Paracetamol Intravenous Infusion BP 0.5% w/v (Parataj I.V.) Technical Specification:

Product Name:Paracetamol Intravenous Infusion BP 0.5% w/v or 500mg/100ml
Brand Name:Parataj I.V.
Strength:(1% w/v or 1000mg/100ml), (0.5% w/v or 500mg/100ml)
Dosage Form:I.V. Infusion Bottle (LVP)
Packing:100mL IV Bottle
Route of Administration:For I.V. use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Analgesic & Anti-pyretic
Indication: Short-term treatment of moderate pain, especially following surgery, and for the short-term treatment of fever
Storage:Store below 25°C. Protect from Light. Do not freeze.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Paracetamol Intravenous Infusion BP 0.5% w/v or 500mg/100ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Paracetamol Intravenous Infusion BP 0.5% W/V or 500mg/100ml
    Composition:
    Each 100 ml contains:
    Paracetamol BP……….500 mg
    Water for Injection BP………q.s.

THERAPEUTIC INDICATIONS:

Paracetamol I.V. are Short-term treatment of moderate pain, especially following surgery, and for the short-term treatment of fever.

DIRECTION OF USE:

To be used with Non-pyrogenic IV. administration set with aseptic technique.

For I.V Use only.

CAUTION & Warning:

CAUTION: Even Invisible damage to bottle during transit, Storage or handling may result in contamination. Do not use if contamination is found leaking on squeezing, content not clear or contains visible solid particle.

WARNING: Overdose of Paracetamol may be injurious to liver. Not to be given with any other paracetamol containing products. Discard any unused solution immediately after initial use.

WARNING: To be sold by the retailers on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store below 25°C.
Protect from Light.
Do not freeze.

Keep all medicines out of reach of children.
FOR HUMAN USE ONLY
Read enclosed leaflet before use.

Dosage:  As directed by Physician.

Why Taj Pharmaceuticals?

When it comes to your healthcare needs, Taj Pharma stands out as a trusted name in pharmaceuticals, and our Paracetamol Intravenous Infusion BP is no exception. With a legacy of pharmaceutical excellence, we prioritize your well-being, offering a top-tier solution for pain management. Our Paracetamol Intravenous Infusion BP is meticulously formulated and rigorously tested to meet the highest quality and safety standards. Healthcare professionals worldwide rely on Taj Pharma for our unwavering commitment to patient care and product quality. Our Paracetamol IV infusion is no different, providing swift and effective relief for pain and fever. Rest easy knowing that Taj Pharma’s dedication to your health is backed by years of experience and innovation.

Experience the difference of Taj Pharma’s Paracetamol Intravenous Infusion BP today. Choose safety, reliability, and effectiveness in every dose. Your health is our priority, and we deliver on that promise with every product we offer.

What is Paracetamol Intravenous Infusion BP and its use?

Paracetamol Intravenous Infusion BP (British Pharmacopoeia) is a pharmaceutical product that contains paracetamol (also known as acetaminophen) in a form suitable for intravenous administration. Paracetamol is a widely used over-the-counter medication known for its pain-relieving (analgesic) and fever-reducing (antipyretic) properties. However, the intravenous formulation is typically used in healthcare settings, administered by healthcare professionals, and not available for self-administration.

Here are some key points about Paracetamol Intravenous Infusion BP and its uses:

  • Pain Management: Paracetamol intravenous infusion is often used for the management of moderate to severe pain, especially in situations where oral administration may not be possible or effective.
  • Fever Reduction: It is also employed to reduce fever, particularly in cases where oral paracetamol may not be suitable, such as patients with difficulty swallowing or those who cannot tolerate oral medications.
  • Post-Surgical Pain: Paracetamol IV infusion is commonly used in post-operative care to provide pain relief to patients who have undergone surgery.
  • Hospital Setting: This formulation is typically administered in a hospital or clinical setting, under the supervision of healthcare professionals. It allows for precise dosing and monitoring.
  • Intravenous Administration: The medication is given intravenously, which means it is delivered directly into the bloodstream through a vein. This route of administration allows for rapid onset of action.
  • Safety and Efficacy: Paracetamol Intravenous Infusion BP is formulated to meet strict quality and safety standards. It is considered safe and effective when administered correctly.
  • Dosage: The dosage and frequency of administration will depend on the patient’s age, weight, medical condition, and the healthcare provider’s recommendations.

