Vinblastine Sulphate Injection 1mg/ml (10mg/10ml) (Veluterin)

Vinblastine Sulphate Injection 1mg/ml (10mg/10ml) (Veluterin) Technical Specification:    

GENERIC NAME OF THE MEDICINAL PRODUCT:

• Vinblastine Sulphate Injection 1mg/ml (10mg/10ml)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Vinblastine Sulphate Injection 1mg/ml (10mg/10ml)
  Each ml contains
  Vinblastine Sulphate USP………..1mg
  Sodium Chloride USP………………9mg
  Benzyl Alcohol USP………………….0.9% v/v
  Water for Injection USP………….q.s.

THERAPEUTIC INDICATION:

Vinblastine Sulphate to treat a number of types of cancer. This includes Hodgkin’s lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer.

PACKING:

1mg/ml (10mg/10ml)

DIRECTION OF USE:

For I.V. use only

See package insert for complete prescribing information.

CAUTION & WARNING:

CAUTION: This injection should not be used if it contains visible particulate. Fatal if given Intrathecally for Intravenous use only.
CAUTION: Cytotoxic agent – Special Handling.
CAUTION: This is a potent Cytotoxic agent. Use only after reading the directions on the pack insert.
WARNING: Cytotoxic Agent – To be sold by retail on the prescription of an Oncologist/ Cancer Hospital/ Institution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.
Discard any unused solution.
Contains no antibacterial preservatives.
Keep out of reach of children.

STORAGE & DOSAGE:

Storage: Store between 2°C to 8°C (36° F to 46° F) in a refrigerator.
Do not freeze. Protect from light.
Dosage: As directed by the Oncologist.

Why Taj pharmaceuticals?

Taj Pharmaceuticals is renowned for its unwavering commitment to pharmaceutical excellence, and this dedication extends to Vinblastine Sulphate Injection, a crucial component in the battle against cancer. With a legacy of pioneering research and a commitment to setting the highest industry standards, Taj Pharmaceuticals ensures that individuals facing cancer have access to not only effective treatments but also hope for a brighter future. One of the hallmarks of Taj Pharmaceuticals is its state-of-the-art manufacturing facilities and rigorous quality control measures. Vinblastine Sulphate Injection is no exception, undergoing stringent quality checks to guarantee that each vial meets the exacting specifications necessary to combat cancer effectively. This commitment to quality is a testament to Taj Pharmaceuticals’ dedication to patient well-being and safety. At Taj Pharmaceuticals, the mission transcends medication production; it is about improving lives and advancing the frontiers of cancer care. Vinblastine Sulphate Injection embodies this commitment, offering a ray of hope to cancer patients around the world. Taj Pharmaceuticals’ global presence ensures that individuals and healthcare providers have access to this vital chemotherapy medication, underscoring the company’s belief that quality healthcare should be accessible to all, regardless of geography. In choosing Taj Pharmaceuticals for Vinblastine Sulphate Injection, you are not merely selecting a medication; you are partnering with a company that places your health and recovery at the forefront. Taj Pharmaceuticals is honored to be your pharmaceutical provider, supporting you in your journey toward renewed health, resilience, and a future free from the burden of cancer.

What is Vinblastine Sulphate Injection and its uses:

Vinblastine Sulphate Injection: A Weapon Against Cancer

Vinblastine Sulphate Injection, derived from the periwinkle plant, is a potent weapon in the battle against cancer. Administered intravenously under the care of healthcare professionals, this medication belongs to the class of vinca alkaloids and is renowned for its efficacy in cancer therapy.

At the forefront of its uses is the treatment of various cancers. Vinblastine Sulphate is particularly valuable in addressing blood-related cancers such as Hodgkin’s lymphoma and non-Hodgkin’s lymphoma. It plays a pivotal role in slowing or halting the growth of cancer cells, offering patients hope in their fight against these diseases.

In the realm of solid tumors, Vinblastine Sulphate Injection shines as a treatment for cancers like testicular, breast, and lung cancer. When used in combination with other chemotherapy agents, it proves effective in reducing tumor sizes and managing cancer progression.

For patients with testicular cancer, especially in its early stages or when it has metastasized, Vinblastine Sulphate is a key component in the treatment arsenal. In the case of breast cancer, it may help control the disease’s advancement, offering relief from symptoms. Similarly, for individuals with lung cancer, particularly the small cell type, this medication slows down tumor growth by hindering the rapid division of cancer cells.

Vinblastine Sulphate Injection is a valuable tool not limited to these cancers alone; it may be considered for various other cancer types depending on specific disease characteristics and the comprehensive treatment plan crafted by oncologists.

