Vindesine Sulfate for Injection BP 1mg (Cilretta)

Vindesine Sulfate for Injection BP 1mg (Cilretta) Technical Specification:

GENERIC NAME OF THE MEDICINAL PRODUCT:

• Vindesine Sulfate for Injection BP 1mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Vindesine Sulfate for Injection BP 1mg
  Each ml contains:
  Vindesine Sulfate BP…………….….….1mg
  Sodium Chloride USP……………………9mg
  Benzyl Alcohol USP………………………0.9% v/v
  Water for Injection USP…….…………q.s.

THERAPEUTIC INDICATION:

Vindesine Sulfate is used to treat patients who have a cancer such as leukaemia, malignant melanoma (a type of skin cancer) or breast cancer.

DIRECTION OF USE:

For Intravenous infusion only.

Add sterile water for injection USP. Shake to dissolve, if product does not dissolve immediately allow to stand at room temperature until solution is obtained.

See the package insert for details.

CAUTION & WARNING:

CAUTION: This injection should not be used if it contains visible particulate matter after reconstitution. Fatal if given Intrathecally, for Intravenous use only.

CAUTION: This is a potent Cytotoxic agent. Use only after reading the directions on the pack insert.

WARNING: Cytotoxic Agent: To be sold by retail on the prescription of an Oncologist/ Cancer Hospital only.

CAUTION: Cytotoxic agent – Special Handling

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.

Discard Unused portion.

Keep out of the reach of the children.

STORAGE & DOSAGE:

Storage: Store between 2°C to 8°C in a refrigerator. Do not freeze. Protect rom light.

Dosage: As directed by an Oncologist.

Why Taj Pharmaceuticals?

Taj Pharma is your trusted source for Vindesine Sulfate for Injection. Our unwavering commitment to quality, affordability, and patient care makes us the preferred choice for this vital medication. Taj Pharma is your dependable partner for Vindesine Sulfate for Injection, and here’s why you should choose us for your healthcare needs:

• Quality Assurance: At Taj Pharma, quality is our top priority. We adhere to stringent quality control measures throughout the manufacturing process to ensure that every vial of Vindesine Sulfate meets the highest industry standards. You can trust the purity, potency, and safety of our medication.
• Affordable Healthcare: We understand the financial challenges that can come with critical medical treatments. That’s why Taj Pharma is dedicated to offering competitive pricing for Vindesine Sulfate for Injection, making it accessible to patients without compromising on quality.
• Patient-Centric Approach: Taj Pharma is committed to patient well-being. Our knowledgeable and empathetic customer support team is here to assist you at every step, providing information, answering your questions, and ensuring a seamless experience from order to delivery. We prioritize your health and convenience.

When it comes to Vindesine Sulfate for Injection, Taj Pharma combines pharmaceutical excellence with a commitment to affordability and patient care. Trust us as your reliable source for this vital medication.

What is Vindesine Sulfate for Injection and its use?

Vindesine Sulfate for Injection is a medication used in the treatment of various types of cancer. It belongs to a class of drugs known as vinca alkaloids, which work by interfering with the growth and spread of cancer cells. Here’s an overview of its use:

Indications and Uses:

• Cancer Treatment: Vindesine Sulfate is primarily used in the treatment of certain types of cancer, including:
• Hodgkin’s Lymphoma: It can be a part of combination chemotherapy regimens for treating Hodgkin’s lymphoma, a cancer of the lymphatic system.
• Non-Hodgkin’s Lymphoma: Vindesine Sulfate may also be used in the treatment of non-Hodgkin’s lymphoma, which is another form of lymphatic system cancer.
• Lung Cancer: It is used in the treatment of small cell lung cancer, particularly in combination with other chemotherapy drugs.
• Breast Cancer: Vindesine Sulfate may be part of the treatment regimen for advanced or metastatic breast cancer.
• Other Cancers: In some cases, it may be considered for the treatment of other cancers, such as bladder cancer, testicular cancer, and neuroblastoma.

The use of Vindesine Sulfate for Injection is determined by oncologists and healthcare professionals based on the specific type and stage of cancer, as well as the patient’s overall health and treatment plan. It is typically administered by healthcare providers through intravenous (IV) infusion. Due to its potent anti-cancer properties, close monitoring and expert medical supervision are essential during its use to manage potential side effects and ensure the best possible outcome for the patient.

How does Vindesine Sulfate for Injection Work?

Vindesine Sulfate for Injection works as an anticancer medication by interfering with the growth and division of cancer cells. It belongs to a class of drugs called vinca alkaloids, and its mechanism of action involves several key steps:

• Microtubule Disruption: Inside cells, there are structures called microtubules that play a crucial role in cell division (mitosis). Microtubules are like the cell’s “skeleton,” providing structural support and serving as tracks along which cellular components move during cell division. They are essential for the separation of chromosomes during cell replication.
• Binding to Tubulin: Vindesine sulfate specifically binds to tubulin, which is a protein that makes up microtubules. By attaching to tubulin, vindesine disrupts the normal formation and function of microtubules.
• Inhibition of Mitosis: When microtubules are disrupted by vindesine, the cancer cells are unable to properly organize and separate their chromosomes during cell division. This interference with mitosis prevents cancer cells from replicating and dividing.
• Cell Death: The disruption of microtubules and the failure of cell division ultimately lead to the death of cancer cells. They are unable to proliferate and form tumors.

