Exemestane Tablets 25mg Technical Specification:

Product Name:Exemestane Tablets 25mg
Brand Name:Exemestane
Strength:25mg
Dosage Form:Film-coated Tablet
Packing:10s, 15s, 30s
Route of Administration:For Oral Use only.
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Cancer
Indication: Exemestane is used to treat early and advanced breast cancer in women who have already stopped menstruating (postmenopausal)
Storage:Store at 25°C (77° F); excursions permitted to 15°C to 30°C (59° to 86° F) [see USP Controlled Room Temperature].

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Exemestane Tablets 25mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Exemestane Tablets 25mg
    Each film-coated tablet contains:
    Exemestane……..……………….25mg
    Excipients………………………….q.s.
    Colours: Iron Oxide and Titanium Dioxide USP

THERAPEUTIC INDICATIONS:

Exemestane is used to treat early and advanced breast cancer in women who have already stopped menstruating (postmenopausal)

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.

WARNING: Cytotoxic Agent:  To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.

Swallow complete tablet, do not crush or chew.

Dispense in a tight, light resistant container.

Keep container tightly closed.

Dispense in original container.

Do not use if seal over bottle opening is broken or missing.

Keep out of reach and sight of children.

STORAGE & DOSAGE:

Storage: Store at 25°C (77° F); excursions permitted to 15°C to 30°C (59° to 86° F) [see USP Controlled Room Temperature].

Dosage: As directed by Oncologist.

For Oral use. Read the package insert before use.

Why Taj Pharmaceuticals?

When it comes to Exemestane Tablets, Taj Pharmaceuticals stands out as the go-to choice. With a rich history of pharmaceutical excellence, Taj Pharmaceuticals has earned a reputation for reliability and quality that you can trust. Our Exemestane Tablets are no exception, as we adhere to the highest industry standards in manufacturing and safety. At Taj Pharmaceuticals, affordability is a core value. We believe that access to essential medications should not be a financial burden. Our Exemestane Tablets offer both quality and cost-effectiveness, ensuring that patients receive the best care without breaking the bank. What sets us apart is our unwavering commitment to patient well-being. Taj Pharmaceuticals understands the importance of medication in improving the lives of those in need. We prioritize your health and strive to provide the highest quality Exemestane Tablets to support your treatment journey.

Choose Taj Pharmaceuticals for your Exemestane medication needs, and experience excellence in pharmaceuticals. Your health is our priority, and we are here to serve you with dedication and compassion. Trust in Taj Pharmaceuticals for the quality, affordability, and care you deserve.

What is Exemestane Tablets and its use?

Exemestane Tablets are a medication used in the treatment of breast cancer, specifically hormone receptor-positive breast cancer in postmenopausal women. Exemestane is classified as an aromatase inhibitor, a type of drug that works by reducing the levels of estrogen in the body. Estrogen can promote the growth of certain types of breast cancer, so by lowering estrogen levels, Exemestane helps slow down or stop the growth of cancer cells.

Here’s a brief overview of the primary use of Exemestane Tablets:

  • Breast Cancer Treatment: Exemestane is prescribed to postmenopausal women who have been diagnosed with hormone receptor-positive breast cancer. These tumors have receptors for hormones like estrogen, and they use estrogen to grow. Exemestane works by blocking the enzyme aromatase, which is responsible for converting other hormones into estrogen. By reducing estrogen levels in the body, Exemestane helps inhibit the growth of these cancer cells.

Exemestane is typically used after other treatments like surgery, radiation, or other hormonal therapies have been tried and found ineffective. It is often prescribed as a part of long-term treatment to prevent cancer recurrence. Exemestane Tablets are available by prescription only and should be taken under the guidance of a healthcare provider. It’s crucial for patients to discuss the potential benefits and risks of Exemestane with their healthcare team, as well as any potential side effects or interactions with other medications they may be taking.

How does Exemestane Tablets work?

Exemestane Tablets work by blocking the action of an enzyme called aromatase, which plays a crucial role in the production of estrogen in the body. Estrogen is a hormone that can stimulate the growth of hormone receptor-positive breast cancer cells. Exemestane is classified as an aromatase inhibitor, and its mechanism of action involves the following steps:

  • Estrogen Production: In postmenopausal women, the primary source of estrogen production is the conversion of androgens (male hormones) into estrogen through the action of the aromatase enzyme. Aromatase is found in various tissues, including adipose (fat) tissue and breast cancer cells.
  • Aromatase Inhibition: Exemestane works by binding to the aromatase enzyme and irreversibly inhibiting its activity. This means that once Exemestane has interacted with aromatase, the enzyme is permanently deactivated.
  • Reduction of Estrogen Levels: By inhibiting aromatase, Exemestane effectively reduces the production of estrogen in the body. Lower estrogen levels are beneficial in the treatment of hormone receptor-positive breast cancer because these cancer cells rely on estrogen to grow and proliferate.
  • Inhibition of Cancer Growth: With reduced estrogen levels, the estrogen-dependent breast cancer cells are deprived of their growth stimulus. This can slow down or stop the progression of the cancer, as the cancer cells are no longer receiving the signals they need to multiply.

