Pantoprazole for Injection 40mg (Pantotaj) Technical Specification:

Product Name:Pantoprazole for Injection
Brand Name:Pantotaj
Strength:40mg
Dosage Form:Lyophilized
Dry Powder Injection (Sterile) *Preservative Free
Packing:1 Vial + 1 Ampule + WFI Tray
Route of Administration:For I.V. use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet)
Documents:COA, MOA, Product Permission, Stability Studies, GMP
Therapeutic use:Proton-pump inhibitor
Indication: Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or “heartburn” caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus.
Storage:Store below 25°C. Protect from light. Do not freeze.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Pantoprazole for Injection (40mg)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Pantoprazole for Injection (40mg)
    Composition:
    Each vial contains:
    Pantoprazole Sodium IP
    (as lyophilized Pantoprazole Sodium)
    Equivalent to Pantoprazole ………40mg
    This pack contains:
    Sodium Chloride Injection IP (0.9%w/v) …………10ml

THERAPEUTIC INDICATIONS:

Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or “heartburn” caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus.

DIRECTION OF USE:

Dissolve the contents in Sodium Chloride Injection IP (0.9%w/v). The reconstituted solution should be used immediately after the preparation.

CAUTION & SCHEDULE:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.

For IV use only after reconstitution.

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE

SCHEDULE: SCHEDULE H PRESCRIPTION DRUG WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store below 25°C. Protect from light. Do not freeze.

Keep all medicines out of reach of children.

Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals is a reputable pharmaceutical company known for its commitment to quality, making it an attractive choice for healthcare providers and patients seeking Pantoprazole for Injection. One of its key strengths lies in its unwavering dedication to maintaining high-quality standards in pharmaceutical manufacturing. This focus on quality assurance ensures that medications, including Pantoprazole for Injection, meet rigorous safety and efficacy standards, instilling confidence in both healthcare providers and patients. With a wealth of experience in the pharmaceutical industry, Taj Pharmaceuticals brings substantial expertise in producing and distributing a wide range of pharmaceutical products. This expertise not only enhances the reliability of their pharmaceutical offerings but also positions them as a trusted and dependable supplier for healthcare professionals and patients alike. Furthermore, Taj Pharmaceuticals places paramount importance on regulatory compliance. The company strictly adheres to regulatory standards and enforces robust quality control procedures. This commitment guarantees that Pantoprazole for Injection complies with essential quality and safety requirements mandated by regulatory authorities, thereby further enhancing patient safety.

Taj Pharmaceuticals’ global presence and well-established distribution network contribute to the accessibility of Pantoprazole for Injection and other pharmaceutical products across diverse regions. This international reach elevates patient care to a global level, ensuring that essential medications are readily available when and where they are needed. Investment in research and development (R&D) is another notable aspect of Taj Pharmaceuticals’ approach. This investment holds the potential to lead to the development of more effective and advanced formulations of Pantoprazole for Injection, potentially improving its therapeutic benefits and patient outcomes. In addition to their commitment to quality, Taj Pharmaceuticals places a strong emphasis on affordability. Competitive pricing options may make Pantoprazole for Injection more accessible to healthcare providers and patients, aligning with the goal of ensuring access to essential medications without imposing financial barriers. Lastly, Taj Pharmaceuticals adopts a patient-centric approach, emphasizing patient well-being and safety. This focus on patient safety aligns seamlessly with the significance of Pantoprazole for Injection in managing gastrointestinal conditions. It reinforces the trust placed in their products by healthcare providers and patients, ultimately contributing to improved patient care and outcomes on a global scale.

What is Pantoprazole for Injection and its uses:

Pantoprazole for Injection is a medication that contains the active ingredient pantoprazole. It is a proton pump inhibitor (PPI), a type of medication that is used to reduce the production of stomach acid. Pantoprazole for Injection is typically administered intravenously (IV) and is used for specific medical purposes. Here are its uses:

