Ivermectin Dispersible Tablet USP 12mg Technical Specification:

Product Name:Ivermectin Dispersible Tablet USP
Brand Name:Iverotaj
Strength:3mg, 6mg, 12mg
Dosage Form:Dispersible Tablet (Un-coated)
Route of Administration:Via Oral Route
Packing:10s, 100s
Pack Insert/Leaflet:PIL (Patient Information Leaflet)
Documents:COA, MOA, Stability Studies, GMP
Therapeutic use:Anti-parasitic, Anti-helminthics
Indication: Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections.
Storage:Store at 25°C. Store in cool, dry & dark place Protect from Light & moisture.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Ivermectin Dispersible Tablet USP 12mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  •  Ivermectin Dispersible Tablets USP 12mg
    Each uncoated, Dispersible tablet contains:
    Ivermectin IP …….….…………………..12mg
    Excipients…………………………………..q.s.

THERAPEUTIC INDICATIONS:

Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections.

CAUTION & SHEDULE:

CAUTION:  SWALLOW WHOLE DO NOT CHEW OR CRUSH
Take this medicine on an empty stomach
Tablets should be dispersed in water just before oral administration.

SCHEDULE: SCHEDULE ‘H’ PRESCRIPTION: WARNING: NOT TO BE SOLD BY RETAIL WITHOUT THE registered medical Practitioner.

STORAGE & DOSAGE:

Storage: Store at 25°C. Store in cool, dry & dark place Protect from Light & moisture.
Read enclosed leaflet before use.
Keep medicine out of reach of children.

Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals is a trusted name in the pharmaceutical industry, renowned for its unwavering commitment to quality and patient-centric healthcare solutions. One compelling reason to choose Taj Pharmaceuticals is their steadfast dedication to producing high-quality Ivermectin Dispersible Tablets. These tablets are manufactured in state-of-the-art facilities adhering to stringent global quality standards, ensuring each tablet is pure, effective, and safe. With decades of experience, Taj Pharmaceuticals brings a wealth of expertise to the table. Their track record of excellence and reliability has earned them recognition and trust worldwide. They continuously invest in research and development to improve their products, aligning them with the evolving needs of both patients and healthcare professionals. Accessibility and affordability are core principles at Taj Pharmaceuticals. They believe that essential medications should be accessible to all, and their competitive pricing reflects this commitment. Furthermore, Taj Pharmaceuticals boasts a robust global distribution network, guaranteeing timely access to Ivermectin Dispersible Tablets, regardless of geographic location. Safety is paramount in their operations. Taj Pharmaceuticals adheres rigorously to quality control processes and regulatory standards, ensuring that every tablet leaving their facilities is not only effective but also safe for consumption. In choosing Taj Pharmaceuticals for your healthcare needs, you opt for a partner dedicated to your health, well-being, and peace of mind. Their legacy of quality, accessibility, and affordability sets them apart in the pharmaceutical industry, making them a trusted choice for individuals and healthcare providers alike. Experience healthcare you can rely on by discovering the Taj Pharmaceuticals difference today.

What is Ivermectin Dispersible Tablet and its uses:

Ivermectin Dispersible Tablet is a medication that contains the active ingredient ivermectin. It is an oral tablet formulation of ivermectin and is used for various medical purposes. Here’s more information about Ivermectin Dispersible Tablets and their uses:

  • Treatment of Parasitic Infections: Ivermectin is primarily used to treat a variety of parasitic infections caused by nematode (roundworm) and arthropod (insect) parasites. Some common parasitic infections it can address include:
    Onchocerciasis (River Blindness): Ivermectin is a key medication in the treatment and control of onchocerciasis, a parasitic disease caused by the nematode Onchocerca volvulus. It helps prevent blindness and other complications associated with this condition.
    Lymphatic Filariasis (Elephantiasis): Ivermectin is used in combination with other medications to eliminate the larvae of the nematode parasites responsible for lymphatic filariasis.
    Scabies: Ivermectin may be used to treat scabies, a contagious skin condition caused by the Sarcoptes scabiei mite.
    Strongyloidiasis: It is effective against strongyloidiasis, an intestinal infection caused by the nematode Strongyloides stercoralis.
  • OffLabel Uses: Ivermectin has garnered attention for potential offlabel uses, including the treatment of certain viral infections like COVID19. However, its effectiveness and safety for these purposes are still under investigation and subject to ongoing research.

