Mephentermine Sulphate Injection IP 30mg/ml Technical Specification:

Product Name: Mephentermine Sulphate Injection IP
Brand Name: MEPHITAJ
Strength: 30mg/ml
Dosage Form: Liquid Injection
Packing: 10ml
Route of Administration: For I.M/I.V use.
Pack Insert/Leaflet: PIL (Patient Information Leaflet)
Documents: COA, MOA, Product Permission, Stability Studies, GMP
Therapeutic use: Adrenergic and Dopaminergic Cardiac Stimulants
Indication: Mephentermine Sulphate is cardiac stimulant drug which indirectly act on β-adrenergic receptor & release norepinephrine which lead to vasoconstriction and finally increase the blood pressure. Used for treatment of low blood pressure in hypotensive states.
Storage: Store below 25°C in dry place. Protect from light.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Mephentermine Sulphate Injection IP 30mg/ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Mephentermine Sulphate Injection IP 30mg/ml
    Composition:
    Each ml contains:
    Mephentermine Sulphate IP
    Equivalent to
    Mephentermine …………………30mg
    Methylparaben IP……………….0.18% w/v
    Propylparaben IP………………..0.2% w/v
    (As preservatives)
    Water for Injection IP……….q.s.

THERAPEUTIC INDICATION:

Mephentermine Sulphate is cardiac stimulant drug which indirectly act on β-adrenergic receptor & release norepinephrine which lead to vasoconstriction and finally increase the blood pressure.

Used for treatment of low blood pressure in hypotensive states.

DIRECTION OF USE:

For I.M/I.V use.
Maximum 10 withdrawals.

CAUTION & SCHEDULE:

CAUTION: If any foreign particle is visible in the vial after reconstitution, please do not use the solution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
Discard unused portion.
Precaution: Used with caution during pregnancy, breast feeding, high blood pressure & heart disease.

SCHEDULE: SCHEDULE ‘H’ PRESCRIPTION DRUG-CAUTION:  Not to be sold by retail without the prescription of a Registered Medical Practitioner only.

STORAGE AND DOSAGE:

STORAGE: Store in a dry place at a temperature below 30°C.
KEEP OUT OF REACH AND SIGHT OF CHILDREN.
DOSAGE:  As directed by physician.

Why Taj Pharmaceuticals?

Unlock the benefits of selecting Taj Pharmaceuticals for Mephentermine Sulphate Injection. With a rich history of pharmaceutical expertise, Taj Pharmaceuticals stands as a reliable and reputable source for this vital medication. Our steadfast dedication to upholding the highest standards of quality assurance guarantees the safety and effectiveness of our products, earning the trust of healthcare professionals globally.

At Taj Pharmaceuticals, we prioritize the health and well-being of patients. Our Mephentermine Sulphate Injection undergoes rigorous testing and quality control measures to ensure consistent and dependable performance. We understand the critical role this medication plays in emergency situations, such as treating severe low blood pressure or shock, and we are committed to providing a dependable supply.

Moreover, Taj Pharmaceuticals is dedicated to affordability and accessibility. We strive to make essential medications like Mephentermine Sulphate Injection accessible to a broader population without compromising on quality. This aligns with our broader mission of improving global healthcare by making essential treatments more affordable and readily available.

Choose Taj Pharmaceuticals for Mephentermine Sulphate Injection and experience the perfect fusion of quality, affordability, and reliability. Join healthcare professionals and institutions worldwide who rely on our products to deliver exceptional results and contribute to better patient care.

What is Mephentermine Sulphate Injection and its uses:

Mephentermine Sulphate Injection is a critical medication primarily used in emergency and critical care medicine. It belongs to the class of sympathomimetic amines and is valued for its ability to mimic the actions of certain neurotransmitters in the sympathetic nervous system.

One of its primary functions is vasoconstriction, which means it can constrict blood vessels. This property makes Mephentermine Sulphate Injection a vital tool in the treatment of severe low blood pressure (hypotension) and shock, both of which can be life-threatening conditions. By constricting blood vessels, it swiftly elevates blood pressure, enhancing organ perfusion and overall circulation.

