Etoposide Capsules USP 100mg

Etoposide Capsules USP 100mg Technical Specification:

Product Name:Etoposide Capsules USP 100mg
Brand Name:Generics
Strength:50mg, 100mg
Dosage Form:Hard-Gelatin Capsules
Packing:4s, 12s, 8s, 20s
Route of Administration:For Oral Use only.
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Cancer
Indication: Etoposide is used in combination with other medications to treat a certain type of lung cancer (small cell lung cancer; SCLC).
Storage:Store at 25°C (77° F); excursions permitted to 15° C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature]. Protect from light. Do not refrigerate.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Etoposide Capsules USP 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Etoposide Capsules USP 100mg
    Each capsule contains:
    Etoposide USP………………100mg
    Excipients……………………..q.s.
    Colours: Approved colours used in capsule shell

THERAPEUTIC INDICATIONS:

Etoposide is used in combination with other medications to treat a certain type of lung cancer (small cell lung cancer; SCLC).

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.

WARNING: Cytotoxic Agent: To be sold by retail on the prescription of Oncologist/ Cancer Hospital/ Institution only.

WARNING: To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.

ETOPOSIDE IS AN ANTI-NEOPLASTIC DRUG FOR INTRAVENOUS OR ORAL USE, WHICH CAN BE USED ALONE OR IN COMBINATION WITH OTHER ONCOLYTIC DRUGS.

Swallow capsules whole. Do not chew, dissolve or open the capsules.

Keep out of reach and sight of children.

STORAGE & DOSAGE:

Storage: Store at 25°C (77° F); excursions permitted to 15° C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].

Protect from light. Do not refrigerate.

Dosage: As directed by Oncologist.

For Oral use. Read the package insert before use.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals, a reputable pharmaceutical company, offers Etoposide Capsules USP among its diverse product portfolio. One of the key reasons to consider Taj Pharmaceuticals for Etoposide Capsules USP is their unwavering commitment to quality assurance. The pharmaceutical industry demands strict adherence to quality standards, and Taj Pharmaceuticals has a track record of meeting these standards, ensuring that their products meet safety and efficacy requirements consistently. In addition to quality, regulatory compliance is paramount in the pharmaceutical sector. Taj Pharmaceuticals is known for its rigorous compliance with regulatory agencies such as the U.S. Food and Drug Administration (FDA) or similar authorities in different countries. This compliance assures healthcare professionals and patients that the product they are receiving meets the highest safety and effectiveness standards.

A reliable supply chain is another significant factor in choosing Taj Pharmaceuticals. The availability and accessibility of Etoposide Capsules USP are crucial for healthcare institutions and patients who rely on this medication for the treatment of various medical conditions. Taj Pharmaceuticals’ well-established distribution network ensures that their pharmaceutical products, including Etoposide Capsules USP, are readily accessible. Competitive pricing is often a consideration in healthcare procurement, and Taj Pharmaceuticals may offer cost-effective solutions for Etoposide Capsules USP without compromising quality. This affordability can make them an appealing choice for healthcare providers and institutions seeking to optimize their budgets.

The reputation of a pharmaceutical company matters significantly in healthcare decision-making. Taj Pharmaceuticals has built a strong reputation over the years for delivering high-quality products and maintaining consistent supply. This reputation can instill confidence in healthcare professionals and institutions when choosing a supplier for critical medications like Etoposide Capsules USP. Furthermore, Taj Pharmaceuticals’ geographic coverage aligns with the distribution needs of many regions, ensuring that healthcare providers can access their products promptly and efficiently. Collaborations and partnerships with healthcare institutions and professionals may also enhance the value proposition of Taj Pharmaceuticals, offering additional support and resources to users of their products. In conclusion, the decision to choose Taj Pharmaceuticals for Etoposide Capsules USP should involve a thorough assessment of specific needs, compliance requirements, pricing considerations, and the company’s reputation for quality and reliability. Consulting with healthcare experts and conducting comprehensive due diligence can aid in making an informed decision that benefits both healthcare providers and patients.

