Imipramine HCl Tablets USP 25mg Technical Specification:

Product Name:                  Imipramine HCl Tablets USP 25mg
Brand Name:Generics
Strength:10mg, 25mg, 50mg
Dosage Form:Tablets (Film-coated)
Route of Administration:Via oral Route
Packing:30s, 90s, 100s, 500s, 1000s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antidepressant, Central nervous system.
Indication: Imipramine tablets and capsules are used to treat depression. it also used to prevent bedwetting in children. Imipramine is in a class of medications called tricyclic antidepressants.
Storage:Store below 25°C in a dry place. Do not freeze. Keep the container tightly closed in order to protect from moisture.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Imipramine HCl Tablets USP 25mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Imipramine HCl Tablets USP 25mg
    Each film coated tablet contains:
    Imipramine Hydrochloride USP……………….25mg
    Excipients……………………………………………. q.s.
    Colour: Carmoisine Lake

THERAPEUTIC INDICATIONS:

This medication is used to treat depression. it is also used with other therapies for the treatment of night time bed-wetting (enuresis) in children. using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.

CAUTION & WARNING:

CAUTION: Read enclosed leaflet before use.
Keep medicine out of reach of children.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage:  Store below 25°C in a dry place. Do not freeze. Keep the container tightly closed in order to protect from moisture.
Dosage:  As directed by the Physician.

Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals stands as a beacon of trust and excellence in the world of pharmaceuticals, offering Imipramine HCl Tablets that embody the pinnacle of quality and reliability. With an unwavering commitment to delivering pharmaceuticals of the highest standards, Taj Pharmaceuticals ensures the safety and efficacy of each tablet, making them a dependable choice for those in need. Backed by a rich legacy in the pharmaceutical industry, Taj Pharmaceuticals’ Imipramine tablets have a proven track record of providing relief and support to individuals seeking effective medications. Furthermore, their extensive expertise spans a wide range of pharmaceutical products, catering to diverse healthcare needs and placing patient well-being at the forefront. Taj Pharmaceuticals’ dedication to regulatory compliance, global reach, and patient-centric care makes them the preferred partner for healthcare providers and patients alike, providing access to quality healthcare on a global scale. Trust Taj Pharmaceuticals for Imipramine HCl Tablets, where quality and commitment to health converge.

What is Imipramine HCl Tablets and its uses?

Imipramine HCl Tablets contain imipramine hydrochloride, a tricyclic antidepressant that plays a pivotal role in managing various medical conditions. As a powerful medication, imipramine works by altering the balance of neurotransmitters in the brain, specifically serotonin and norepinephrine, to improve mood and mental well-being. Its primary application lies in the treatment of major depressive disorder (MDD), where it combats the symptoms of depression, offering respite from feelings of sadness and hopelessness. Imipramine also finds utility in addressing nocturnal enuresis (bedwetting), reducing the frequency of such episodes. Furthermore, it extends its therapeutic reach to the realm of panic disorder, mitigating the recurrence and intensity of panic attacks. Additionally, imipramine may be used off-label to manage chronic pain syndromes, such as neuropathic pain and fibromyalgia, providing relief for individuals grappling with persistent pain. Imipramine HCl Tablets are typically prescribed by healthcare providers following a comprehensive evaluation, with dosage and treatment duration tailored to individual needs, emphasizing the importance of careful adherence to medical guidance during therapy.

How do Imipramine HCl Tablets work?

Imipramine HCl Tablets operate by influencing the intricate balance of neurotransmitters in the brain, specifically serotonin and norepinephrine. Categorized as a tricyclic antidepressant (TCA), imipramine exerts its therapeutic effects through two primary mechanisms. First, it impedes the reuptake of serotonin and norepinephrine in the synapses, prolonging their presence and enhancing communication between nerve cells. This enhanced neurotransmission is believed to regulate mood, alleviate sadness, and ameliorate symptoms of depression. Second, imipramine may play a role in enhancing brain neuroplasticity, contributing to long-term therapeutic benefits, particularly in conditions like depression and chronic pain. It’s worth noting that the precise mechanisms of action may vary among individuals, and the benefits of imipramine often take time to manifest, underscoring the importance of consistent use under the guidance of a healthcare provider for those seeking its mood-enhancing effects.

Benefits of Imipramine HCl Tablets:

Imipramine HCl Tablets offer a range of therapeutic benefits across different medical conditions. Firstly, they are highly effective in the treatment of major depressive disorder (MDD), significantly improving mood and providing relief from the debilitating symptoms of depression. Additionally, Imipramine plays a crucial role in managing nocturnal enuresis, commonly known as bedwetting, particularly in children. By reducing the frequency of bedwetting episodes during sleep, it can help individuals, especially children, achieve dry nights. Furthermore, Imipramine is employed in the management of panic disorder, where it acts to decrease both the frequency and severity of panic attacks, offering individuals a greater sense of control and relief. Lastly, while used off-label, Imipramine can provide chronic pain relief for individuals suffering from conditions like neuropathic pain and fibromyalgia, improving their quality of life.

