Trimethoprim Tablets 100mg Technical Specification:

Product Name:Trimethoprim Tablets 100mg
Brand Name:Generic
Strength:100mg, 200mg
Dosage Form:Tablets (Un-coated)
Route of Administration:Via Oral Route
Packing:10s, 30s, 50s, 100s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antibiotic
Indication: Trimethoprim Tablets belong to a group of medicines known as antibacterials. They are used to kill a wide range of bacteria that cause infections in your body, primarily urinary and respiratory tract infections. This medicine can also be used for prevention of recurrent urinary tract infections.
Storage:Store at 20° to 25°C (68° to 77°F). Do not store in the bathroom.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Trimethoprim Tablets 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Trimethoprim Tablets 100mg
    Each Un-coated tablet contains:
    Trimethoprim BP ………………100mg
    Excipients……………………………. q.s.

THERAPEUTIC INDICATIONS:

Trimethoprim Tablets belong to a group of medicines known as antibacterials. They are used to kill a wide range of bacteria that cause infections in your body, primarily urinary and respiratory tract infections. This medicine can also be used for prevention of recurrent urinary tract infections.

It is particularly useful in women with a simple UTI and short 3 days course usually eradicates the infection completely.

CAUTION & WARNING:

CAUTION:  SWALLOW WHOLE DO NOT CHEW OR CRUSH

A BROAD-SPECTRUM antibiotic that is particularly effective for use in cystitis and urinary track infections (Utis)

Increasing your water intake also helps to flush the bacteria out.

****Oral Tablet.

Read enclosed leaflet before use.

Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

Prescription-only medication for treat cystitis/UTI

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F). Do not store in the bathroom.

Dosage:
Recommended dose for cystitis: –
One tablet to be taken twice a day (every 12 hours) for 3 days with a full glass of water.

Usual adult dose for Urinary Track Infection:
100mg orally every 12 hours or 200mg orally every 24 hours.

Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

When it comes to Trimethoprim Tablets, Taj Pharma stands out as your reliable partner. With a history of unwavering commitment to pharmaceutical excellence, Taj Pharma has become the preferred choice for those seeking top-quality medications. Our Trimethoprim Tablets are meticulously crafted to meet the highest industry standards, ensuring efficacy and safety for patients. At Taj Pharma, we prioritize your health and well-being. Our dedication to research and development guarantees that you receive the latest advancements in medication technology. Whether you’re a healthcare professional or a patient, you can trust Taj Pharma’s Trimethoprim Tablets to deliver consistent results and relief from bacterial infections. Join the countless individuals and healthcare providers who rely on Taj Pharma for their pharmaceutical needs. Choose Taj Pharma for Trimethoprim Tablets, and experience the difference of pharmaceutical excellence. Your health deserves nothing less than the best, and Taj Pharma delivers just that.

What is Trimethoprim Tablets and its use?

Trimethoprim tablets are a type of medication that contains the active ingredient trimethoprim. Trimethoprim is an antibiotic commonly used to treat various bacterial infections. It belongs to a class of antibiotics known as dihydrofolate reductase inhibitors. Here’s an overview of its uses and how it works:

  • Bacterial Infections: Trimethoprim is primarily prescribed to treat bacterial infections. It is effective against a wide range of bacteria, including Escherichia coli (E. coli), Klebsiella, Proteus, and certain strains of Streptococcus and Staphylococcus. Trimethoprim works by inhibiting the production of a crucial component needed for bacterial DNA synthesis, which ultimately prevents the bacteria from multiplying and spreading.
  • Urinary Tract Infections (UTIs): One of the most common uses of trimethoprim is in the treatment of uncomplicated urinary tract infections. It can help alleviate symptoms like frequent urination, pain, and burning sensation during urination, and lower abdominal discomfort caused by UTIs.
  • Respiratory Infections: Trimethoprim may also be prescribed to treat respiratory tract infections, such as bronchitis and pneumonia, when the causative agent is susceptible to this antibiotic.
  • Traveler’s Diarrhea: In some cases, trimethoprim may be used to treat traveler’s diarrhea caused by certain bacterial infections.
  • Other Infections: Trimethoprim may be considered for other bacterial infections, as determined by a healthcare provider.

Trimethoprim is usually not effective against viral infections like the common cold or the flu. It should only be used as prescribed by a healthcare professional for bacterial infections. Additionally, as with any medication, it’s crucial to complete the full course of treatment even if you start feeling better before the medication is finished to ensure that all the bacteria causing the infection are eradicated.

