Lamotrigine Tablets USP 100mg Technical Specification:

 Product Name:                     Lamotrigine Tablets USP 100mg
Brand Name:Generics
Strength:25mg, 50mg, 100mg, 150mg, 200mg
Dosage Form:Tablets (Un-coated)
Route of Administration:Via oral Route
Packing:30s, 90s, 100s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Epileptic, Anticonvulsant
Indication: Lamotrigine tablet use to treat epilepsy and bipolar disorder – NHS.
Storage:Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature].

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Lamotrigine Tablets USP 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  •  Lamotrigine Tablets USP 100mg
    Each uncoated tablet contains:
    Lamotrigine USP……………….100mg
    Excipients………………………………q.s.

THERAPEUTIC INDICATIONS:

Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug.

CAUTION & WARNING:

CAUTION:  Read enclosed leaflet before use.
Keep medicine out of reach of children.

Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage:  Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature].
Dosage:  As directed by the Physician.

Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

Choose Taj Pharma for Lamotrigine Tablets and embark on a journey towards effective epilepsy management. With a legacy of pharmaceutical excellence, Taj Pharma offers a reliable solution for those seeking seizure control. Our Lamotrigine Tablets, crafted with precision and stringent quality control, ensure consistency and efficacy in your treatment. Moreover, our commitment to affordability means you can access this essential medication without straining your budget. Trust Taj Pharma for a partner dedicated to your well-being, and take confident steps towards a brighter, seizure-free future. Choose quality, choose affordability, choose Taj Pharma for epilepsy management you can rely on.

What is Lamotrigine Tablets and its use?

Lamotrigine Tablets are a medication used in the treatment of epilepsy and certain mood disorders. The active ingredient in these tablets is lamotrigine. Here’s an overview of its use and its mechanism of action:

Use of Lamotrigine Tablets:

  • Epilepsy Management: Lamotrigine is primarily prescribed to individuals with epilepsy as an antiepileptic drug (AED). It helps reduce the frequency and severity of seizures in various types of epilepsy, including partial seizures, tonic-clonic seizures, and absence seizures.
  • Bipolar Disorder: Lamotrigine is also used in the treatment of bipolar disorder. It can help stabilize mood swings in individuals with bipolar disorder by reducing the frequency and intensity of manic or depressive episodes.

Lamotrigine Tablets are available in a form that dissolves in liquid, making them suitable for individuals who have difficulty swallowing tablets. The dosage and treatment plan for lamotrigine should be determined by a healthcare provider based on the specific condition being treated and the individual’s response to the medication. It’s important to follow the prescribed regimen carefully to achieve the best results while minimizing the risk of side effects. Patients should not stop taking lamotrigine abruptly without consulting their healthcare provider, as this can lead to seizures or mood swings, depending on the condition being treated.

How does Lamotrigine Tablets Work?

Lamotrigine Tablets work by affecting neurotransmitters and ion channels in the brain, which helps reduce the frequency and severity of seizures in epilepsy and stabilizes mood in bipolar disorder. Here’s how Lamotrigine works:

  • Sodium Channel Blockade: One of the primary mechanisms of action of Lamotrigine is its ability to block voltage-gated sodium channels in neurons. These channels are responsible for the rapid influx of sodium ions into nerve cells during an action potential (the electrical signal that allows nerve cells to communicate). By inhibiting these sodium channels, Lamotrigine reduces the abnormal and excessive firing of neurons that can trigger seizures.
  • Modulation of Glutamate: Lamotrigine may also modulate the release of the neurotransmitter glutamate. Glutamate is an excitatory neurotransmitter that plays a key role in transmitting signals between nerve cells. Excessive glutamate activity can lead to overexcitation of neurons and contribute to seizures. Lamotrigine’s regulation of glutamate release helps stabilize brain activity.
  • Stabilizing Mood: In the context of bipolar disorder, Lamotrigine’s exact mechanism of action is not fully understood, but it is believed to involve the modulation of various neurotransmitters, including glutamate and serotonin. By influencing these neurotransmitters, Lamotrigine can help stabilize mood, reduce the frequency of mood swings, and prevent or mitigate both depressive and manic episodes in individuals with bipolar disorder.

Lamotrigine’s effectiveness may vary from person to person, and the specific mechanism through which it works in the brain is still the subject of ongoing research. The dosage and treatment plan for Lamotrigine should be determined by a healthcare provider based on the individual’s medical condition and response to the medication. Patients taking Lamotrigine should follow their prescribed regimen carefully and consult their healthcare provider if they have any questions or concerns about its use. Abruptly discontinuing Lamotrigine can lead to adverse effects, so it should only be stopped under the guidance of a healthcare professional.

Benefits of Lamotrigine Tablets:

  • Epilepsy Management: Lamotrigine is effective in reducing the frequency and severity of seizures in various types of epilepsy, including partial seizures, tonic-clonic seizures, and absence seizures.
  • Bipolar Disorder Treatment: It is used to stabilize mood and reduce the frequency of mood swings in individuals with bipolar disorder, helping to prevent or alleviate depressive and manic episodes.
  • Well-Tolerated: Lamotrigine is generally well-tolerated and suitable for long-term use, making it a valuable option for chronic conditions like epilepsy and bipolar disorder.
  • Dissolvable Form: Lamotrigine Tablets are available in a form that can be dissolved in liquid, which can be particularly helpful for individuals who have difficulty swallowing tablets.