What is Etoposide Capsules USP and their Uses:

Etoposide Capsules USP, or simply Etoposide, is a medication used in the treatment of various types of cancer. It belongs to a class of drugs called topoisomerase inhibitors, which work by interfering with the DNA in cancer cells, ultimately preventing their growth and replication. Here are some common uses of Etoposide Capsules USP:

  • Small Cell Lung Cancer (SCLC): Etoposide is frequently used in combination with other chemotherapy drugs to treat small cell lung cancer, a type of lung cancer that tends to grow and spread quickly.
  • Testicular Cancer: Etoposide is also used in the treatment of testicular cancer. It may be administered alone or in combination with other chemotherapy drugs, depending on the specific diagnosis and stage of the cancer.
  • Non-Hodgkin Lymphoma (NHL): Etoposide can be part of a chemotherapy regimen for some forms of non-Hodgkin lymphoma, a cancer that affects the lymphatic system.
  • Hodgkin Lymphoma: In the treatment of Hodgkin lymphoma, Etoposide may be used in combination with other chemotherapy agents, particularly in cases where the disease has relapsed or proved resistant to initial treatments.
  • Leukemia: Etoposide may be considered in the treatment of certain types of leukemia, particularly acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).
  • Neuroblastoma: Etoposide is used in the treatment of neuroblastoma, a cancer that primarily affects young children.
  • Ovarian Cancer: Etoposide may be used in the management of ovarian cancer, often as part of a combination chemotherapy regimen.
  • Other Cancers: In some cases, Etoposide may be prescribed for other types of cancer, either alone or in combination with other drugs, depending on the specific diagnosis and treatment plan.

It’s essential to note that the use of Etoposide Capsules USP is determined by the type of cancer, its stage, and the patient’s overall health. Treatment with Etoposide is typically administered by healthcare professionals in a clinical setting, and the dosages and schedules can vary depending on the specific cancer being treated. As with any cancer treatment, the potential benefits and risks of Etoposide should be discussed thoroughly with an oncologist or healthcare provider.

How does Etoposide Capsules USP Work:

Etoposide is a medication used in the treatment of various types of cancer, including lung cancer, testicular cancer, and certain forms of leukemia and lymphoma. Taj Pharma’s Etoposide Capsules USP contain the active ingredient etoposide and are used for their cytotoxic (cell-killing) properties against cancer cells. Here’s how etoposide works:

  • Inhibition of Topoisomerase II: Etoposide primarily exerts its anti-cancer effects by interfering with the activity of an enzyme called topoisomerase II. Topoisomerase II is responsible for managing the structure and winding of DNA strands during cell division. It helps break and reseal the DNA strands to facilitate necessary genetic processes. Etoposide inhibits this enzyme by binding to it and trapping it in a complex with DNA. As a result, it prevents the enzyme from resealing the broken DNA strands.
  • DNA Damage: The inhibition of topoisomerase II by etoposide leads to the accumulation of DNA strand breaks in cancer cells. These breaks cannot be repaired by the cell’s repair machinery because etoposide prevents topoisomerase II from completing its normal function. As a result, the DNA damage accumulates and becomes lethal to the cancer cells.
  • Cell Cycle Arrest: The accumulation of DNA damage triggers the activation of cell cycle checkpoints. Cells with damaged DNA typically arrest their progression through the cell cycle to allow time for DNA repair. However, etoposide-induced DNA damage is extensive and difficult to repair, leading to prolonged cell cycle arrest.
  • Apoptosis: If the DNA damage is too severe and cannot be repaired, the cell may undergo programmed cell death, known as apoptosis. Etoposide-induced DNA damage often pushes cancer cells toward apoptosis, leading to the death of these abnormal cells.

By interfering with DNA structure and function and promoting DNA damage and cell cycle arrest, Taj Pharma’s Etoposide Capsules USP ultimately works to inhibit the growth and proliferation of cancer cells. It is important to note that etoposide is generally used as part of combination chemotherapy regimens, where it is combined with other anti-cancer drugs to enhance its effectiveness in treating specific types of cancer. The exact treatment plan and dosage of etoposide will depend on the type and stage of cancer being treated, as well as individual patient factors, and should be determined by a qualified oncologist.

