Moxifloxacin Hydrochloride Infusion 400mg/100ml Technical Specification:

Product Name:Moxifloxacin Hydrochloride Infusion (0.4%w/v or 400mg/100ml)
Brand Name:Moxitaj
Strength:(0.4%w/v or 400mg/100m or 4mg/ml)
Dosage Form:I.V. Infusion Bottle (LVP)
Packing:100mL, 250mL IV Bottle
Route of Administration:For I.V. use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-bacterial & Quinolone antibiotics
Indication: Moxifloxacin injection is used to treat bacterial infections in many different parts of the body.
Storage:Protect from light, temperature not exceeding 30°C. Do not freeze.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Moxifloxacin Hydrochloride Infusion (0.4%w/v or 400mg/100ml)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Moxifloxacin Hydrochloride Infusion (0.4% W/V or 400mg/100ml)
    Composition:

    Each 100 ml contains:
    Moxifloxacin Hydrochloride USP
    Eq. to Moxifloxacin……………………………400mg
    Mannitol BP……………………………………… 5%w/v
    Water for Injection USP…………………………. q. s.

THERAPEUTIC INDICATIONS:

Moxifloxacin injection is used to treat bacterial infections in many different parts of the body. It is also used to treat and prevent plague (including pneumonic and septicemic plague). Moxifloxacin belongs to the class of medicines known as quinolone antibiotics.

DIRECTION OF USE:

Warm the bottle before use in case of crystallization.

To be used with Non-pyrogenic IV. administration set with aseptic technique.

CAUTION & WARNING:

CAUTION:  Even Invisible damage to bottle during transit, Storage or handling may result in contamination. Do not use if contamination is found leaking on squeezing, contents not clear or contains visible solid particles.
It is dangerous to take this preparation except in accordance with the medical advice.
Do not use the bottle if plastic bag is missing or tampered.
This drug may cause low blood sugar and mental health related side effects.
WARNING: TO BE SOLD BY THE RETAILERS ON THE PRESCRIPTION OF A REGISTERED MEDICAL PRACTITIONER ONLY.

STORAGE & DOSAGE:

Storage:  Protect from light, moisture & temperature not exceeding 30°C.
Do not freeze.
Keep medicine out of reach of children.
FOR HUMAN USE ONLY
ISOTONIC BUFFER SOLUTION
Dosage:  As directed by Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals is a well-established pharmaceutical company that has earned a reputation for its commitment to producing high-quality medications, including Moxifloxacin Hydrochloride Infusion. There are several compelling reasons why Taj Pharma is a preferred choice for healthcare providers and patients seeking reliable and effective pharmaceutical products. First and foremost, Taj Pharmaceuticals places a strong emphasis on quality assurance throughout the manufacturing process. They adhere to stringent quality control standards, ensuring that their products, including Moxifloxacin Hydrochloride Infusion, meet the highest industry benchmarks for safety, efficacy, and purity. This dedication to quality has earned Taj Pharmaceuticals recognition and trust within the pharmaceutical industry. In addition to their commitment to quality, Taj Pharmaceuticals invests significantly in research and development. Their experienced team of researchers and scientists works tirelessly to improve existing medications and develop new pharmaceutical solutions. This commitment to innovation ensures that their Moxifloxacin Hydrochloride Infusion remains effective and safe for patients. Taj Pharmaceuticals operates with a global perspective, distributing their products to various countries worldwide. This expansive global reach ensures that patients and healthcare providers in diverse regions can access high-quality medications, contributing to better healthcare outcomes on a global scale. Affordability is another key focus for Taj Pharmaceuticals. They strive to offer their medications, including Moxifloxacin Hydrochloride Infusion, at competitive prices, making them accessible to a wide range of patients. This affordability aspect aligns with their mission to improve global healthcare by ensuring that essential medications are within reach for all. Environmental responsibility is an integral part of Taj Pharmaceuticals’ corporate ethos. They engage in sustainable and eco-friendly practices to minimize their environmental impact. This commitment to sustainability aligns with broader efforts to protect the environment and promote a greener future. Beyond Moxifloxacin Hydrochloride Infusion, Taj Pharmaceuticals boasts a diverse portfolio of pharmaceutical products that cater to various medical needs. This extensive range allows healthcare providers to choose appropriate solutions for their patients, addressing a wide spectrum of health conditions. Taj Pharmaceuticals is also known for its dedication to customer support. They provide healthcare professionals with information and assistance related to their products, ensuring that physicians have the resources they need to make informed decisions for their patients. Furthermore, Taj Pharmaceuticals adheres rigorously to regulatory guidelines, ensuring that their medications are safe, effective, and compliant with international standards. In summary, Taj Pharmaceuticals is a trusted pharmaceutical company with a strong commitment to quality, innovation, affordability, and environmental responsibility. Their global presence, research capabilities, and unwavering dedication to excellence make them a reliable choice for healthcare providers and patients seeking high-quality pharmaceutical solutions.