It’s important to note that while paracetamol is generally considered safe when used as directed, improper use or overdose can lead to serious health issues, including liver damage. Therefore, the intravenous formulation should only be administered by healthcare professionals who are trained to use it safely and effectively. Patients should always follow their healthcare provider’s instructions and seek medical guidance if they have any concerns or questions about its use.

How does Paracetamol Intravenous Infusion BP Work?

Paracetamol Intravenous Infusion BP (British Pharmacopoeia) works in a manner similar to its oral counterpart, but its intravenous administration allows for faster and more predictable absorption into the bloodstream. Paracetamol, also known as acetaminophen, is a medication primarily used for its pain-relieving (analgesic) and fever-reducing (antipyretic) properties. Here’s how it works:

  • Pain Relief: Paracetamol works by inhibiting the production of prostaglandins in the brain. Prostaglandins are substances that promote inflammation, pain, and fever. When an injury or illness occurs, prostaglandin levels increase, causing pain and fever. Paracetamol reduces the production of prostaglandins in the brain, which results in decreased pain perception.
  • Fever Reduction: Paracetamol helps lower fever by acting on the hypothalamus in the brain, which regulates body temperature. By reducing prostaglandin levels in this region, paracetamol allows the body to reset its temperature to a lower, more normal range.
  • Central Mechanism: Unlike non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin, paracetamol primarily exerts its effects in the central nervous system (the brain and spinal cord) and does not have significant anti-inflammatory properties. This makes it suitable for pain and fever relief without the potential for stomach irritation or bleeding associated with NSAIDs.
  • Intravenous Administration: The intravenous (IV) form of paracetamol allows for rapid delivery of the medication directly into the bloodstream. This means that the onset of action is quicker compared to oral forms, making it particularly useful in cases where immediate pain relief or fever reduction is necessary.
  • Precise Dosing: In a healthcare setting, the IV administration of paracetamol allows for precise dosing, ensuring that the patient receives the appropriate amount of the medication for their specific needs.
  • Short Duration: The effects of paracetamol are relatively short-lived, typically lasting for a few hours. This necessitates careful monitoring and administration as needed to maintain pain control and fever reduction.

Benefits and Side effects of Paracetamol Intravenous Infusion BP?

Paracetamol Intravenous Infusion BP (British Pharmacopoeia) offers several benefits when used appropriately under the guidance of healthcare professionals. However, like any medication, it may also have potential side effects. Here are the benefits and common side effects associated with Paracetamol Intravenous Infusion:

Benefits:

  • Effective Pain Relief: Paracetamol IV infusion provides effective pain relief for moderate to severe pain, making it particularly valuable in post-operative settings, trauma cases, and other situations where rapid and potent analgesia is required.
  • Fever Reduction: It is effective in lowering fever, helping to normalize body temperature in patients with high fevers due to infections or other medical conditions.
  • Rapid Onset of Action: When administered intravenously, Paracetamol Infusion has a faster onset of action compared to oral forms of paracetamol, providing quicker relief.
  • Precise Dosing: Healthcare professionals can accurately administer the medication, ensuring that patients receive the appropriate dose for their condition.
  • Reduced Risk of Gastric Irritation: Unlike some other pain relievers, such as non-steroidal anti-inflammatory drugs (NSAIDs), Paracetamol does not typically cause stomach irritation or increase the risk of gastrointestinal bleeding.

Side Effects:

  • Hypersensitivity Reactions: Some patients may experience allergic reactions, including skin rashes, itching, and swelling. Severe allergic reactions are rare but possible.
  • Injection Site Reactions: Pain, redness, or swelling at the injection site may occur. These reactions are usually mild and temporary.
  • Liver Toxicity (Rare): While paracetamol is generally considered safe when used within recommended dosages, excessive or prolonged use can lead to liver damage. This risk is heightened when higher doses are administered, or when there is pre-existing liver disease.
  • Blood Disorders (Rare): In rare cases, paracetamol may affect the production of blood cells, leading to conditions such as thrombocytopenia (low platelet count) or leukopenia (low white blood cell count).
  • Nausea and Vomiting: Some patients may experience mild gastrointestinal symptoms, such as nausea or vomiting, although these side effects are less common with IV administration compared to oral forms.
  • Respiratory Depression (Rare): In very rare cases, especially when high doses are administered rapidly, paracetamol may suppress respiratory function. This is more likely in vulnerable populations, such as patients with respiratory conditions.