Mephentermine Sulphate Injection finds extensive use in emergency situations, including surgeries, trauma, or obstetric emergencies, where there is a significant risk of severe hypotension or cardiovascular collapse. In such cases, this medication provides rapid and effective support, stabilizing blood pressure and preventing potential organ damage.

Additionally, Mephentermine Sulphate is utilized to address bradycardia, particularly when other interventions have proven ineffective. It also plays a role in obstetrics by countering hypotension resulting from epidural anesthesia or obstetric complications, ensuring adequate blood flow to both the mother and the fetus during childbirth.

In cases of severe anaphylactic shock, Mephentermine Sulphate may be administered to restore blood pressure and mitigate the life-threatening effects of an allergic reaction. It is essential to emphasize that this medication should only be administered by trained healthcare professionals in clinical settings, with close monitoring of dosage and administration to minimize potential complications. Its use is reserved for situations where its vasoconstrictive effects are pivotal for patient stabilization, adhering to established medical guidelines and protocols.

How does Mephentermine Sulphate Injection Work:

Mephentermine Sulphate Injection operates through a mechanism that mimics the actions of neurotransmitters within the sympathetic nervous system. In emergency and critical care medicine, it plays a pivotal role by activating this system, which is responsible for preparing the body’s response to stress or crisis.

This medication triggers the release of norepinephrine and epinephrine, two vital neurotransmitters, from nerve endings as part of the sympathetic nervous system’s activation. These neurotransmitters then embark on a mission, binding to receptors located on various tissues throughout the body, including blood vessels and the heart.

One of the most critical effects of Mephentermine Sulphate is vasoconstriction— the narrowing of blood vessels. When norepinephrine and epinephrine bind to receptors on blood vessels, they induce this narrowing. As a result, peripheral vascular resistance increases, making it more challenging for blood to traverse through these vessels.

This vasoconstrictive action leads to a substantial elevation in blood pressure, which proves invaluable in emergency scenarios. Mephentermine Sulphate Injection is particularly instrumental when patients experience severe hypotension or shock, conditions where raising blood pressure promptly is vital for survival.

Moreover, by augmenting blood pressure and enhancing organ perfusion, Mephentermine Sulphate Injection contributes to the maintenance of essential organ function. It acts as a safeguard against potential organ damage, especially during critical medical conditions or surgical procedures, where stable blood pressure and adequate circulation are paramount.

Benefits of Mephentermine Sulphate Injection:

Mephentermine Sulphate Injection offers several significant advantages in emergency and critical care medicine. Foremost, it serves as a rapid and effective means to elevate blood pressure in emergency situations, particularly when patients face severe hypotension or shock. This ability to support blood pressure is invaluable for stabilizing patients and preventing potential organ damage, ensuring that vital organs receive adequate blood flow and oxygen.

In addition to its primary role in managing blood pressure, Mephentermine Sulphate also finds utility in addressing bradycardia when other interventions prove ineffective. Furthermore, it is employed in obstetrics to counteract hypotension arising from epidural anesthesia or specific obstetric complications, safeguarding both the well-being of the mother and the fetus during childbirth.

Side Effects of Mephentermine Sulphate Injection:

While Mephentermine Sulphate Injection offers critical benefits, it can also present potential side effects. These include the possibility of inducing hypertension (high blood pressure), which necessitates vigilant monitoring during administration. Some individuals may experience an increase in heart rate (tachycardia), palpitations, restlessness, anxiety, nausea, vomiting, tremors, or headaches as side effects.

It is crucial to underscore that Mephentermine Sulphate Injection should only be administered by trained healthcare professionals within clinical settings. The decision to use this medication should be carefully considered, with its benefits weighed against the potential side effects. In situations where its ability to raise blood pressure and improve organ perfusion is indispensable for patient stabilization, the benefits typically outweigh the risks, making it an invaluable tool in emergency and critical care medicine. Patients should always consult and communicate any concerns or queries regarding this medication with their healthcare providers.

