Warfarin Tablets BP 1mg Technical Specification:

Product Name:
Warfarin Tablets BP 1mg
Brand Name:Generics
Strength:0.5mg, 1mg, 2mg, 3mg, 5mg
Dosage Form:Uncoated Tablets
Route of Administration:Via oral Route
Packing:10s, 30s, 100s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-coagulant (Blood thinner)
Indication: Warfarin is also used to treat or prevent venous thrombosis and pulmonary embolism. Warfarin is in a class of medications called anticoagulants (‘blood thinners’). It works by decreasing the clotting ability of the blood
Storage:Store at 25°C. Store in cool, dry & dark place. Protect from light.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Warfarin Tablets BP 1mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Warfarin Tablets BP 1mg
    Each uncoated tablet contains:
    Warfarin Sodium Clathrate BP
    Equivalent to
    Warfarin (as anhydrous) …………1mg
    Excipients………………………………q.s.

THERAPEUTIC INDICATIONS:

Warfarin is also used to treat or prevent venous thrombosis (swelling and blood clot in a vein) and pulmonary embolism (a blood clot in the lung).

Warfarin is in a class of medications called anticoagulants (‘blood thinners’). It works by decreasing the clotting ability of the blood.

There are most common indications for warfarin therapy are; atrial fibrillation (AF), venous thromboembolism (VTE), and prosthetic heart valves. Atrial fibrillation is probably the most common indication for warfarin therapy in our community.

CAUTION & WARNING:

CAUTION: Dispense in a tight, light-resistance container as defined in the USP, with a child-resistance closer.

Swallow whole do not chew or crush.

Not suitable for children under 5 years.

Dispense with medication guide.

For use under medical supervision only.

Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage:  Store at 25°C. Store in cool, dry & dark place. Protect from light.

Keep medicine out of reach of children.

Dosage:  As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharma is your trusted choice for Warfarin Tablets. With a commitment to quality, affordability, and patient well-being, we provide top-notch pharmaceutical solutions.

  • Quality Assurance: Taj Pharma upholds rigorous quality control standards, ensuring that every Warfarin Tablet meets stringent pharmaceutical criteria. Your safety and therapeutic efficacy are our utmost priorities.
  • Experience and Expertise: With a wealth of experience in the pharmaceutical industry, Taj Pharma has a proven track record of manufacturing and delivering high-quality medications, including Warfarin Tablets.
  • Affordability: We believe that essential medications like Warfarin should be accessible to all. Taj Pharma offers competitive pricing without compromising on quality, making Warfarin treatment affordable and within reach for a broader population.
  • Global Accessibility: Our products are available worldwide, ensuring that patients and healthcare providers have easy access to Warfarin Tablets, regardless of their geographic location.
  • Patient-Centric Approach: Taj Pharma values its patients and strives to provide exceptional service. We offer support, information, and resources to assist you throughout your Warfarin treatment journey.
  • Innovation: We invest in research and development to enhance our pharmaceutical offerings, ensuring that our Warfarin Tablets align with the latest advancements in medical science.
  • Compliance: Taj Pharma is committed to ethical practices and regulatory compliance. Our Warfarin Tablets adhere to all necessary regulatory requirements, guaranteeing their safety and effectiveness.

Choose Taj Pharma for your Warfarin Tablet needs and experience unparalleled quality, affordability, and a patient-centered approach. Your health and well-being are our top priorities, and we are dedicated to delivering pharmaceutical solutions you can trust.

What is Warfarin Tablets and its use?

Warfarin Tablets are a medication that contains the active ingredient warfarin. Warfarin is an anticoagulant, commonly referred to as a blood thinner. It is used for several medical purposes, primarily in the prevention and treatment of blood clots. Here’s a closer look at the uses of Warfarin Tablets:

  • Anticoagulation Therapy: Warfarin is frequently prescribed as an anticoagulant to prevent the formation of blood clots. It is used to reduce the risk of various conditions caused by blood clots, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke.
  • Atrial Fibrillation: Warfarin is often recommended for individuals with atrial fibrillation (a type of irregular heartbeat) to reduce the risk of stroke. In atrial fibrillation, blood can pool in the heart and form clots that can travel to the brain, causing a stroke.
  • Mechanical Heart Valves: Patients with mechanical heart valves are at an increased risk of blood clots forming on the valve. Warfarin is commonly prescribed to prevent these clots and their potential complications.
  • Treatment of Existing Blood Clots: In some cases, Warfarin may be used to treat existing blood clots, such as DVT or PE, to prevent the clot from growing or causing further complications.
  • Pulmonary Hypertension: Warfarin can be a part of the treatment plan for certain types of pulmonary hypertension, where blood clots may contribute to increased pressure in the pulmonary arteries.
  • Prevent Recurrence of Clots: After an initial episode of blood clot formation, Warfarin may be prescribed for a period to reduce the risk of recurrent clots.