It’s imperative to recognize that this medication is administered with precision in a clinical setting under the watchful eye of experienced healthcare providers. The dosage and treatment duration are meticulously determined based on the cancer’s type, stage, and the patient’s overall health. While Vinblastine Sulphate can be effective in fighting cancer, it may also entail side effects, which are diligently monitored and managed by the healthcare team. Patients should engage in open dialogue with their oncologist to gain a thorough understanding of their treatment plan and potential side effects, ensuring the best possible outcome in their cancer journey.

How do Vinblastine Sulphate Injection work?

The Mechanism of Vinblastine Sulphate Injection Against Cancer

Vinblastine Sulphate Injection represents a formidable weapon in the fight against cancer, operating through a sophisticated mechanism designed to disrupt the growth and division of cancer cells. At its core, this medication falls under the category of mitotic inhibitors, and its primary objective is to impede the uncontrolled proliferation of cancer cells.

A pivotal aspect of its action centers on the interference with a fundamental cellular process called mitosis. During mitosis, cells rely on intricate structures known as microtubules to ensure the orderly separation of chromosomes. Vinblastine Sulphate Injection steps in at this crucial juncture, undermining the formation and stability of these microtubules. As a result, the cancer cells are unable to establish a robust framework for the proper segregation of chromosomes.

The consequence of this disruption is profound. Cancer cells, caught in a state of arrested mitosis, find themselves unable to complete the process of cell division. This effectively puts the brakes on their rapid proliferation, preventing the creation of new daughter cells. Moreover, these halted cancer cells often undergo a self-destructive process known as apoptosis, leading to their demise. This dual action—mitotic arrest and programmed cell death—results in a reduction in tumor size and a halt in its growth.

Vinblastine Sulphate Injection may also exhibit anti-angiogenic properties. It hampers the formation of new blood vessels, a process called angiogenesis, which is crucial for tumor nourishment and expansion. By impeding angiogenesis, it further limits the tumor’s ability to thrive and spread.

This medication is frequently employed in combination with other chemotherapy agents, as this strategy can enhance its effectiveness. By targeting various stages of the cell cycle, combination therapies offer a comprehensive attack on cancer cells, making it more challenging for them to develop resistance.

It is important to recognize that while Vinblastine Sulphate Injection is highly effective against rapidly dividing cancer cells, it may also impact some healthy cells in the body, leading to side effects. These side effects are diligently monitored and managed by healthcare professionals during treatment to ensure the best possible outcome for cancer patients. The decision to use Vinblastine Sulphate and its specific dosage are tailored to the type and stage of cancer, as well as the patient’s overall health, under the expert guidance of oncologists.

Benefits of Vinblastine Sulphate Injection:

Vinblastine Sulphate Injection is a vital tool in the battle against cancer, offering several key benefits. Foremost, it stands as a highly effective cancer treatment, demonstrating remarkable efficacy in various cancer types, including Hodgkin’s and non-Hodgkin’s lymphomas, testicular cancer, breast cancer, and lung cancer. Its mechanism of action, which disrupts the division of cancer cells, plays a pivotal role in slowing or halting the progression of these diseases.

In the realm of cancer therapy, combination treatments are frequently employed for enhanced effectiveness. Vinblastine Sulphate Injection shines as an essential component of combination therapy, where multiple drugs target different stages of the cell cycle. This comprehensive approach not only bolsters the medication’s efficacy but also reduces the risk of cancer cells developing resistance to treatment.

Another notable benefit lies in its potential to inhibit angiogenesis, the formation of new blood vessels. This process is crucial for tumor growth and metastasis. Vinblastine Sulphate’s ability to impede angiogenesis restricts the tumor’s capacity to flourish and spread, contributing significantly to the success of cancer treatment.

Side Effects of Vinblastine Sulphate Injection:

Despite its effectiveness, Vinblastine Sulphate Injection may entail some side effects that warrant attention and management. One primary side effect is bone marrow suppression, which can result in reduced production of blood cells. This can lead to complications such as anemia, thrombocytopenia, and neutropenia, with associated symptoms like fatigue, increased susceptibility to infections, and bleeding tendencies.

Gastrointestinal discomfort is another common side effect, encompassing symptoms like nausea, vomiting, diarrhea, and constipation. While these symptoms are often manageable with supportive care and medication, they can impact the patient’s quality of life during treatment.

Some individuals may experience peripheral neuropathy, characterized by tingling or numbness in the hands and feet. Fortunately, this side effect is usually reversible once treatment is completed.

Hair loss (alopecia) is a temporary but emotionally challenging side effect that many cancer patients encounter during chemotherapy, including Vinblastine Sulphate Injection.