Frequently Asked Questions About Mephentermine Sulphate Injection:

Certainly, here are some frequently asked questions about Mephentermine Sulphate Injection:

  1. What is Mephentermine Sulphate Injection used for?

Mephentermine Sulphate Injection is primarily used to rapidly raise blood pressure in emergency situations, such as severe hypotension or shock. It also finds application in managing bradycardia and addressing hypotension during childbirth.

  1. How does Mephentermine Sulphate Injection work?

It works by stimulating the sympathetic nervous system, leading to the release of neurotransmitters like norepinephrine and epinephrine. This results in vasoconstriction, an increase in blood pressure, and enhanced organ perfusion.

  1. Is Mephentermine Sulphate safe for all patients?

This medication should be administered with caution, especially in patients with certain medical conditions, as it can induce hypertension and tachycardia. Its use should be determined by healthcare professionals based on the patient’s specific situation.

  1. What are the common side effects of Mephentermine Sulphate Injection?

Common side effects may include an elevated heart rate (tachycardia), palpitations, restlessness, anxiety, nausea, vomiting, tremors, and headaches.

  1. How is Mephentermine Sulphate Injection administered?

It is typically administered intravenously by trained healthcare professionals in clinical settings. The dosage and rate of administration depend on the patient’s condition and the specific medical situation.

  1. Can Mephentermine Sulphate be used during pregnancy or breastfeeding?

Its use during pregnancy and breastfeeding should be carefully considered, and it should only be administered if the potential benefits outweigh the risks, under the guidance of healthcare providers.

  1. Are there alternatives to Mephentermine Sulphate for raising blood pressure in emergencies?

Yes, there are other medications and interventions available for managing hypotension in emergency situations. The choice of treatment depends on the patient’s condition and the underlying cause of hypotension.

  1. What precautions should be taken when using Mephentermine Sulphate Injection?

Close monitoring of blood pressure and heart rate is essential during administration. It should only be administered by trained healthcare professionals in situations where its benefits are necessary for patient stabilization.

  1. Is Mephentermine Sulphate a controlled substance?

Mephentermine Sulphate is not typically classified as a controlled substance; however, its use is regulated and controlled by medical professionals due to its potent effects on blood pressure and cardiac function.

  1. Can Mephentermine Sulphate Injection be administered outside of a clinical setting?

No, it should only be administered by qualified healthcare professionals within clinical settings where appropriate monitoring and emergency support are readily available.

As Mephentermine Sulphate Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Mephentermine Sulphate Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Mephentermine Sulphate Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Mephentermine Sulphate Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Mephentermine Sulphate Injection IP 30mg/ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Mephentermine Sulphate Injection IP 30mg/ml
Composition:
Each ml contains:
Mephentermine Sulphate IP
Equivalent to
Mephentermine …………………30mg
Methylparaben IP……………….0.18% w/v
Propylparaben IP………………..0.2% w/v
(As preservatives)
Water for Injection IP……….q.s.

THERAPEUTIC INDICATIONS:

Mephentermine Sulphate Injection is cardiac stimulant drug which indirectly act on β-adrenergic receptor & release norepinephrine which lead to vasoconstriction and finally increase the blood pressure.
Used for treatment of low blood pressure in hypotensive states.

DIRECTION OF USE:

For I.M/I.V use.
Maximum 10 withdrawals.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after reconstitution, please do not use the solution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
Discard unused portion.
Precaution: Used with caution during pregnancy, breast feeding, high blood pressure & heart disease.
SCHEDULE: SCHEDULE ‘H’ PRESCRIPTION DRUG-CAUTION: Not to be sold by retail without the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

STORAGE: Store in a dry place at a temperature below 30°C.
KEEP OUT OF REACH AND SIGHT OF CHILDREN.
DOSAGE: As directed by physician.