Warfarin is a medication that requires careful monitoring and dose adjustment. The dosage is individualized for each patient based on factors like their medical condition, age, weight, and response to the medication. Regular blood tests, specifically the international normalized ratio (INR), are conducted to ensure that the dose is within the therapeutic range and that the blood is appropriately anticoagulated. Warfarin can interact with various foods, other medications, and alcohol, which can affect its effectiveness and safety. Patients taking Warfarin should closely follow their healthcare provider’s instructions and be diligent about monitoring and reporting any unusual bleeding or symptoms of clotting.

How Does Warfarin Tablets Work?

Warfarin Tablets work as anticoagulants, commonly referred to as blood thinners. Their primary mechanism of action involves interfering with the body’s natural blood clotting process. Here’s how Warfarin works:

  • Inhibition of Vitamin K: Warfarin inhibits the action of vitamin K, an essential nutrient required for the production of clotting factors in the liver. Clotting factors are proteins that play a crucial role in the blood clotting cascade.
  • Clotting Factor Production: Clotting factors are responsible for promoting the formation of blood clots when an injury or damage to a blood vessel occurs. By inhibiting vitamin K, Warfarin reduces the production of several clotting factors, particularly factors II, VII, IX, and X, which are dependent on vitamin K for their activation.
  • Prolonging Clotting Time: With a decrease in the levels of these clotting factors, Warfarin slows down the blood’s ability to clot. This means that it takes a longer time for the blood to form a clot in response to an injury or blood vessel damage.
  • Preventing Blood Clots: By prolonging the clotting time, Warfarin helps prevent the formation of abnormal and potentially harmful blood clots within blood vessels. This is particularly important in conditions like atrial fibrillation, deep vein thrombosis (DVT), pulmonary embolism (PE), and for individuals with mechanical heart valves who are at an increased risk of clot formation.
  • Individualized Dosage: Warfarin therapy requires careful monitoring and dose adjustment because individual responses to the medication can vary. Regular blood tests, such as the international normalized ratio (INR), are conducted to ensure that the blood’s clotting time remains within the desired therapeutic range.

Warfarin to maintain a consistent intake of the medication and to follow their healthcare provider’s instructions closely. Changes in diet, alcohol consumption, and other medications can affect Warfarin’s effectiveness and the risk of bleeding or clotting. Close monitoring and communication with healthcare providers are essential to ensure the safe and effective use of Warfarin Tablets.

Benefits of Warfarin Tablets:

  • Prevention of Blood Clots: The primary benefit of Warfarin Tablets is their effectiveness in preventing the formation of blood clots. This is especially important in conditions where clot formation can lead to serious health problems, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke.
  • Treatment of Existing Blood Clots: Warfarin is also used to treat existing blood clots, helping to prevent them from growing larger or causing further complications. This can be crucial for individuals who have already experienced a clot.
  • Management of Atrial Fibrillation: Warfarin is commonly prescribed to individuals with atrial fibrillation (AFib) to reduce the risk of stroke. AFib increases the risk of blood clots forming in the heart, which can then travel to the brain and cause a stroke.
  • Protection for Mechanical Heart Valve Recipients: Patients with mechanical heart valves are at an increased risk of blood clot formation on the valve, which can lead to valve dysfunction or embolism. Warfarin helps prevent these complications.
  • Prevention of Recurrent Clots: After an initial episode of blood clot formation, Warfarin may be used to reduce the risk of recurrent clots, providing ongoing protection.

Side Effects of Warfarin Tablets:

  • Bleeding: The most significant side effect of Warfarin is the increased risk of bleeding. This can manifest as nosebleeds, gum bleeding, easy bruising, or more serious bleeding into the digestive tract or brain. The risk of bleeding is closely monitored through regular blood tests.
  • Warfarin Skin Necrosis: In rare cases, Warfarin can lead to skin necrosis, where areas of the skin die due to impaired blood flow. This typically occurs early in the course of treatment.
  • Heparin-Induced Thrombocytopenia (HIT): Some individuals may develop an immune response to heparin, a medication often used in combination with Warfarin, which can lead to a decrease in platelet count and an increased risk of blood clots.
  • Hair Loss: Mild hair loss (alopecia) is a less common side effect of Warfarin, but it typically reverses when the medication is discontinued.
  • Nausea and Vomiting: Some people may experience mild gastrointestinal discomfort, including nausea and vomiting, when taking Warfarin.
  • Skin Rash: Skin reactions, including rash, itching, and redness, can occur but are relatively uncommon.

It’s essential to understand that the benefits of Warfarin in preventing or treating serious medical conditions often outweigh the potential risks of bleeding. However, close monitoring and communication with healthcare providers are essential to ensure that the medication is used safely and effectively. Patients on Warfarin should follow their healthcare provider’s instructions, attend regular check-ups, and report any unusual bleeding or symptoms promptly. Additionally, they should be aware of potential drug interactions and dietary considerations, as these can affect Warfarin’s effectiveness and safety.

