC per day significantly improves thinking skills in Alzheimer’s patients after 3 to 6 months of treatment.
2.In Dementia:
Giving 1000 mg of alpha-GPC per day as a shot might improve symptoms of vascular (multi-infarct) dementia including behavior, mood, and thinking skills.
3.Stroke and “mini-stroke” (transient ischemic attack, TIA):
Stroke and TIA patients who receive alpha-GPC within 10 days after the stroke or TIA seem to have a better recovery. Early research suggests that people who get 1200 mg of alpha-GPC per day as a shot for 28 days, followed by 400 mg of alpha-GPC three times daily (1200 mg/day) by mouth for 6 months, recover more thinking skills and are better able to function.
4.In athletes:
Recent studies on aGPC have shown a potential benefit to athletic performance. A Japanese study investigated the effects of a single dose of aGCP on hormone release in healthy young males. Surprisingly a single dose of aGCP resulted in a substantial change in growth hormone release within one hour.
Mechanisms:
Dissociates into choline and the phospholipid glycerophosphate after ingestion
The most effective cholinergic in increasing choline levels in the brain
Choline is a nicotinic Acetylcholine receptor agonist
Increases potassium-invoked calcium release and dopamine release
Can increase growth hormone production
SAFETY RELATED INFORMATION:
Alpha-GPC seems to be safe when used appropriately. It can cause side effects in some people including heartburn, headache, insomnia, dizziness, skin rash, and confusion.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Not enough is known about the use of alpha-GPC during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Minor Interaction
Be watchful with this combination
Scopolamine interacts with ALPHA-GPC
Alpha-GPC increases a chemical in the brain called acetylcholine. Scopolamine blocks this same chemical. Alpha-GPC may decreases the benefits of scopolamine.
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MANUFACTURED BY: TAJ PHARMACEUTICALS LTD. Mumbai, India Unit No. 214.Old Bake House, Maharashtra chambers of Commerce Lane,Fort, Mumbai – 400001 at:Gujarat, INDIA.
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