It’s important to note that the use of Ivermectin should always be prescribed and supervised by a healthcare professional. The appropriate dosage and treatment duration depend on the specific condition being treated and the patient’s medical history. Additionally, while Ivermectin is generally safe when used as prescribed for its approved indications, misuse or selfmedication can lead to side effects and may not be effective for conditions it is not intended to treat.
Always follow the guidance of your healthcare provider and adhere to their recommendations when considering the use of Ivermectin Dispersible Tablets for any medical condition.

How Does Ivermectin Dispersible Tablet Work?

Ivermectin Dispersible Tablets work by interfering with the nervous system and muscle function of certain parasites, ultimately leading to their paralysis and death. Ivermectin is the active ingredient in these tablets, and its mechanism of action is well understood for the treatment of parasitic infections. Here’s how Ivermectin works:

  • Targeted Action on Parasites: Ivermectin has a selective effect on parasitic organisms, particularly nematode (roundworm) and arthropod (insect) parasites, while having minimal impact on human cells. This selective action makes it an effective treatment for parasitic infections.
  • GABA Receptor Agonist: Ivermectin functions as an agonist, or activator, of the gamma-aminobutyric acid (GABA) receptors in the nerve and muscle cells of parasites. GABA is an inhibitory neurotransmitter in the nervous system.
  • Disruption of Nervous System Function: When Ivermectin binds to the GABA receptors in parasites, it enhances the inhibitory effects of GABA. This leads to hyperpolarization of the nerve cells and interferes with the normal transmission of nerve impulses. As a result, the parasites experience paralysis and lose their ability to move and function effectively.
  • Muscle Function Impairment: In addition to affecting the nervous system, Ivermectin also disrupts the muscle function of parasites. The continuous influx of chloride ions into the nerve and muscle cells, due to GABA receptor activation, results in sustained muscle contraction, leading to muscle weakness and paralysis.
  • Death of Parasites: Ultimately, the combination of nervous system disruption and muscle dysfunction causes the parasites to become immobilized and unable to perform vital functions, such as feeding and reproduction. Without these functions, the parasites die, and the host’s immune system can clear them from the body.

Ivermectin’s mechanism of action is highly effective against a wide range of parasitic organisms, including nematodes and arthropods. It is particularly valuable in the treatment of diseases like onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis), where these parasites can cause severe and debilitating health issues. It’s important to note that Ivermectin is specific to parasites and does not have the same effect on human cells. This selectivity is a key factor in its safety and effectiveness when used as prescribed by healthcare professionals for the treatment of parasitic infections.

Benefits and Side Effects of Ivermectin Dispersible Tablet:

Ivermectin Dispersible Tablets offer several benefits in the treatment of parasitic infections, but they also come with potential side effects. Here, we’ll discuss the benefits and common side effects of Ivermectin Dispersible Tablets:

Benefits:

  • Effective Against Various Parasitic Infections: Ivermectin is highly effective against a wide range of parasitic infections caused by nematode (roundworm) and arthropod (insect) parasites. This versatility makes it a valuable tool in treating diseases like onchocerciasis (river blindness), lymphatic filariasis (elephantiasis), scabies, and strongyloidiasis.
  • Prevention of Blindness: Ivermectin is instrumental in preventing blindness associated with onchocerciasis. Regular treatment can significantly reduce the burden of this debilitating disease in affected populations.
  • Low Risk of Resistance: Ivermectin has shown a relatively low risk of parasite resistance when compared to some other antiparasitic medications. This makes it an important tool in combating parasitic infections.
  • Oral Formulation: Ivermectin Dispersible Tablets are taken orally, which makes them convenient for administration and can improve patient compliance compared to some other antiparasitic drugs that require injections.
  • Community-Based Programs: Ivermectin is often used in mass drug administration (MDA) programs in endemic areas. This strategy helps reach a large number of individuals at risk of parasitic infections and contributes to public health efforts to control and eliminate these diseases.

Common Side Effects:

  • Gastrointestinal Disturbances: The most common side effects of Ivermectin include nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and temporary.
  • Dizziness and Fatigue: Some individuals may experience dizziness or fatigue after taking Ivermectin, which can affect their ability to perform tasks that require alertness.
  • Skin Reactions: Skin rashes, itching, and hives are less common side effects but can occur in some individuals.
  • Neurological Effects: In rare cases, especially when high doses are used, Ivermectin can cause neurological side effects such as confusion, tremors, and unsteadiness. These side effects are more likely with high doses.
  • Allergic Reactions: While rare, severe allergic reactions to Ivermectin have been reported. Symptoms may include swelling of the face, lips, tongue, or throat, difficulty breathing, and hives.