What is Moxifloxacin Hydrochloride Infusion and its uses:

Moxifloxacin Hydrochloride Infusion is a medication used for the treatment of various bacterial infections. It belongs to a class of antibiotics known as fluoroquinolones and is known for its broad-spectrum antibacterial activity. Here are some of the key uses of Moxifloxacin Hydrochloride Infusion:

  • Respiratory Tract Infections: Moxifloxacin is commonly prescribed to treat respiratory tract infections, including acute bacterial sinusitis, community-acquired pneumonia, and exacerbations of chronic obstructive pulmonary disease (COPD). It is effective against a wide range of respiratory pathogens.
  • Skin and Soft Tissue Infections: This infusion may be used to treat skin and soft tissue infections caused by susceptible bacteria. It can be effective against cellulitis, abscesses, and other skin-related bacterial infections.
  • Intra-Abdominal Infections: Moxifloxacin is sometimes prescribed for the treatment of intra-abdominal infections, such as peritonitis or abscesses, when caused by susceptible bacteria.
  • Infectious Diarrhea: In some cases, Moxifloxacin may be used to treat infectious diarrhea, particularly when caused by specific bacterial pathogens that are susceptible to the medication.
  • Urinary Tract Infections: It can be used to treat uncomplicated urinary tract infections caused by susceptible bacteria.
  • Sexually Transmitted Infections: Moxifloxacin may be prescribed for the treatment of certain sexually transmitted infections, such as non-gonococcal urethritis or cervicitis, when caused by susceptible bacteria.

It’s essential to note that Moxifloxacin Hydrochloride Infusion should only be used under the guidance and prescription of a qualified healthcare professional. The choice of antibiotic and its use should be based on the specific type of infection, the susceptibility of the bacteria causing the infection, and other patient-specific factors. Additionally, it’s crucial for patients to complete the full course of treatment, even if their symptoms improve before finishing the medication, to ensure the infection is completely eradicated and to prevent antibiotic resistance.

How do Moxifloxacin Hydrochloride Infusion work?

Moxifloxacin Hydrochloride Infusion works by inhibiting the activity of bacterial enzymes called DNA gyrase and topoisomerase IV. These enzymes are essential for the replication, repair, and maintenance of bacterial DNA.

Here’s how Moxifloxacin’s mechanism of action works:

  • DNA Gyrase Inhibition: DNA gyrase is an enzyme that helps in the unwinding and supercoiling of bacterial DNA during replication. Moxifloxacin binds to the DNA gyrase enzyme and prevents it from carrying out its normal function. This interference with DNA gyrase activity disrupts the bacterial DNA replication process, leading to the formation of abnormal DNA structures.
  • Topoisomerase IV Inhibition: Topoisomerase IV is another enzyme crucial for bacterial DNA metabolism. Moxifloxacin also inhibits the activity of topoisomerase IV. By interfering with this enzyme, the drug further disrupts DNA replication and repair in bacteria. As a result of these dual inhibitory actions, Moxifloxacin effectively interferes with the bacterial cell’s ability to replicate and repair its DNA. This leads to the following effects:
  • Inhibition of bacterial growth and reproduction: Bacteria are unable to divide and multiply effectively, slowing down or stopping the spread of infection.
  • Bactericidal action: Moxifloxacin’s interference with DNA processes can ultimately lead to the death of susceptible bacteria, making it a bactericidal (killing) antibiotic.
  • Treatment of infections: By targeting the DNA processes of bacteria, Moxifloxacin helps to eliminate the infection and alleviate the associated symptoms.