  • Gastroesophageal Reflux Disease (GERD): Pantoprazole for Injection is used in the hospital setting to manage severe cases of GERD. GERD is a chronic condition where stomach acid flows back into the esophagus, causing symptoms like heartburn, regurgitation, and chest pain. IV pantoprazole can rapidly reduce stomach acid in patients with severe GERD.
  • Peptic Ulcers: It is used to treat peptic ulcers, which can develop in the stomach (gastric ulcers) or the upper part of the small intestine (duodenal ulcers). Peptic ulcers can cause pain and discomfort, and pantoprazole helps in healing these ulcers by reducing stomach acid production.
  • Zollinger-Ellison Syndrome: Pantoprazole for Injection is effective in managing Zollinger-Ellison Syndrome, a rare condition characterized by the excessive production of stomach acid. In this syndrome, tumors in the pancreas or duodenum lead to overproduction of gastrin, which stimulates the stomach to produce excess acid. Pantoprazole helps control acid levels in patients with this condition.
  • Stress Ulcer Prophylaxis: In critically ill patients admitted to the intensive care unit (ICU) or those at risk of developing stress ulcers due to major surgery or severe illness, Pantoprazole for Injection is administered to prevent the formation of stress ulcers and gastrointestinal bleeding.
  • Upper Gastrointestinal Bleeding: Pantoprazole for Injection is sometimes used in the hospital setting to manage upper gastrointestinal bleeding. By reducing stomach acid production, it can help in the treatment of bleeding ulcers or other bleeding disorders affecting the upper digestive tract.

It’s important to note that Pantoprazole for Injection is typically administered by healthcare professionals in a hospital or clinical setting. The intravenous form allows for rapid and precise control of acid levels in patients with severe gastrointestinal conditions. The dosage and duration of treatment will be determined by a healthcare provider based on the specific medical condition and the patient’s individual needs.

How does Pantoprazole for Injection work?

Pantoprazole for Injection works by inhibiting the activity of proton pumps in the stomach lining. It contains the active ingredient pantoprazole, which is classified as a proton pump inhibitor (PPI). Here’s how Pantoprazole for Injection works to reduce stomach acid production:

  • Proton Pump Inhibition:
    Inside the cells of the stomach lining, there are tiny structures called proton pumps. These proton pumps play a crucial role in the production of gastric acid, which is necessary for digestion but can cause problems when produced excessively. Pantoprazole, as a PPI, works by specifically targeting and inhibiting the activity of these proton pumps.
  • Reduction in Gastric Acid Production:
    When pantoprazole inhibits proton pumps, it effectively blocks the release of acid into the stomach. These pumps are responsible for the final step in the production of stomach acid, which is the secretion of hydrogen ions (protons) into the stomach. As a result, the production of gastric acid is significantly reduced. This reduction leads to a decrease in the acidity of the stomach’s contents.
  • Alleviation of AcidRelated Symptoms:
    By reducing stomach acid production, Pantoprazole for Injection helps alleviate symptoms associated with conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and ZollingerEllison Syndrome. These symptoms may include heartburn, acid regurgitation, chest discomfort, and stomach pain.
  • Promotion of Ulcer Healing:
    For individuals with peptic ulcers, Pantoprazole creates a less acidic environment in the stomach. This allows the ulcer to heal without being constantly irritated by excess acid. The reduction in acid production facilitates the natural healing process.
  • Prevention of AcidInduced Damage:
    In the case of ZollingerEllison Syndrome, where excessive stomach acid production occurs due to tumors, Pantoprazole helps control acid levels and prevents acidinduced damage to the stomach and upper gastrointestinal tract.
  • Stress Ulcer Prophylaxis:
    In ICU patients or those at risk of stress ulcers, Pantoprazole for Injection is used to prevent the formation of ulcers and gastrointestinal bleeding by maintaining a controlled and reduced level of stomach acid.

Benefits of Pantoprazole for Injection:

  • Effective Acid Reduction: The primary benefit of Pantoprazole for Injection is its ability to significantly reduce the production of stomach acid. This reduction in gastric acid levels is effective in treating various acid-related gastrointestinal conditions.
  • Relief from GERD Symptoms: These injections provide rapid relief from symptoms associated with gastroesophageal reflux disease (GERD), such as heartburn, acid regurgitation, chest discomfort, and throat irritation. By quickly reducing stomach acid, they help alleviate these uncomfortable symptoms.
  • Ulcer Healing: Pantoprazole for Injection is beneficial for individuals with peptic ulcers. It promotes the healing of ulcers by creating a less acidic environment in the stomach, allowing the ulcer to repair itself without constant irritation from excess acid.
  • Management of Zollinger-Ellison Syndrome: In cases of Zollinger-Ellison Syndrome, a rare condition characterized by excessive stomach acid production due to tumors, Pantoprazole helps control acid levels, reducing the risk of severe ulceration and related symptoms.
  • Stress Ulcer Prophylaxis: In critically ill patients admitted to the intensive care unit (ICU) or those at risk of developing stress ulcers due to major surgery or severe illness, Pantoprazole for Injection is administered to prevent the formation of stress ulcers and gastrointestinal bleeding.
  • Upper Gastrointestinal Bleeding: These injections are sometimes used in the hospital setting to manage upper gastrointestinal bleeding. By reducing stomach acid production, they can help in the treatment of bleeding ulcers or other bleeding disorders affecting the upper digestive tract.