How does Trimethoprim Tablets Work?

Trimethoprim is an antibiotic that works by targeting a specific enzyme called dihydrofolate reductase, which is essential for the growth and replication of bacteria. Here’s a step-by-step explanation of how Trimethoprim Tablets work:

  • Folate Metabolism in Bacteria: Bacteria require folate (also known as vitamin B9) for the synthesis of DNA, RNA, and certain amino acids. Folate metabolism is a crucial process in bacterial growth and replication.
  • Dihydrofolate Reductase (DHFR): Dihydrofolate reductase is an enzyme that plays a central role in folate metabolism. It converts dihydrofolate (DHF), an inactive form of folate, into tetrahydrofolate (THF), an active form of folate that is necessary for DNA synthesis.
  • Inhibition by Trimethoprim: Trimethoprim works by selectively inhibiting the bacterial enzyme dihydrofolate reductase. It does this by binding to the enzyme and preventing it from converting DHF to THF.
  • Reduced Folate Availability: When dihydrofolate reductase is inhibited by Trimethoprim, bacteria are unable to produce sufficient THF. As a result, they cannot synthesize the essential building blocks needed for DNA and RNA replication, as well as for the production of certain amino acids.
  • Bacterial Growth Inhibition: The inhibition of folate metabolism disrupts the bacterial cell’s ability to replicate and grow. This ultimately leads to the suppression of bacterial growth and division.
  • Immune System Eradication: While Trimethoprim inhibits bacterial growth, it also allows the body’s immune system to recognize and eliminate the existing bacteria more effectively. This is because bacterial growth is slowed down, making it easier for the immune system to target and destroy the bacteria.

By specifically targeting dihydrofolate reductase and disrupting folate metabolism in bacteria, Trimethoprim effectively stops the growth and multiplication of susceptible bacteria. This makes it an effective antibiotic for treating bacterial infections. Trimethoprim primarily affects bacterial cells and has limited impact on human cells because human cells obtain folate through dietary sources rather than synthesizing it as bacteria do. However, as with any antibiotic, Trimethoprim should be used only as prescribed by a healthcare professional to ensure effective treatment and minimize the risk of antibiotic resistance.

Benefits and Side Effects of Trimethoprim Tablets?

Trimethoprim tablets are an antibiotic medication used to treat bacterial infections. Like all medications, they come with both benefits and potential side effects. Here’s an overview of the benefits and common side effects associated with Trimethoprim Tablets:

Benefits:

  • Effective Bacterial Infection Treatment: Trimethoprim is effective against a wide range of bacterial infections, including urinary tract infections (UTIs), respiratory infections, and skin and soft tissue infections. It is often prescribed when the causative bacteria are susceptible to this antibiotic.
  • Rapid Symptom Relief: Trimethoprim can provide rapid relief from the symptoms of bacterial infections. For example, it can alleviate the pain, burning sensation, and frequent urination associated with UTIs.
  • Prevention of Complications: Prompt treatment with Trimethoprim can help prevent the progression of bacterial infections to more severe stages or complications, such as kidney infections in the case of UTIs.
  • Well-Tolerated: In many cases, Trimethoprim is well-tolerated by patients, and side effects are relatively rare.

Side Effects:

  • Gastrointestinal Disturbances: Some people may experience gastrointestinal side effects, such as nausea, vomiting, diarrhea, or abdominal pain while taking Trimethoprim.
  • Allergic Reactions: Allergic reactions to Trimethoprim are rare but can include symptoms like rash, itching, swelling, severe dizziness, and difficulty breathing. If you experience any signs of an allergic reaction, seek medical attention immediately.
  • Skin Sensitivity: Increased sensitivity to sunlight (photosensitivity) is a possible side effect. It’s advisable to use sunscreen and protective clothing when exposed to sunlight during Trimethoprim treatment.
  • Blood Disorders: In rare cases, Trimethoprim may affect blood cell production, leading to conditions such as anemia, leukopenia (reduced white blood cells), or thrombocytopenia (reduced platelets). Regular blood tests may be necessary to monitor blood cell counts during treatment.
  • Liver and Kidney Function: Trimethoprim can occasionally affect liver and kidney function. Your healthcare provider may monitor your liver and kidney function while you are on the medication.
  • Mouth and Tongue Inflammation: Some individuals may experience inflammation or sores in the mouth or on the tongue.
  • Digestive Candidiasis: Trimethoprim treatment can sometimes lead to an overgrowth of the yeast Candida in the digestive tract, resulting in oral or genital thrush (yeast infection).

