Human Normal Albumin BP 20% (Aizen Life)

Human Normal Albumin BP 20% (Aizen Life) Technical Specification:

GENERIC NAME OF THE MEDICINAL PRODUCT:

• Human Normal Albumin BP 20%

QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Human Normal Albumin BP 20%
  Each vial contains:
  Total protein……………………200 g/Lit
  Sodium Caprylate…………….6.65 g/Lit
  Na+…. Not more than 160 mmol/Lit
  K+…….Not more than 2 mmol/Lit
  Aluminium……………………… ≤ 200 μg/Lit

THERAPEUTIC INDICATIONS:

HUMAN ALBUMIN is used to treat blood volume loss. It works by replacing the body fluids lost due to excessive trauma, bleeding, surgery, or kidney dialysis. Thus, it is helpful in treating low blood albumin levels.

CAUTION & WARNING:

Caution: It is dangerous to take this preparation except under medical supervision.

Warning: To be sold by retail on the prescription of the Registered Medical pharmacist only.

Active substance: human albumin

Source: Human plasma

Non-reactive for HBsAg, HCV, HIV antibodies and negative for HBV DNA, HIV RNA and HCV RNA by PCR.

Contains no preservatives.

Do not use if the solution is cloudy or turbid or if deposits have formed or if any particulate matters observed.

Contents must not be used more than four hours after the container has been penetrated and any remaining portion must be discarded.

Irrespective of blood groups, can be transferred to all recipients.

For Indication, caution, Dosage & Method of Administration please refer accompanying package insert.

Keep out of reach and sight of children.

STORAGE & DOSAGE:

Storage: Store the container between 2°C to 25°C. Do not freeze. Protect from light.

Note: shelf life of 36 months when stored at room temperature (up to +25°C)

Dosage: As directed by the physician.

For Oral use. Read the package insert before use.

Why Taj Pharmaceuticals?

When considering a pharmaceutical company for a product like Human Normal Albumin BP, healthcare professionals and institutions assess several critical factors. Quality assurance stands as a top priority, with a focus on the company’s commitment to maintaining high standards in medication production, especially for biologics. Regulatory compliance is equally essential, ensuring that the company obtains the necessary approvals and certifications to meet strict safety and efficacy standards. The purity of products, particularly for albumin, cannot be compromised, necessitating advanced purification processes and stringent quality controls. Reliability in the supply chain and competitive pricing are also crucial to ensure a steady and cost-effective supply of Human Normal Albumin BP. Exceptional customer support, timely deliveries, and effective communication are highly valued, contributing to a positive experience for healthcare professionals and institutions. The company’s track record, reputation, and adherence to ethical business practices play a significant role in decision-making, as does a commitment to research and development for continuous improvement. Ultimately, the choice of a pharmaceutical supplier greatly influences patient care, safety, and the overall success of healthcare institutions.

What is Human Normal Albumin BP and its uses?

Human Normal Albumin BP, also known simply as albumin, refers to a sterile solution of human albumin in a specific concentration that complies with the British Pharmacopoeia (BP) standards. It is a pharmaceutical product made from human plasma and is used for various medical purposes. Here are its primary uses:

• Plasma Volume Expander: Human Normal Albumin BP is often used as a plasma volume expander in cases of hypovolemia or shock. Hypovolemia refers to a condition where there is a significant loss of blood or other fluids, leading to a decrease in blood volume. In such situations, administering albumin helps increase blood volume and improves tissue perfusion.
• Hypoproteinemia: Hypoproteinemia is a condition characterized by low levels of proteins, including albumin, in the blood. Human Normal Albumin BP can be used to treat this condition, especially when it is due to conditions like liver disease, kidney disease, or malnutrition.
• Burns and Trauma: In cases of severe burns or trauma, there can be a substantial loss of fluids and proteins from the bloodstream. Human Normal Albumin BP can be administered to help restore normal blood volume and protein levels.
• Nephrotic Syndrome: Nephrotic syndrome is a kidney disorder that can lead to the loss of proteins, including albumin, through the urine. Albumin replacement therapy may be used to manage this condition.
• Ascites: Ascites is the accumulation of fluid in the abdominal cavity, often seen in patients with liver cirrhosis or other liver diseases. Human Normal Albumin BP can be used to manage ascites by increasing oncotic pressure in the blood vessels and reducing the accumulation of fluid in the abdomen.
• Cardiopulmonary Bypass: During heart surgeries that require cardiopulmonary bypass, there can be a dilution of blood components. Albumin may be used to restore the blood’s colloid osmotic pressure and help maintain proper fluid balance.
• Hemodialysis: In some cases, albumin may be used during hemodialysis to help manage complications associated with chronic kidney disease and improve blood volume and composition.

It’s important to note that the use of Human Normal Albumin BP should be determined by a qualified healthcare professional based on the patient’s specific medical condition and needs. The product is typically administered intravenously (IV) and is available in various concentrations to suit different clinical situations. Albumin is a critical component of blood plasma, and its therapeutic use can help stabilize patients in a variety of medical scenarios.

How Does Human Normal Albumin BP work?

Human Normal Albumin BP works primarily by influencing the colloid osmotic pressure within the blood vessels and interstitial spaces. Here’s how it works:

1. Osmotic Pressure Regulation: Albumin is a protein found in the blood plasma, and it plays a crucial role in maintaining the osmotic pressure of the blood. Osmotic pressure refers to the force that draws fluid into the blood vessels from the surrounding tissues. Albumin has a high molecular weight and is a colloid, which means it contributes significantly to the colloid osmotic pressure (also known as oncotic pressure) within the bloodstream.
2. Fluid Balance: In the circulatory system, there is a balance between hydrostatic pressure (the force pushing fluid out of blood vessels) and colloid osmotic pressure (the force pulling fluid into blood vessels). Albumin primarily contributes to the colloid osmotic pressure, which opposes the outward movement of fluids from the blood vessels into the surrounding tissues. This helps maintain the proper distribution of fluids in the body.
3. Volume Expansion: When Human Normal Albumin BP is administered intravenously, it increases the concentration of albumin in the blood plasma. This increase in albumin concentration enhances the colloid osmotic pressure within the blood vessels. As a result, more fluid is drawn into the bloodstream from the interstitial spaces (the spaces between cells in tissues). This process leads to an expansion of the blood volume.
4. Edema Reduction: In conditions where there is an abnormal accumulation of fluid in the interstitial spaces, such as in cases of hypovolemia, burns, or certain kidney disorders, Human Normal Albumin BP can help reduce edema (swelling) by drawing excess fluid back into the bloodstream. This helps restore normal tissue perfusion and reduces swelling.
5. Hemodynamic Stability: Human Normal Albumin BP is also used to stabilize hemodynamics, especially during surgical procedures, cardiopulmonary bypass, and shock states. By increasing blood volume and maintaining proper colloid osmotic pressure, it helps ensure adequate tissue perfusion and organ function.

In summary, Human Normal Albumin BP works by increasing the colloid osmotic pressure in the blood, which helps regulate fluid balance, expand blood volume, reduce edema, and stabilize hemodynamics. Its therapeutic use is essential in various medical conditions to support proper fluid distribution and maintain vital organ function. However, the administration and dosage should always be determined by a healthcare professional based on the patient’s specific needs and medical condition.