It’s essential for healthcare professionals to monitor patients receiving Paracetamol Intravenous Infusion for any adverse reactions and to administer the medication according to recommended dosages and guidelines. Patients should also inform their healthcare provider of any allergies or pre-existing medical conditions before receiving this medication. As with any medication, the benefits of using Paracetamol Intravenous Infusion should be weighed against the potential risks, and it should be used with caution in specific patient populations, such as those with liver disease or a history of allergic reactions.

Frequently asked questions (FAQs) about Paracetamol Intravenous Infusion BP:

  1. What is Paracetamol Intravenous Infusion BP?

Paracetamol Intravenous Infusion BP is a pharmaceutical product containing paracetamol (acetaminophen) in an intravenous formulation. It is used for pain relief and fever reduction in hospital settings.

  1. How is Paracetamol Intravenous Infusion administered?

It is administered intravenously, which means it is delivered directly into the bloodstream through a vein. Healthcare professionals typically handle the administration.

  1. What are the common uses of Paracetamol Intravenous Infusion BP?

It is commonly used for the management of moderate to severe pain and for reducing fever, particularly in postoperative care and situations where oral administration may not be suitable.

  1. Is Paracetamol Intravenous Infusion BP safe?

When used as directed and under medical supervision, Paracetamol Intravenous Infusion is generally considered safe. However, like any medication, it has potential side effects and risks, especially if not administered correctly.

  1. What is the recommended dosage of Paracetamol Intravenous Infusion?

The dosage varies based on the patient’s age, weight, medical condition, and the healthcare provider’s recommendations. It’s crucial to follow the prescribed dosage and administration instructions.

  1. Can Paracetamol Intravenous Infusion be used at home?

Typically, it is administered in a hospital or clinical setting by healthcare professionals. It is not meant for selfadministration at home.

  1. What are the potential side effects of Paracetamol Intravenous Infusion?

Common side effects may include injection site reactions, hypersensitivity reactions, nausea, and vomiting. Severe allergic reactions and liver toxicity are rare but possible.

  1. Can Paracetamol Intravenous Infusion interact with other medications?

It’s essential to inform your healthcare provider about all medications you are taking, including overthecounter drugs and supplements, as interactions are possible.

  1. Is Paracetamol Intravenous Infusion suitable for everyone?

It should be used with caution in patients with liver disease, a history of allergic reactions to paracetamol, or certain medical conditions. It is not recommended for use in infants younger than 2 years without specific medical guidance.

  1. How quickly does Paracetamol Intravenous Infusion work?

When administered intravenously, it typically has a rapid onset of action, providing quicker pain relief and fever reduction compared to oral forms of paracetamol.

  1. What should I do in case of an overdose or adverse reactions to Paracetamol Intravenous Infusion?

Seek immediate medical attention if you suspect an overdose or experience severe side effects. It’s crucial to report any adverse reactions to your healthcare provider.

As Paracetamol Intravenous Infusion BP Exporters; We can cater to export business queries from the following geographies. We are exporting our Paracetamol Intravenous Infusion BP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Paracetamol Intravenous Infusion BP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Paracetamol Intravenous Infusion BP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Paracetamol Intravenous Infusion BP 1% w/v or 1000mg/100ml
B. Paracetamol Intravenous Infusion BP 0.5% w/v or 500mg/100ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Paracetamol Intravenous Infusion BP 1% W/V 1000mg/100ml
Composition:
Each 100 ml contains:
Paracetamol BP……….1000 mg
Water for Injection BP………q.s

B. Paracetamol Intravenous Infusion BP 0.5% W/V or 500mg/100ml
Composition:
Each 100 ml contains:
Paracetamol BP……….500 mg
Water for Injection BP………q.s.


THERAPEUTIC INDICATIONS:

Paracetamol I.V. are Short-term treatment of moderate pain, especially following surgery, and for the short-term treatment of fever.

DIRECTION OF USE:

To be used with Non-pyrogenic IV. administration set with aseptic technique.
For I.V Use only.

CAUTION & WARNING:

CAUTION: Even Invisible damage to bottle during transit, Storage or handling may result in contamination. Do not use if contamination is found leaking on squeezing, content not clear or contains visible solid particle.
WARNING: Overdose of Paracetamol may be injurious to liver. Not to be given with any other paracetamol containing products. Discard any unused solution immediately after initial use.
WARNING: To be sold by the retailers on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store below 25°C.
Protect from Light.
Do not freeze.
Keep all medicines out of reach of children.
FOR HUMAN USE ONLY
Read enclosed leaflet before use.
Dosage: As directed by Physician.