Valsartan and Hydrochlorothiazide Tablets USP 160mg+12.5mg

How does Valsartan and Hydrochlorothiazide Tablets work?

Valsartan and Hydrochlorothiazide Tablets are designed to effectively lower high blood pressure through a combination of two active ingredients, each with distinct mechanisms of action. This medication is prescribed to individuals with hypertension, a condition characterized by elevated blood pressure levels that can lead to serious health complications.

The first active component, Valsartan, belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). Its primary function is to counteract the effects of angiotensin II, a hormone that causes blood vessels to constrict, thereby increasing blood pressure. Valsartan works by blocking angiotensin II receptors in blood vessel walls. By doing so, it prevents angiotensin II from inducing vessel constriction. As a result, blood vessels relax and widen, reducing resistance to blood flow. This relaxation leads to a decrease in blood pressure, relieving strain on the heart.

The second component, Hydrochlorothiazide, is classified as a diuretic or “water pill.” It primarily acts on the kidneys, increasing the excretion of sodium and water in urine. By promoting higher urine production, Hydrochlorothiazide reduces the volume of fluid within the bloodstream. With less fluid in the blood vessels, there is reduced pressure exerted on the vessel walls, contributing to a decrease in blood pressure. Moreover, this diuretic helps counteract the effects of sodium retention, a common factor in hypertension.

In combination, Valsartan and Hydrochlorothiazide create a synergistic effect. Valsartan relaxes blood vessels, diminishing the force of blood against vessel walls, while Hydrochlorothiazide aids in the removal of excess fluid and sodium from the body, further lowering blood volume and vessel pressure. This dual-action approach is often recommended when single medications alone may not suffice to effectively manage high blood pressure. By targeting different aspects of blood pressure regulation, Valsartan and Hydrochlorothiazide Tablets offer an effective solution for hypertension management, reducing the risk of associated health complications.

Benefits of Valsartan and Hydrochlorothiazide Tablets:

Valsartan and Hydrochlorothiazide Tablets offer several key benefits for individuals dealing with hypertension. Firstly, they are highly effective in managing high blood pressure, ensuring that patients can maintain healthy blood pressure levels. This combination medication combines the effects of an angiotensin II receptor blocker (Valsartan) and a diuretic (Hydrochlorothiazide) to provide a synergistic impact, enhancing overall blood pressure control.

Another significant advantage is the reduced risk of serious cardiovascular events. Lowering blood pressure through the use of these tablets can significantly diminish the likelihood of life-threatening conditions like heart attacks, strokes, and heart failure. This makes them a crucial tool in preventing such critical health issues and improving overall cardiovascular health.

Furthermore, the convenience of combination therapy is a notable benefit. Rather than having to manage multiple medications separately, patients can simplify their treatment regimen by taking a single tablet. This not only makes it more straightforward but also improves adherence to the prescribed treatment plan.

Side Effects of Valsartan and Hydrochlorothiazide Tablets:

Despite their many advantages, Valsartan and Hydrochlorothiazide Tablets can potentially lead to side effects that patients should be aware of. These side effects include the possibility of low blood pressure (hypotension), which may manifest as dizziness, lightheadedness, or fainting in some individuals.

The diuretic component, Hydrochlorothiazide, can contribute to dehydration and electrolyte imbalances due to increased urine production. This may lead to symptoms like muscle cramps, weakness, and irregular heartbeat. Kidney function changes and increased blood uric acid levels are also potential side effects, particularly concerning for those with pre-existing kidney conditions or gout.

In rare cases, allergic reactions may occur, characterized by symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Additionally, some common side effects can include headaches, upset stomach, diarrhea, and fluctuations in blood glucose levels.

Patients taking Valsartan and Hydrochlorothiazide Tablets should maintain regular communication with their healthcare provider, who can monitor their progress and adjust the treatment plan if necessary. Prompt reporting of any concerning or severe side effects is essential to ensure optimal blood pressure control while minimizing side effects. Patients should always adhere to their healthcare provider’s guidance for the safe and effective use of this medication.

Frequently Asked Questions About Valsartan and Hydrochlorothiazide Tablets:

Certainly, here are some frequently asked questions (FAQs) about Valsartan and Hydrochlorothiazide Tablets:

1. What are Valsartan and Hydrochlorothiazide Tablets used for?

Valsartan and Hydrochlorothiazide Tablets are primarily used to treat high blood pressure, also known as hypertension. They are prescribed to help lower blood pressure and reduce the risk of related cardiovascular complications.

2. How do Valsartan and Hydrochlorothiazide Tablets work?

Valsartan relaxes blood vessels, reducing resistance to blood flow, while Hydrochlorothiazide acts as a diuretic, increasing urine production to remove excess fluid and sodium from the body. Together, they lower blood pressure through a dual action approach.

3. Can I take Valsartan and Hydrochlorothiazide Tablets if I have kidney problems?

It depends on the severity of your kidney condition. Your healthcare provider will assess your kidney function and determine if this medication is suitable for you. In some cases, dose adjustments or alternative treatments may be recommended.

4. Are there any dietary restrictions while taking these tablets?

It’s advisable to discuss dietary considerations with your healthcare provider, especially regarding salt (sodium) intake. Reducing high sodium foods can complement the medication’s effects in managing blood pressure.

5. What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take two doses to make up for a missed one.

6. Are there potential side effects of Valsartan and Hydrochlorothiazide Tablets?

Yes, like all medications, Valsartan and Hydrochlorothiazide Tablets can have side effects. Common ones include dizziness, headache, upset stomach, and increased urination. More serious side effects may include low blood pressure, electrolyte imbalances, and kidney function changes. It’s crucial to report any unusual or severe side effects to your healthcare provider.

7. Can I drink alcohol while taking these tablets?

Alcohol can interact with this medication and potentially exacerbate its side effects, including dizziness and low blood pressure. It’s advisable to limit alcohol consumption or consult with your healthcare provider about alcohol use while on this medication.

8. Is it safe to take other medications or supplements along with Valsartan and Hydrochlorothiazide Tablets?

Always inform your healthcare provider about all the medications, supplements, and over-the-counter drugs you are taking. Some medications and supplements may interact with Valsartan and Hydrochlorothiazide, so your provider can assess potential interactions and adjust your treatment plan accordingly.

9. How long should I continue taking Valsartan and Hydrochlorothiazide Tablets?

The duration of treatment depends on your specific condition and response to the medication. Typically, hypertension is a chronic condition, and many individuals need to take medication long-term. Your healthcare provider will guide you on the appropriate duration of treatment.

10. Can I stop taking the medication if my blood pressure improves?

It’s essential to follow your healthcare provider’s guidance and not discontinue the medication without their approval. Stopping treatment abruptly can lead to a sudden increase in blood pressure and potential health risks. Any changes to your medication regimen should be discussed with your healthcare provider.

As Valsartan and Hydrochlorothiazide Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Valsartan and Hydrochlorothiazide Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Valsartan and Hydrochlorothiazide Tablets Regulatory Documents:

• Certificate of Analysis (COA)
• Method of Analysis (MOA)
• Stability Data (Accelerated stability / Long-term stability / Zone 4b)
• CTD Dossier / ACTD Dossiers / eCTD Dossiers
• Certificate of Pharmaceuticals Product (COPP)
• Free Sale Certificate (FSC)

Contact the most reliable manufacturer of Valsartan and Hydrochlorothiazide Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
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