Side Effects of Imipramine HCl Tablets:

Like many medications, Imipramine HCl Tablets can be associated with certain side effects. Common side effects include dry mouth, constipation, blurred vision, drowsiness, and dizziness, which are often mild and may lessen over time. However, Imipramine can also produce anticholinergic effects, including dry mouth, constipation, and blurred vision, which may be bothersome for some individuals. Sedation is another potential side effect, and caution is advised when engaging in activities requiring alertness or coordination. Additionally, Imipramine may have cardiovascular effects, albeit rarely, necessitating cardiac monitoring, particularly at higher doses. Weight gain and sexual side effects, such as decreased libido and sexual dysfunction, may occur in some individuals. It’s important to note that abrupt discontinuation of Imipramine can lead to withdrawal symptoms, emphasizing the importance of tapering the dosage under medical supervision. While serious side effects are rare, they may include allergic reactions, blood pressure changes, and liver problems, demanding immediate medical attention. Individual responses to Imipramine may vary, and any concerns or side effects should be promptly discussed with a healthcare provider for appropriate management and adjustment of treatment.

Frequently Asked Questions About Imipramine HCl Tablets:

Certainly, here are some frequently asked questions (FAQs) about Imipramine HCl Tablets:

  1. What is Imipramine HCl, and how does it work?

Imipramine HCl is a medication classified as a tricyclic antidepressant (TCA). It works by affecting the balance of neurotransmitters in the brain, such as serotonin and norepinephrine, to improve mood and alleviate symptoms of depression.

  1. What medical conditions are treated with Imipramine HCl Tablets?

Imipramine HCl Tablets are primarily used to treat major depressive disorder (MDD). They may also be prescribed for the management of nocturnal enuresis (bedwetting), panic disorder, and certain chronic pain syndromes, although this use is off label.

  1. How long does it take for Imipramine to start working for depression?

It may take several weeks of consistent use for individuals to experience significant improvements in mood and relief from depressive symptoms. It’s important to continue taking the medication as prescribed, even if benefits are not immediately apparent.

  1. Can Imipramine HCl Tablets be used in children with bedwetting issues?

Yes, Imipramine is commonly prescribed for children who experience bedwetting (nocturnal enuresis). It can help reduce the frequency of bedwetting episodes, but its use should be closely monitored by a healthcare provider.

  1. What are the common side effects of Imipramine HCl Tablets?

Common side effects may include dry mouth, constipation, blurred vision, drowsiness, and dizziness. These side effects are usually mild and may improve with time.

  1. Can Imipramine be used during pregnancy or breastfeeding?

The use of Imipramine during pregnancy or breastfeeding should be discussed with a healthcare provider. The potential risks and benefits should be carefully considered.

  1. Are there any interactions with other medications or substances?

Imipramine may interact with certain medications, so it’s important to inform your healthcare provider about all the medications, including over-the-counter drugs and supplements, that you are taking to avoid potential interactions.

  1. Is it safe to abruptly stop taking Imipramine HCl Tablets?

Abruptly discontinuing Imipramine can lead to withdrawal symptoms. It’s important to follow your healthcare provider’s guidance and taper the dosage gradually if you decide to stop taking the medication.

  1. How often should I have follow-up appointments while taking Imipramine?

Regular followup appointments with your healthcare provider are important to monitor your progress, assess the effectiveness of the medication, and address any side effects or concerns.

  1. What should I do if I experience serious side effects or allergic reactions while taking Imipramine?

If you experience serious side effects or signs of an allergic reaction, such as difficulty breathing or swelling of the face, seek immediate medical attention. It’s essential to report any adverse reactions to your healthcare provider.

As Imipramine HCl Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Imipramine HCl Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Imipramine HCl Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Imipramine HCl Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

a) Imipramine HCl Tablets USP10mg
b) Imipramine HCl Tablets USP 25mg
c) Imipramine HCl Tablets USP 50mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

a) Imipramine HCl Tablets USP 10mg
Each film coated tablet contains:
Imipramine Hydrochloride USP……………….10mg
Excipients……………………………………………. q.s.
Colour: Tartarazine

b) Imipramine HCl Tablets USP 25mg
Each film coated tablet contains:
Imipramine Hydrochloride USP……………….25mg
Excipients……………………………………………. q.s.
Colour: Carmoisine Lake


c) Imipramine HCl Tablets USP 50mg
Each film coated tablet contains:
Imipramine Hydrochloride USP……………….50mg
Excipients…………………………………………. q.s.
Colour: Yellow Iron Oxide

THERAPEUTIC INDICATIONS:

This medication is used to treat depression. it is also used with other therapies for the treatment of night time bed-wetting (enuresis) in children. using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.

CAUTION & WARNING:

CAUTION:
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store below 25°C in a dry place. Do not freeze. Keep the container tightly closed in order to protect from moisture.
Dosage: As directed by the Physician.
Attach dispensing label as per end country.