Common Side Effects of Lamotrigine Tablets:

  • Nausea: Nausea is a common side effect, especially when starting Lamotrigine. Taking it with food can help reduce this side effect.
  • Skin Rash: Skin rashes, including a severe condition called Stevens-Johnson syndrome, are potential side effects. If a rash develops, especially with other symptoms like fever or blistering, seek immediate medical attention.
  • Headache: Some individuals may experience headaches as a side effect, although this often improves over time.
  • Dizziness or Drowsiness: Lamotrigine can cause dizziness or drowsiness in some people, especially when starting the medication or with dose increases.
  • Insomnia or Sleep Disturbances: Sleep-related side effects, including insomnia or unusual dreams, can occur.
  • Upset Stomach: Upset stomach or abdominal discomfort may be experienced by some individuals.
  • Blurred Vision: Blurred vision or other visual disturbances can occur, although these side effects are relatively rare.
  • Mood Changes: In some cases, Lamotrigine may cause mood changes, including mood swings or irritability.

It’s important to note that not everyone will experience these side effects, and their severity can vary from person to person. Patients should report any unusual or severe side effects to their healthcare provider. Lamotrigine should be taken as prescribed and under the supervision of a healthcare professional to maximize its benefits while minimizing the risk of side effects. Abruptly discontinuing Lamotrigine can be dangerous, so any changes to the medication regimen should be discussed with a healthcare provider.

Frequently asked questions (FAQs) about Lamotrigine  Tablets:

  1. What is Lamotrigine, and what conditions is it used to treat?

Lamotrigine is a medication used to treat epilepsy and bipolar disorder. It helps reduce seizures in epilepsy and stabilize mood in bipolar disorder.

  1. How does Lamotrigine work to control seizures and stabilize mood?

Lamotrigine primarily works by blocking sodium channels in nerve cells, reducing the excessive electrical activity that can trigger seizures. Its mechanism in bipolar disorder is not fully understood but involves modulating neurotransmitters like glutamate and serotonin.

  1. Are there any special considerations when taking Lamotrigine Tablets?

Yes, Lamotrigine Tablets should be dissolved in a small amount of liquid before taking. It’s essential to follow the specific instructions provided with the medication.

  1. Is Lamotrigine safe to take during pregnancy or breastfeeding?

It’s crucial to consult with a healthcare provider when pregnant or planning to become pregnant, as the risks and benefits of Lamotrigine during pregnancy may vary. Lamotrigine is also present in breast milk, so it’s important to discuss the potential risks and alternatives when breastfeeding.

  1. Can Lamotrigine cause skin rashes?

Yes, skin rashes are a potential side effect of Lamotrigine, and some rashes can be severe. Any rash, especially with other symptoms like fever or blistering, should be reported to a healthcare provider immediately.

  1. How long does it take for Lamotrigine to start working for seizures or mood stabilization?

The effectiveness of Lamotrigine may vary among individuals. It often takes several weeks or even months to achieve optimal results, and dosages may need to be adjusted.

  1. Can Lamotrigine interact with other medications?

Lamotrigine can interact with some medications, so it’s important to inform your healthcare provider about all the medications you are taking, including overthecounter drugs and supplements.

  1. Can Lamotrigine cause weight gain?

Lamotrigine is generally considered weightneutral, meaning it is less likely to cause significant weight gain compared to some other medications used for mood stabilization.

  1. What should I do if I miss a dose of Lamotrigine?

If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

  1. Can Lamotrigine be used in children and adolescents?

Lamotrigine may be prescribed for children and adolescents under the supervision of a healthcare provider, as it can be used to treat certain forms of epilepsy in this age group.

As Lamotrigine Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Lamotrigine Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Lamotrigine Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Lamotrigine Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

Lamotrigine Tablets USP 25mg
Lamotrigine Tablets USP 50mg
Lamotrigine Tablets USP 100mg
Lamotrigine Tablets USP 150mg
Lamotrigine Tablets USP 200mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

a) Lamotrigine Tablets USP 25mg
Each uncoated tablet contains:
Lamotrigine USP……………….25mg
Excipients……………………………...q.s.

b) Lamotrigine Tablets USP 50mg
Each uncoated tablet contains:
Lamotrigine USP……………….50mg
Excipients……………………………...q.s.

c) Lamotrigine Tablets USP 100mg
Each uncoated tablet contains:
Lamotrigine USP……………….100mg
Excipients………………………………q.s.


d) Lamotrigine Tablets USP 150mg
Each uncoated tablet contains:
Lamotrigine USP……………….150mg
Excipients……………………………...q.s.

e) Lamotrigine Tablets USP 200mg
Each uncoated tablet contains:
Lamotrigine USP……………….200mg
Excipients……………………………...q.s.

THERAPEUTIC INDICATIONS:

Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug.

CAUTION & WARNING:

CAUTION:
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature].
Dosage: As directed by the Physician.
Attach dispensing label as per end country.