Frequently asked questions (FAQs) about Warfarin Tablets:

  1. What is Warfarin?

Warfarin is an anticoagulant medication commonly referred to as a blood thinner. It is used to prevent and treat blood clots in various medical conditions.

  1. Why is Warfarin prescribed?

Warfarin is prescribed to prevent blood clots in conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AFib), mechanical heart valves, and more.

  1. How does Warfarin work?

Warfarin interferes with the body’s blood clotting process by inhibiting the action of vitamin K, which is necessary for the production of clotting factors in the blood.

  1. How is Warfarin dosage determined?

Warfarin dosage is individualized for each patient based on factors like their medical condition, age, weight, and response to the medication. Regular blood tests (INR) are used to monitor the effectiveness of the dosage.

  1. Can I eat foods with vitamin K while on Warfarin?

Yes, but it’s essential to maintain a consistent intake of foods with vitamin K while on Warfarin. Your healthcare provider can advise you on managing your diet.

  1. What are the side effects of Warfarin?

Common side effects include an increased risk of bleeding, easy bruising, nosebleeds, and gastrointestinal discomfort. Serious side effects are rare but can include skin necrosis and heparininduced thrombocytopenia (HIT).

  1. What should I do if I miss a dose of Warfarin?

If you miss a dose, take it as soon as you remember. However, if it’s close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

  1. Can I drink alcohol while taking Warfarin?

It’s best to avoid excessive alcohol consumption while on Warfarin, as alcohol can affect the medication’s effectiveness and increase the risk of bleeding.

  1. Can I take other medications with Warfarin?

Warfarin can interact with various medications, so it’s essential to inform your healthcare provider about all the medications, supplements, and herbal products you are taking.

  1. Can I engage in physical activities while on Warfarin?

Yes, but it’s important to discuss any planned physical activities, sports, or surgeries with your healthcare provider, as they may need to adjust your Warfarin dosage or provide specific guidance.

  1. Is Warfarin safe during pregnancy or breastfeeding?

Warfarin is generally not recommended during pregnancy due to potential risks to the fetus. It can be excreted in breast milk, so breastfeeding while on Warfarin should be discussed with a healthcare provider.

  1. How often should I have my INR (blood clotting) levels checked while on Warfarin?

The frequency of INR monitoring varies depending on your individual situation, but it is typically done regularly, especially during the early stages of treatment, to ensure that your blood clotting remains within the desired therapeutic range.

As Warfarin Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Warfarin Tablets  product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Warfarin Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Warfarin Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Warfarin Tablets BP 0.5mg
B) Warfarin Tablets BP 1mg
C) Warfarin Tablets BP 2mg
D) Warfarin Tablets BP 3mg
E) Warfarin Tablets BP 5mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Warfarin Tablets BP 0.5mg
Each uncoated tablet contains:
Warfarin Sodium Clathrate BP
Equivalent to
Warfarin (as anhydrous) …………0.5mg
Excipients………………………………q.s.

B) Warfarin Tablets BP 1mg
Each uncoated tablet contains:
Warfarin Sodium Clathrate BP
Equivalent to
Warfarin (as anhydrous) …………1mg
Excipients………………………………q.s.


C) Warfarin Tablets BP 2mg
Each uncoated tablet contains:
Warfarin Sodium Clathrate BP
Equivalent to
Warfarin (as anhydrous) …………2mg
Excipients………………………………q.s.

D) Warfarin Tablets BP 3mg
Each uncoated tablet contains:
Warfarin Sodium Clathrate BP
Equivalent to
Warfarin (as anhydrous) …………3mg
Excipients………………………………q.s.

E) Warfarin Tablets BP 5mg
Each uncoated tablet contains:
Warfarin Sodium Clathrate BP
Equivalent to
Warfarin (as anhydrous) …………5mg
Excipients………………………………q.s.

THERAPEUTIC INDICATIONS:

Warfarin is also used to treat or prevent venous thrombosis (swelling and blood clot in a vein) and pulmonary embolism (a blood clot in the lung).
Warfarin is in a class of medications called anticoagulants ('blood thinners'). It works by decreasing the clotting ability of the blood.
There are most common indications for warfarin therapy are; atrial fibrillation (AF), venous thromboembolism (VTE), and prosthetic heart valves. Atrial fibrillation is probably the most common indication for warfarin therapy in our community.

CAUTION & WARNING:

CAUTION: Dispense in a tight, light-resistance container as defined in the USP, with a child-resistance closer.
Swallow whole do not chew or crush.
Not suitable for children under 5 years.
Dispense with medication guide.
For use under medical supervision only.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store at 25°C.
Store in cool, dry & dark place.
Protect from light.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
Dosage: As directed by the Physician.