Vindesine Sulfate for Injection interferes with the structural components necessary for cell division, causing the arrest of cancer cell growth and, in some cases, leading to cell death. This mechanism of action makes it an effective treatment for various types of cancer, particularly those where uncontrolled cell division is a hallmark of the disease. It is important to note that the use of Vindesine Sulfate requires careful medical supervision and monitoring due to its potential side effects and the need to tailor treatment to the specific type and stage of cancer.

Benefits of Vindesine Sulfate for Injection:

• Effective Cancer Treatment: Vindesine Sulfate is used in the treatment of various types of cancer, including Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, small cell lung cancer, breast cancer, and others. It can be an essential component of chemotherapy regimens, helping to slow down or stop the growth of cancer cells and improve the patient’s prognosis.
• Combination Therapy: Vindesine Sulfate is often used in combination with other chemotherapy drugs to enhance treatment effectiveness. This combination approach can target cancer from multiple angles, increasing the chances of a positive response.

Common Side Effects of Vindesine Sulfate for Injection:

• Nausea and Vomiting: Nausea and vomiting are common side effects of chemotherapy, including Vindesine Sulfate. Medications are often prescribed to help manage these symptoms.
• Bone Marrow Suppression: Vindesine Sulfate can suppress the bone marrow’s ability to produce blood cells, leading to an increased risk of anemia (low red blood cell count), leukopenia (low white blood cell count), and thrombocytopenia (low platelet count). This can result in fatigue, increased susceptibility to infections, and a higher risk of bleeding.
• Peripheral Neuropathy: Some individuals may experience peripheral neuropathy, characterized by tingling, numbness, or pain in the hands and feet. This side effect is usually reversible but may persist or worsen with continued use.
• Hair Loss: Hair loss, or alopecia, is a common side effect of chemotherapy, which can include Vindesine Sulfate. Hair typically grows back once treatment is completed.
• Fatigue: Chemotherapy often leads to fatigue and general weakness. Rest and a balanced diet can help manage this side effect.

Less Common but Serious Side Effects:

• Allergic Reactions: Although rare, allergic reactions can occur. Signs of an allergic reaction may include hives, difficulty breathing, swelling of the face or throat, and severe dizziness. Seek immediate medical attention if these symptoms occur.
• Bone Marrow Depression: In some cases, Vindesine Sulfate can cause severe bone marrow depression, leading to life-threatening complications. Regular blood tests are done to monitor blood cell counts during treatment.
• Increased Risk of Infections: A weakened immune system due to bone marrow suppression can make patients more susceptible to infections. Any signs of infection, such as fever, should be promptly reported to a healthcare provider.

The benefits of Vindesine Sulfate treatment in fighting cancer often outweigh the potential side effects. Healthcare providers carefully assess the risks and benefits for each patient and may provide supportive care to manage side effects and optimize treatment outcomes. It’s important for patients to communicate openly with their healthcare team about any side effects or concerns they may have during treatment.

Frequently asked questions (FAQs) about Vindesine Sulfate for Injection:

1. What is Vindesine Sulfate for Injection used to treat?

Vindesine Sulfate for Injection is used to treat various types of cancer, including Hodgkin’s lymphoma, no Hodgkin’s lymphoma, small cell lung cancer, and breast cancer, among others.

2. How is Vindesine Sulfate for Injection administered?

It is typically administered through intravenous (IV) infusion by healthcare professionals in a clinical setting.

3. What is the mechanism of action of Vindesine Sulfate for Injection?

Vindesine Sulfate interferes with the growth and division of cancer cells by binding to tubulin, disrupting microtubule function, and preventing proper cell division.

4. What are the common side effects of Vindesine Sulfate for Injection?

Common side effects may include nausea, vomiting, bone marrow suppression (anemia, leukopenia, thrombocytopenia), peripheral neuropathy, and hair loss.

5. How long does a course of Vindesine Sulfate treatment typically last?

The duration of treatment varies depending on the type and stage of cancer, as well as the individual patient’s response. Treatment plans are determined by oncologists.

6. Are there any special precautions to take while receiving Vindesine Sulfate treatment?

Patients should take precautions to minimize the risk of infection, as their immune system may be weakened. Regular blood tests to monitor blood cell counts are often required.

7. Can I continue with normal daily activities while on Vindesine Sulfate treatment?

Fatigue is a common side effect, so it’s essential to listen to your body and get adequate rest. Activities should be discussed with your healthcare provider based on your individual condition.

8. Is Vindesine Sulfate for Injection safe during pregnancy or while breastfeeding?

It is generally not recommended during pregnancy due to potential harm to the developing fetus. Patients should discuss family planning and contraception with their healthcare provider. Breastfeeding should also be avoided during treatment.

9. What should I do if I miss a scheduled Vindesine Sulfate infusion?

If a scheduled infusion is missed, it’s crucial to contact your healthcare provider immediately to reschedule and discuss any potential impact on your treatment plan.

10. Can I take other medications or supplements while on Vindesine Sulfate treatment?

Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as some may interact with Vindesine Sulfate. Your healthcare team will provide guidance on any necessary adjustments.

As Vindesine Sulfate for Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Vindesine Sulfate for Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Vindesine Sulfate for Injection Regulatory Documents:

• Certificate of Analysis (COA)
• Method of Analysis (MOA)
• Stability Data (Accelerated stability / Long-term stability / Zone 4b)
• CTD Dossier / ACTD Dossiers / eCTD Dossiers
• Certificate of Pharmaceuticals Product (COPP)
• Free Sale Certificate (FSC)

Contact the most reliable manufacturer of  Vindesine Sulfate for Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274