Additionally, patients may notice pain, redness, or irritation at the injection site. Strategies such as rotating injection sites and using warm compresses can help alleviate this discomfort.

Fatigue, a common consequence of both cancer and its treatment, can be significant and impact daily activities.

While allergic reactions to Vinblastine Sulphate Injection are rare, they can be serious and include symptoms like difficulty breathing, swelling, or skin rash. Immediate medical attention is essential if an allergic reaction is suspected.

Lastly, this medication may affect liver and kidney function in some cases, leading to abnormal blood test results. Close monitoring is essential during treatment to address any emerging issues promptly.

It’s crucial to recognize that the occurrence and severity of these side effects can vary among individuals. Healthcare providers carefully weigh the benefits of Vinblastine Sulphate Injection against the potential risks when prescribing it, and managing and minimizing side effects is an integral part of the overall cancer treatment plan. Open communication with the healthcare team ensures that patients receive the best possible care and support during their cancer journey.

Frequently Asked Questions About Vinblastine Sulphate Injection:

Certainly, here are some frequently asked questions (FAQs) about Vinblastine Sulphate Injection:

1. What is Vinblastine Sulphate Injection used for?

Vinblastine Sulphate Injection is primarily used for the treatment of various cancers, including Hodgkin’s and non-Hodgkin’s lymphomas, testicular cancer, breast cancer, and lung cancer. It is administered intravenously as part of cancer therapy.

2. How does Vinblastine Sulphate Injection work against cancer?

Vinblastine Sulphate Injection is a mitotic inhibitor that disrupts the division of cancer cells, leading to their arrest in the cell cycle and eventual cell death. It also exhibits antiangiogenic properties by inhibiting the formation of new blood vessels crucial for tumor growth.

3. Is Vinblastine Sulphate Injection used alone or in combination with other treatments?

Vinblastine Sulphate Injection is often used in combination with other chemotherapy agents. Combination therapy enhances its effectiveness and reduces the risk of cancer cells developing resistance.

4. What are the common side effects of Vinblastine Sulphate Injection?

Common side effects include bone marrow suppression (leading to anemia, thrombocytopenia, and neutropenia), gastrointestinal issues (nausea, vomiting, diarrhea, constipation), peripheral neuropathy, hair loss (alopecia), injection site reactions, fatigue, and potential liver and kidney function changes. Allergic reactions are rare but possible.

5. How is the dosage of Vinblastine Sulphate Injection determined?

The dosage and treatment plan with Vinblastine Sulphate Injection are determined by healthcare professionals based on the type and stage of cancer, as well as the patient’s overall health. Close monitoring is crucial throughout the treatment.

6. Are there any dietary restrictions while receiving Vinblastine Sulphate Injection?

There are generally no specific dietary restrictions, but maintaining good nutrition and hydration is important to manage gastrointestinal side effects and support overall wellbeing during treatment.

7. Can Vinblastine Sulphate Injection be administered at home, or is it given in a clinical setting?

Vinblastine Sulphate Injection is typically administered in a clinical setting by healthcare professionals experienced in chemotherapy. They ensure precise dosing and monitor for potential side effects.

8. Is it safe to become pregnant or father a child while receiving Vinblastine Sulphate Injection?

Vinblastine Sulphate Injection can harm an unborn baby, so it is crucial to discuss family planning and contraception options with your healthcare provider before starting treatment. Men should also use effective contraception during and after treatment.

9. What should I do if I miss a dose of Vinblastine Sulphate Injection?

Missing a dose of Vinblastine Sulphate Injection can affect treatment effectiveness. If you miss a dose or have questions about your treatment schedule, consult your healthcare provider immediately for guidance.

10. How long will I receive Vinblastine Sulphate Injection treatment?

The duration of treatment with Vinblastine Sulphate Injection depends on the type and stage of cancer, as well as how well the patient responds to therapy. Treatment plans are individualized, and your healthcare provider will provide guidance on the expected duration.

These FAQs provide important information about Vinblastine Sulphate Injection, but patients should consult their healthcare providers for personalized guidance and to address specific questions or concerns related to their treatment.

As Vinblastine Sulphate Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Vinblastine Sulphate Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Vinblastine Sulphate Injection Regulatory Documents:

• Certificate of Analysis (COA)
• Method of Analysis (MOA)
• Stability Data (Accelerated stability / Long-term stability / Zone 4b)
• CTD Dossier / ACTD Dossiers / eCTD Dossiers
• Certificate of Pharmaceuticals Product (COPP)
• Free Sale Certificate (FSC)

Contact the most reliable manufacturer of  Vinblastine Sulphate Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274