It’s essential to take Trimethoprim exactly as prescribed by your healthcare provider and to complete the full course of treatment, even if you start feeling better before finishing the medication. This helps ensure that the infection is fully treated and reduces the risk of antibiotic resistance.

If you experience any concerning or severe side effects while taking Trimethoprim, contact your healthcare provider promptly. They can assess your condition and make any necessary adjustments to your treatment plan.

Frequently asked questions (FAQs) about Trimethoprim Tablets:

  1. What is Trimethoprim, and what is it used for?

Trimethoprim is an antibiotic medication used to treat various bacterial infections, including urinary tract infections (UTIs), respiratory infections, and skin infections.

  1. How does Trimethoprim work?

Trimethoprim works by inhibiting a bacterial enzyme called dihydrofolate reductase, which is essential for bacterial DNA synthesis. This action prevents bacterial growth and replication.

  1. What are the common side effects of Trimethoprim Tablets?

Common side effects may include gastrointestinal symptoms (nausea, vomiting, diarrhea), skin sensitivity to sunlight, and, rarely, blood cellrelated issues. Allergic reactions are possible but rare.

  1. How should I take Trimethoprim Tablets?

Follow your healthcare provider’s instructions precisely. Typically, Trimethoprim is taken by mouth with or without food. It’s essential to complete the full prescribed course of treatment, even if symptoms improve.

  1. Can I drink alcohol while taking Trimethoprim?

It’s generally advisable to avoid alcohol while taking antibiotics, including Trimethoprim, to prevent potential interactions and to ensure the medication’s effectiveness.

  1. Are there any drug interactions with Trimethoprim?

Trimethoprim can interact with certain medications, including blood thinners, diuretics, and medications that affect kidney function. Inform your healthcare provider about all the medications you are taking.

  1. Can I take Trimethoprim if I’m pregnant or breastfeeding?

Discuss the use of Trimethoprim with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will weigh the potential benefits and risks.

  1. How quickly should I expect to see improvements in my symptoms when taking Trimethoprim for an infection?

Improvement in symptoms can vary depending on the type and severity of the infection. Some people may experience relief within a day or two, while others may take longer. Always complete the full course of treatment as prescribed.

  1. Can I share my Trimethoprim prescription with someone else with similar symptoms?

No, you should never share prescription medications with others. Each person’s condition may be different, and sharing medications can be unsafe and ineffective.

  1. What should I do if I miss a dose of Trimethoprim?

If you miss a dose, take it as soon as you remember. If it’s close to the next scheduled dose, skip the missed one and continue with the regular dosing schedule. Do not double dose to make up for a missed dose.

As Trimethoprim Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Trimethoprim Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Trimethoprim Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Trimethoprim Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Trimethoprim Tablets 100mg
B. Trimethoprim Tablets 200mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Trimethoprim Tablets 100mg
Each Un-coated tablet contains:
Trimethoprim BP ………………100mg
Excipients……………………………. q.s.


B) Trimethoprim Tablets 200mg
Each Un-coated tablet contains:
Trimethoprim BP ………………200mg
Excipients……………………………. q.s.

THERAPEUTIC INDICATIONS:

Trimethoprim Tablets belong to a group of medicines known as antibacterials. They are used to kill a wide range of bacteria that cause infections in your body, primarily urinary and respiratory tract infections. This medicine can also be used for prevention of recurrent urinary tract infections.
It is particularly useful in women with a simple UTI and short 3 days course usually eradicates the infection completely.

CAUTION & WARNING:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH
A BROAD-SPECTRUM ANTIBIOTIC THAT IS PARTICULARLY EFFECTIVE FOR USE IN CYSTITIS AND URINARY TRACK INFECTIONS (UTIS)
Increasing your water intake also helps to flush the bacteria out.
****Oral Tablet.
Read enclosed leaflet before use.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
Prescription-only medication for treat cystitis/UTI
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F).
Do not store in the bathroom.
Dosage:
Recommended dose for cystitis: -
One tablet to be taken twice a day (every 12 hours) for 3 days with a full glass of water.
Usual adult dose for Urinary Track Infection:
100mg orally every 12 hours or 200mg orally every 24 hours.
Attach dispensing label as per end country.