It’s important to note that Moxifloxacin is effective against a wide range of bacteria, both Gram-positive and Gram-negative, making it a broad-spectrum antibiotic. However, it should only be used when prescribed by a healthcare professional and for the specific type of infection it is intended to treat. Overuse or misuse of antibiotics can contribute to antibiotic resistance, which is a growing global health concern.

Benefits and Side Effects of Moxifloxacin Hydrochloride Infusion:

Moxifloxacin Hydrochloride Infusion is an antibiotic used to treat various bacterial infections. Like any medication, it comes with both benefits and potential side effects. It’s important to use this medication under the guidance of a healthcare professional, as they can assess the risks and benefits for your specific condition. Here are some of the potential benefits and side effects of Moxifloxacin:

Benefits:

  • Effective Against a Wide Range of Bacteria: Moxifloxacin is a broad-spectrum antibiotic, which means it can target and treat a wide variety of bacterial infections, including those caused by both Gram-positive and Gram-negative bacteria.
  • Quick Onset of Action: Moxifloxacin is rapidly absorbed into the bloodstream, allowing for a relatively quick onset of action. This means that it can start working against the infection soon after administration.
  • Oral and Intravenous Options: Moxifloxacin is available in both oral and intravenous forms, providing flexibility in the way it can be administered, depending on the severity of the infection and the patient’s condition.
  • Effectiveness in Respiratory Infections: It is commonly used to treat respiratory infections such as community-acquired pneumonia and acute exacerbations of chronic bronchitis.

Side Effects:

  • Gastrointestinal Disturbances: Common side effects include nausea, vomiting, diarrhea, and abdominal discomfort. Taking the medication with food or a full glass of water can help reduce these side effects.
  • Central Nervous System (CNS) Effects: Some individuals may experience dizziness, headache, or sleep disturbances while taking Moxifloxacin. If you experience these symptoms, it’s advisable to avoid activities that require mental alertness, such as driving.
  • Tendonitis and Tendon Rupture: Rarely, Moxifloxacin has been associated with the risk of tendonitis (inflammation of tendons) and even tendon rupture. This risk may be higher in older adults and those with a history of tendon disorders.
  • Photosensitivity: Some people may become more sensitive to sunlight while taking Moxifloxacin, leading to sunburn more easily. It’s important to use sunscreen and protective clothing when exposed to sunlight.
  • Allergic Reactions: Although rare, severe allergic reactions to Moxifloxacin can occur. Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
  • Clostridium difficile Infection: Prolonged use of antibiotics like Moxifloxacin can disrupt the balance of bacteria in the digestive tract and increase the risk of Clostridium difficile infection, which can cause severe diarrhea.
  • Cardiac Effects: Moxifloxacin may prolong the QT interval in the heart’s electrical activity, potentially leading to an irregular heartbeat. This risk is higher in individuals with certain pre-existing heart conditions.

It’s crucial to use Moxifloxacin only as prescribed by a healthcare provider, complete the full course of treatment, and report any unusual or severe side effects promptly. This will help ensure the safe and effective use of the medication for treating bacterial infections.

Frequently Asked Questions About Moxifloxacin Hydrochloride Infusion:

Certainly, here are some frequently asked questions about Moxifloxacin Hydrochloride Infusion:

  1. What is Moxifloxacin Hydrochloride Infusion used for?

Moxifloxacin Hydrochloride Infusion is an antibiotic medication used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and intraabdominal infections.

  1. How does Moxifloxacin work?

Moxifloxacin works by inhibiting the activity of bacterial enzymes that are essential for DNA replication, ultimately preventing the growth and spread of bacteria.

  1. Is Moxifloxacin Hydrochloride Infusion effective against all types of bacteria?

Moxifloxacin is effective against a wide range of bacteria, but it may not be suitable for treating infections caused by certain antibiotic resistant bacteria. Your healthcare provider will determine the most appropriate treatment based on the type of infection.