It’s important to note that Ivermectin should only be used under the guidance of a healthcare professional, and the benefits of treatment should outweigh the potential risks. The appropriate dosage and duration of treatment depend on the specific parasitic infection being treated and the patient’s medical history. If you experience any concerning side effects or adverse reactions while taking Ivermectin, it’s crucial to seek medical attention promptly. Additionally, Ivermectin should not be used for conditions it is not intended to treat, and its use for unapproved indications should be avoided except in clinical trials or under the guidance of a healthcare provider.

Frequently Asked Questions about Ivermectin Dispersible Tablet:

Certainly, here are some frequently asked questions (FAQs) about Ivermectin Dispersible Tablets:

  1. What is Ivermectin Dispersible Tablet used for?

Ivermectin Dispersible Tablets are primarily used to treat various parasitic infections caused by nematode (roundworm) and arthropod (insect) parasites. Common conditions it treats include onchocerciasis (river blindness), lymphatic filariasis (elephantiasis), scabies, and strongyloidiasis.

  1. How does Ivermectin Dispersible Tablet work?

Ivermectin disrupts the nervous system and muscle function of parasites, leading to their paralysis and eventual death. It has a selective action on parasites, making it effective while having minimal impact on human cells.

  1. Is Ivermectin effective against COVID19?

The use of Ivermectin for the prevention or treatment of COVID19 is a subject of ongoing research and debate. As of my knowledge cut-off date in September 2021, its effectiveness for COVID19 had not been definitively established, and its use for this purpose was not universally recommended by health authorities.

  1. What are the common side effects of Ivermectin Dispersible Tablet?

Common side effects include nausea, vomiting, diarrhea, abdominal pain, dizziness, fatigue, and skin rashes. These side effects are usually mild and temporary.

  1. Can Ivermectin Dispersible Tablet be used in children?

Ivermectin can be used in children, but the dosage should be adjusted based on their age and weight. It is essential to follow the dosing instructions provided by a healthcare professional.

  1. Is Ivermectin safe during pregnancy and breastfeeding?

The safety of Ivermectin during pregnancy and breastfeeding is a matter of concern. It should only be used if the potential benefits outweigh the risks, and its use should be under the guidance of a healthcare provider.

  1. Can Ivermectin be used to prevent parasitic infections?

Yes, Ivermectin is sometimes used as a preventive measure in endemic areas to control parasitic infections through mass drug administration (MDA) programs.

  1. Can Ivermectin Dispersible Tablet interact with other medications?

Ivermectin may interact with certain medications, so it’s important to inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.

  1. How is Ivermectin Dispersible Tablet administered?

Ivermectin Dispersible Tablets are taken orally. The dosage and treatment duration depend on the specific parasitic infection being treated and the patient’s age and weight.

  1. Is Ivermectin available over the counter?

In many countries, Ivermectin is available only by prescription and should be used under the guidance of a healthcare professional. The availability of Ivermectin without a prescription may vary by region and local regulations.

Please note that information and guidelines regarding Ivermectin may evolve, so it’s essential to consult with a healthcare provider or refer to updated sources for the most current and accurate information regarding its use.

As Ivermectin Dispersible Tablet Exporters; We can cater to export business queries from the following geographies. We are exporting our Ivermectin Dispersible Tablet product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Ivermectin Dispersible Tablet Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Ivermectin Dispersible Tablet, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Ivermectin Dispersible Tablet USP 3mg
B) Ivermectin Dispersible Tablet USP 6mg
C) Ivermectin Dispersible Tablet USP 12mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Ivermectin Dispersible Tablets USP 3mg
Each uncoated, Dispersible tablet contains:
Ivermectin IP …….………………….…..3mg
Excipients…………………………………..q.s.

B) Ivermectin Dispersible Tablets USP 6mg
Each uncoated, Dispersible tablet contains:
Ivermectin IP ……………………………..6mg
Excipients…………………………………..q.s.

C) Ivermectin Dispersible Tablets USP 12mg
Each uncoated, Dispersible tablet contains:
Ivermectin IP …….….…………………..12mg
Excipients…………………………………..q.s.


THERAPEUTIC INDICATIONS:

Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections.

CAUTION & SCHEDULE:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH
TAKE THIS MEDICINE ON AN EMPTY STOMACH
Tablets should be dispersed in water just before oral administration.
SCHEDULE: SCHEDULE ‘H’ PRESCRIPTION: WARNING: NOT TO BE SOLD BY RETAIL WITHOUT THE REGISTERED MEDICAL PRACTITIONER.

STORAGE & DOSAGE:

Storage: Store at 25°C. Store in cool, dry & dark place Protect from Light & moisture.
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
Dosage: As directed by the Physician.