Recombinant Streptokinase for Injection BP 1,00,000 IU (0.1MIU)

Recombinant Streptokinase for Injection BP 1,00,000 IU (0.1MIU) Technical Specification:

GENERIC NAME OF MEDICINAL PRODUCT:

• Recombinant Streptokinase for Injection BP (1,00,000 IU)

 QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Recombinant Streptokinase for Injection BP (1,00,000 IU)
  a) Each lyophilized vial (Upon adding 2ml of WFI) contains:
  Streptokinase B.P………………………1,00,000 IU
  Excipients: Glycine, Sodium L Glutamate, Phosphate Buffer

THERAPEUTIC INDICATIONS:

• Acute Evolving Myocardial Infarction
• Acute Massive Pulmonary Embolism
• Deep Vein Thrombosis
• Arterial Thrombosis or Embolism
• Arteriovenous Cannulae Occlusion.

DIRECTION OF USE:

For Intravenous use only.
The solution should be used within 24 hours following reconstitution.
Roll and tilt the vial gently to reconstitute. Avoid shaking as it may cause foaming.
Do not add other medication to the container of the Product.
The unused reconstituted drug should be discarded.
Reconstitute with Sterile Sodium Chloride Injection USP.
For more information refer pack insert.

CAUTION & WARNING:

CAUTION: The injection should not be used if it contains visible solid particles after reconstitution.
Please do not use the solution and return the vial for free replacement.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
WARNING:  Not to be sold by retail without the prescription of a Registered Medical Practitioner only.
Kindly do not self-administer

STORAGE & DOSAGE:

Storage: Store at a temperature between 2°C to 8°C. Protect from light and moisture.
Do not freeze.
Keep all medicines out of reach of children.
Purified Lyophilized vial sealed in a vacuum.
Discard any unused portion.
Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals stands out as a trusted provider of Recombinant Streptokinase for Injection BP, offering compelling reasons for its preferred status in the pharmaceutical industry. With a proven track record spanning years, Taj Pharmaceuticals has earned a reputation for excellence in producing pharmaceuticals of the highest quality, ensuring stringent adherence to quality standards. Quality assurance is paramount at Taj Pharmaceuticals, with a steadfast commitment to maintaining the highest standards throughout the manufacturing process. This commitment ensures that Recombinant Streptokinase for Injection BP is meticulously crafted, a crucial factor when dealing with medications used in critical medical situations.

Recombinant Streptokinase is employed in thrombolytic therapy to dissolve blood clots, making safety and efficacy paramount. Taj Pharmaceuticals places a strong emphasis on these aspects, subjecting their products to rigorous testing to not only meet but often exceed regulatory requirements. This dedication guarantees the safety and effectiveness of the medication for patients in need. Taj Pharmaceuticals specializes in thrombolytic agents, particularly Recombinant Streptokinase. Their team comprises experienced professionals who possess a deep understanding of the complexities and specific demands associated with thrombolytic therapy. This expertise ensures the consistent production of dependable and effective medication.

With a global presence, Taj Pharmaceuticals ensures that healthcare providers and patients around the world have access to Recombinant Streptokinase for Injection BP. This extensive reach underscores their commitment to meeting the diverse needs of medical professionals and patients, regardless of geographical location. Customer satisfaction is at the core of Taj Pharmaceuticals’ philosophy. Their dedication to delivering top-quality products is complemented by outstanding customer service. This customer-centric approach ensures that healthcare providers and patients have a positive and reliable experience when selecting Recombinant Streptokinase for Injection BP from Taj Pharmaceuticals. Taj Pharmaceuticals is a trusted and reliable choice for Recombinant Streptokinase for Injection BP. Their long-standing experience, unwavering commitment to quality, specialized expertise in thrombolytic therapy, global reach, and dedication to customer satisfaction make them the preferred supplier for healthcare providers and patients seeking this crucial medication for thrombolytic therapy.

What is Recombinant Streptokinase for Injection and its uses?