  1. How is Moxifloxacin Hydrochloride Infusion administered?

Moxifloxacin can be administered as an intravenous infusion, typically in a healthcare setting such as a hospital or clinic. The dosage and duration of treatment will be determined by your healthcare provider.

  1. What should I do if I miss a dose of Moxifloxacin?

If you miss a dose of Moxifloxacin, it’s essential to contact your healthcare provider or nurse immediately to schedule the missed dose. Do not try to make up for the missed dose by taking extra medication.

  1. Are there any special precautions or warnings associated with Moxifloxacin Hydrochloride Infusion?

Yes, Moxifloxacin carries warnings about the risk of tendonitis and tendon rupture, especially in older adults and individuals with a history of tendon disorders. It may also prolong the QT interval in the heart’s electrical activity, potentially leading to an irregular heartbeat. Your healthcare provider will assess the risks and benefits before prescribing this medication.

  1. Can Moxifloxacin cause allergic reactions?

While rare, severe allergic reactions to Moxifloxacin can occur. If you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.

  1. Can I consume alcohol while taking Moxifloxacin?

It is generally advisable to avoid alcohol while taking Moxifloxacin, as alcohol may interact with the medication and increase the risk of side effects.

  1. Is it safe to drive or operate heavy machinery while taking Moxifloxacin?

Moxifloxacin may cause dizziness or other central nervous system effects. If you experience these symptoms, it’s recommended to avoid activities that require mental alertness, such as driving.

  1. Can Moxifloxacin be used during pregnancy or while breastfeeding?

Moxifloxacin is generally not recommended during pregnancy or breastfeeding, as it may have potential risks to the developing fetus or infant. Consult with your healthcare provider for guidance if you are pregnant or breastfeeding.

Always follow your healthcare provider’s instructions and ask any specific questions you may have about Moxifloxacin Hydrochloride Infusion to ensure safe and effective use.

As Moxifloxacin Hydrochloride Infusion Exporters; We can cater to export business queries from the following geographies. We are exporting our Moxifloxacin Hydrochloride Infusion product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Moxifloxacin Hydrochloride Infusion Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Moxifloxacin Hydrochloride Infusion, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Moxifloxacin Hydrochloride Infusion (0.4%w/v or 400mg/100ml)
B. Moxifloxacin Hydrochloride Infusion (400mg/250ml)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Moxifloxacin Hydrochloride Infusion (0.4% W/V or 400mg/100ml)
Composition:
Each 100 ml contains:
Moxifloxacin Hydrochloride USP
Eq. to Moxifloxacin……………………………400mg
Mannitol BP……………………………………... 5%w/v
Water for Injection USP…………………………. q. s.


B. Moxifloxacin Hydrochloride Infusion (400mg/250ml)
Composition:
Each 100 ml contains:
Moxifloxacin Hydrochloride USP
Eq. to Moxifloxacin……………………………400mg
Mannitol BP……………………………………... 5%w/v
Water for Injection USP…………………………. q. s.

THERAPEUTIC INDICATIONS:

Moxifloxacin injection is used to treat bacterial infections in many different parts of the body. It is also used to treat and prevent plague (including pneumonic and septicemic plague). Moxifloxacin belongs to the class of medicines known as quinolone antibiotics.

DIRECTION OF USE:

Warm the bottle before use in case of crystallization.
To be used with Non-pyrogenic IV. administration set with aseptic technique.

CAUTION & WARNING:

CAUTION: Even Invisible damage to bottle during transit, Storage or handling may result in contamination. Do not use if contamination is found leaking on squeezing, contents not clear or contains visible solid particles.
It is dangerous to take this preparation except in accordance with the medical advice.
Do not use the bottle if plastic bag is missing or tampered.
This drug may cause low blood sugar and mental health related side effects.
WARNING: TO BE SOLD BY THE RETAILERS ON THE PRESCRIPTION OF A REGISTERED MEDICAL PRACTITIONER ONLY.

STORAGE & DOSAGE:

Storage: Protect from light, moisture & temperature not exceeding 30°C.
Do not freeze.
Keep medicine out of reach of children.
FOR HUMAN USE ONLY
ISOTONIC BUFFER SOLUTION
Dosage: As directed by Physician.