Common Side Effects of Pantoprazole for Injection:

  • Injection Site Reactions: Pain, redness, or swelling at the injection site can occur.
  • Headache: Some individuals may experience headaches as a side effect, although these are typically mild and temporary.
  • Nausea and Vomiting: Nausea and vomiting may occur in some cases.
  • Diarrhea or Constipation: Changes in bowel habits, such as diarrhea or constipation, may occur, although these side effects are usually not severe.
  • Dizziness: Dizziness or lightheadedness may occur, particularly when changing positions quickly.
  • Fatigue: Fatigue or drowsiness may occur, but these side effects are generally mild.

Frequently Asked Questions About Pantoprazole for Injection:

Certainly, here are some frequently asked questions (FAQs) about Pantoprazole for Injection:

  1. What is Pantoprazole for Injection used for?

Pantoprazole for Injection is used to treat various gastrointestinal conditions, including gastroesophageal reflux disease (GERD), peptic ulcers, ZollingerEllison Syndrome, stress ulcer prophylaxis in critically ill patients, and upper gastrointestinal bleeding.

  1. How does Pantoprazole for Injection work?

Pantoprazole is a proton pump inhibitor (PPI) that reduces stomach acid production by inhibiting proton pumps in the stomach lining. This reduction in acid helps alleviate symptoms and promote healing in acidrelated conditions.

  1. What is the recommended dosage for Pantoprazole for Injection?

The dosage will depend on the specific condition being treated, the severity of symptoms, and individual patient factors. It’s crucial to follow the prescribed dosage and guidance provided by your healthcare provider.

  1. Can Pantoprazole for Injection be used to relieve heartburn quickly?

Yes, Pantoprazole for Injection can provide rapid relief from heartburn and acidrelated symptoms. Its intravenous administration allows for swift action in reducing stomach acid levels.

  1. Are there any dietary restrictions while taking Pantoprazole for Injection?

Your healthcare provider may provide specific dietary recommendations based on your condition. However, it’s generally advisable to avoid consuming large or spicy meals, caffeine, alcohol, and acidic foods and beverages that can exacerbate symptoms of GERD and acidrelated conditions.

  1. Can I take other medications alongside Pantoprazole for Injection?

Inform your healthcare provider about all medications, including over-the-counter drugs, supplements, and herbal products, that you are taking. Some medications may interact with Pantoprazole for Injection, and dosage adjustments or alternative treatments may be necessary.

  1. How long does it take for Pantoprazole for Injection to show improvement in symptoms?

The onset of symptom relief can vary among individuals and depends on the specific condition being treated. It may take several days to weeks for noticeable improvement. Continue taking the medication as prescribed, even if symptoms do not immediately resolve.

  1. What are the common side effects of Pantoprazole for Injection?

Common side effects may include injection site reactions, headaches, nausea, vomiting, changes in bowel habits (diarrhea or constipation), dizziness, and fatigue. These side effects are generally mild and temporary.

  1. Can I discontinue Pantoprazole for Injection on my own, or should I consult my healthcare provider for discontinuation?

It is not advisable to discontinue Pantoprazole for Injection on your own, especially if it has been prescribed for a specific condition. Consult your healthcare provider for guidance on how to taper and discontinue the medication safely to minimize the risk of rebound symptoms or withdrawal effects.

Always consult with your healthcare provider for personalized guidance and answers to specific questions or concerns you may have about Pantoprazole for Injection and its use.

As Pantoprazole for Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Pantoprazole for Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Pantoprazole for Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Pantoprazole for Injection, Taj Pharmaceuticals Limited to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF MEDICINAL PRODUCT:

A) Pantoprazole for Injection (40mg)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Pantoprazole for Injection (40mg)
 Composition:
a) Each vial contains:
Pantoprazole Sodium IP
(as lyophilized Pantoprazole Sodium)
Equivalent to Pantoprazole ………40mg
b) This pack contains:
Sodium Chloride Injection IP (0.9%w/v) …………10ml


THERAPEUTIC INDICATIONS:

Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or "heartburn" caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus.

DIRECTION OF USE:

Dissolve the contents in Sodium Chloride Injection IP (0.9%w/v). The reconstituted solution should be used immediately after the preparation.

CAUTION & SCHEDULE:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.
For IV use only after reconstitution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
SCHEDULE: SCHEDULE H PRESCRIPTION DRUG WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store below 25°C. Protect from light. Do not freeze.
Keep all medicines out of reach of children.
Dosage: As directed by Physician.