Exemestane is typically prescribed to postmenopausal women because their ovaries have stopped producing estrogen. In premenopausal women, the ovaries are the primary source of estrogen production, so a different type of medication, such as a selective estrogen receptor modulator (SERM), is usually used to block the effects of estrogen.

Benefits of Exemestane Tablets:

  • Treatment of Hormone ReceptorPositive Breast Cancer: Exemestane Tablets are primarily used to treat postmenopausal women with hormone receptorpositive breast cancer. By reducing estrogen levels in the body, Exemestane helps slow down or stop the growth of cancer cells dependent on estrogen.
  • Reduction in Cancer Recurrence Risk: Exemestane is often prescribed as adjuvant therapy after initial treatments like surgery or radiation to reduce the risk of cancer recurrence. It can help improve longterm outcomes for breast cancer patients.
  • WellTolerated: Exemestane is generally welltolerated by many patients, with manageable side effects compared to some other breast cancer treatments.

Side Effects of Exemestane Tablets:

  • Hot Flashes: Many women experience hot flashes while taking Exemestane.
  • Fatigue: Some patients may experience increased tiredness.
  • Joint and Muscle Pain: Musculoskeletal pain, including joint and muscle pain, can occur.
  • Bone Density Loss: Exemestane can lead to bone density loss, which may increase the risk of osteoporosis and fractures. Regular bone density monitoring and supplementation with calcium and vitamin D may be recommended.
  • Nausea and Vomiting: Some individuals may experience nausea or vomiting.
  • Headache: Headaches are a less common side effect.
  • Insomnia: Difficulty sleeping can occur in some patients.
  • Allergic Reactions: Although rare, severe allergic reactions can occur. Seek immediate medical attention if you experience symptoms like rash, itching, swelling, severe dizziness, or trouble breathing.
  • Liver Problems: Serious liver problems are rare but possible. Report any signs of liver issues, such as yellowing of the skin or eyes, dark urine, or persistent nausea.
  • Impact on Cholesterol Levels: Exemestane may lead to increased levels of cholesterol in some individuals. Regular monitoring of cholesterol levels may be necessary.

Frequently asked questions (FAQs) about Exemestane Tablets:

  1. What are Exemestane Tablets used for?

Exemestane Tablets are primarily used in the treatment of hormone receptorpositive breast cancer in postmenopausal women. They help reduce estrogen levels in the body to slow down or stop the growth of cancer cells dependent on estrogen.

  1. How do Exemestane Tablets work?

Exemestane works by inhibiting the aromatase enzyme, which is responsible for converting other hormones into estrogen. By reducing estrogen production, Exemestane hinders the growth of estrogendependent breast cancer cells.

  1. Who can take Exemestane Tablets?

Exemestane is typically prescribed to postmenopausal women with hormone receptorpositive breast cancer. It is not suitable for premenopausal women as their ovaries are the primary source of estrogen production.

  1. What are the common side effects of Exemestane Tablets?

Common side effects include hot flashes, fatigue, joint and muscle pain, and bone density loss. Other less common side effects may include nausea, vomiting, headache, and insomnia. Patients should discuss any side effects with their healthcare provider.

  1. Are there any serious side effects associated with Exemestane?

While serious side effects are rare, they can include severe allergic reactions and liver problems. Patients should seek immediate medical attention if they experience symptoms like rash, swelling, yellowing of the skin or eyes, dark urine, or persistent nausea.

  1. How should Exemestane Tablets be taken?

Exemestane is usually taken once daily, often with food. Patients should follow their healthcare provider’s instructions carefully and not adjust the dosage without consulting a healthcare professional.

  1. Can Exemestane Tablets be used during pregnancy or while breastfeeding?

Exemestane is not recommended during pregnancy as it can harm the developing fetus. It should not be used while breastfeeding either, as it may pass into breast milk and harm the nursing infant.

  1. Are there any drug interactions with Exemestane?

Exemestane can interact with certain medications, so it’s crucial to inform your healthcare provider about all the medications and supplements you are taking. This includes hormone replacement therapy, estrogencontaining products, and other medications that affect estrogen levels.

  1. How long do I need to take Exemestane Tablets?

The duration of Exemestane treatment varies depending on the individual’s specific breast cancer diagnosis and treatment plan. It is often prescribed as part of longterm adjuvant therapy to reduce the risk of cancer recurrence.

  1. What should I do if I miss a dose of Exemestane?

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

As Exemestane Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Exemestane Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Exemestane Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Exemestane Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

Exemestane Tablets 25mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Exemestane Tablets 25mg
Each film-coated tablet contains:
Exemestane……..……………….25mg
Excipients………………………….q.s.
Colours: Iron Oxide and Titanium Dioxide USP

THERAPEUTIC INDICATIONS:

Exemestane is used to treat early and advanced breast cancer in women who have already stopped menstruating (postmenopausal)

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.
WARNING: Cytotoxic Agent: To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.
Swallow complete tablet, do not crush or chew.
Dispense in a tight, light resistant container.
Keep container tightly closed.
Dispense in original container.
Do not use if seal over bottle opening is broken or missing.
Keep out of reach and sight of children.

STORAGE & DOSAGE:

Storage: Store at 25°C (77° F); excursions permitted to 15°C to 30°C (59° to 86° F) [see USP Controlled Room Temperature].
Dosage: As directed by Oncologist.
For Oral use. Read the package insert before use.