Recombinant Streptokinase for Injection is a medication used in the field of medicine as a thrombolytic agent. It plays a crucial role in dissolving blood clots, a process known as thrombolysis. Here’s an overview of Recombinant Streptokinase and its primary uses:

• Thrombolytic Medication: Recombinant Streptokinase is a thrombolytic medication used to break down and dissolve blood clots. It achieves this by activating a substance called plasminogen in the blood, which then converts into plasmin, an enzyme responsible for breaking down fibrin, a protein involved in blood clot formation.
• Treatment of Acute Myocardial Infarction (Heart Attack): One of the most critical applications of Recombinant Streptokinase is in the management of acute myocardial infarction, commonly known as a heart attack. When administered promptly after the onset of a heart attack, it can help dissolve the blood clot blocking the coronary artery, restoring blood flow to the heart muscle. This rapid intervention can reduce the extent of heart muscle damage and improve the chances of survival.
• Pulmonary Embolism: Recombinant Streptokinase is also used in the treatment of acute pulmonary embolism. In this condition, blood clots obstruct the pulmonary arteries, which carry blood to the lungs. By breaking down these clots, the medication helps improve blood flow to the lungs and relieve potentially life-threatening symptoms.
• Deep Vein Thrombosis (DVT): DVT is a condition where blood clots form in the deep veins, typically in the legs. Recombinant Streptokinase may be used to dissolve these clots, reducing the risk of complications such as pulmonary embolism.
• Arterial Thrombosis: In some cases, Recombinant Streptokinase can be employed to treat arterial thrombosis, where blood clots form in arteries. This may include conditions like acute limb ischemia, where blood flow to a limb is compromised due to a clot.

It’s important to note that Recombinant Streptokinase should be administered under the supervision of a healthcare professional, and the dosage and duration of treatment will depend on the specific medical condition being treated. The use of thrombolytic therapy carries risks, including bleeding, and its benefits must outweigh these potential risks. Additionally, not all patients are suitable candidates for thrombolytic therapy, and decisions regarding its use are based on careful evaluation of the individual’s medical history and the circumstances surrounding the condition. The timely administration of Recombinant Streptokinase can be life-saving in certain situations, particularly in the context of heart attacks and pulmonary embolisms, but it requires careful clinical assessment and management.

How Does Recombinant Streptokinase for Injection Work?

Recombinant Streptokinase for Injection works by utilizing a biochemical process called thrombolysis to break down blood clots within the bloodstream. Here’s how it works:

• Activation of Plasminogen: When Recombinant Streptokinase is injected into the bloodstream, it does not directly attack the blood clot. Instead, it initiates a cascade of biochemical reactions. One of its primary actions is to bind to a substance called plasminogen, which is naturally present in the blood.
• Conversion to Plasmin: Once bound to plasminogen, Recombinant Streptokinase triggers the conversion of plasminogen into its active form, plasmin. Plasmin is an enzyme that plays a crucial role in breaking down fibrin, a protein that forms the structural framework of blood clots.
• Fibrinolysis: Plasmin, once activated, begins to break down the fibrin strands within the blood clot. Fibrinolysis is the process of enzymatically dissolving the fibrin meshwork that holds the blood clot together. As plasmin works on the clot, it gradually breaks it down into smaller fragments.
• Clot Dissolution: Over time, as plasmin continues to degrade fibrin, the blood clot becomes progressively smaller and less stable. Eventually, the clot is completely dissolved into soluble products. This process restores blood flow in the affected blood vessel, alleviating the blockage.
• Restoration of Blood Flow: By dissolving the blood clot, Recombinant Streptokinase helps to restore normal blood flow in the affected blood vessel. This can be lifesaving in conditions like acute myocardial infarction (heart attack) or pulmonary embolism, where prompt restoration of blood flow is essential to prevent tissue damage or organ failure.

It’s important to note that Recombinant Streptokinase does not distinguish between harmful clots and beneficial clots (such as those involved in wound healing). Therefore, its use must be carefully considered by healthcare professionals and administered only in situations where the benefits of clot dissolution outweigh the potential risks, which can include bleeding. Additionally, Recombinant Streptokinase is not the only thrombolytic agent available; there are others with different properties and mechanisms of action. The choice of thrombolytic therapy is based on the specific clinical condition, the patient’s medical history, and other factors, and should be determined by a healthcare provider.