Benefits of Etoposide Capsules:

  • Effective Against Various Cancers: Etoposide is used to treat a wide range of cancers, including lung cancer, testicular cancer, ovarian cancer, leukemia, lymphoma, and others. Its versatility makes it a valuable component of many cancer treatment regimens.
  • Tumor Reduction: Etoposide can shrink tumors, making them more manageable for surgical removal or other treatments. This can improve a patient’s quality of life and potentially increase the success of curative interventions.
  • Combination Therapy: Etoposide is often used in combination with other chemotherapy drugs. This approach, known as combination therapy, can enhance the effectiveness of cancer treatment by targeting cancer cells through multiple mechanisms.
  • High Response Rates: In some cases, etoposide has demonstrated high response rates, leading to partial or complete remission in cancer patients. This can significantly extend a patient’s life and improve their prognosis.
  • Preventing Cancer Spread: Etoposide can help prevent the spread of cancer cells to other parts of the body. This is crucial in controlling the progression of the disease and reducing the risk of metastasis.
  • Neoadjuvant Therapy: Etoposide may be used as part of neoadjuvant therapy, which is given before surgery or radiation therapy to shrink tumors and make them more amenable to other treatments.
  • Adjuvant Therapy: After surgery or other primary cancer treatments, etoposide may be used as adjuvant therapy to eliminate any remaining cancer cells and reduce the risk of cancer recurrence.
  • Palliative Care: In cases where a cure is not possible, etoposide can provide palliative care, relieving cancer-related symptoms and improving a patient’s quality of life.

It’s important to note that the benefits of etoposide treatment should be carefully weighed against potential side effects and individual patient factors. The use of etoposide should be guided by a qualified oncologist who can tailor the treatment plan to the patient’s specific diagnosis and needs. Additionally, discussions about the potential benefits and risks of etoposide should be part of the informed consent process, allowing patients to make well-informed decisions about their cancer treatment.

Side Effects of Etoposide Capsules:

  • Bone Marrow Suppression: Etoposide can suppress the bone marrow’s ability to produce blood cells, including white blood cells, red blood cells, and platelets. This can lead to an increased risk of infection (due to low white blood cell count), anemia (due to low red blood cell count), and bleeding or bruising (due to low platelet count).
  • Nausea and Vomiting: Nausea and vomiting are common side effects of etoposide treatment. Medications to manage these symptoms are often prescribed alongside etoposide.
  • Hair Loss: Many cancer patients undergoing etoposide treatment may experience hair loss (alopecia). This is usually temporary, and hair typically regrows after treatment is completed.
  • Fatigue: Cancer-related fatigue is common and can be exacerbated by etoposide treatment. Patients may experience tiredness and weakness.
  • Gastrointestinal Issues: Etoposide can cause diarrhea and mouth sores in some patients.
  • Hypotension: Low blood pressure (hypotension) is a potential side effect, and it may occur during or after treatment with etoposide.
  • Allergic Reactions: While rare, some individuals may experience allergic reactions to etoposide, which can manifest as rash, itching, swelling, or difficulty breathing.
  • Secondary Cancers: There is a small risk of developing secondary cancers, such as leukemia, as a result of etoposide treatment, particularly when used in combination with other chemotherapy drugs.

It’s essential for patients to be closely monitored by their healthcare providers during etoposide treatment to manage and minimize these side effects. Dosage and treatment regimens are adjusted based on the patient’s specific condition and response to the medication. Patients and their healthcare teams should have open communication about the potential benefits and risks of etoposide treatment, and patients should report any side effects promptly to ensure appropriate management and support during their cancer treatment journey.

Frequently Asked Questions About Etoposide Capsules:

Certainly, here are some frequently asked questions about Etoposide Capsules (etoposide) and their answers:

  • What are Etoposide Capsules used for?

Etoposide Capsules are used in the treatment of various types of cancer, including lung cancer, testicular cancer, ovarian cancer, leukemia, and lymphoma.

  • How do Etoposide Capsules work?

Etoposide inhibits an enzyme called topoisomerase II, which is involved in DNA replication and repair. By interfering with this enzyme, it causes DNA damage and disrupts the growth and division of cancer cells.

  • Are etoposide Capsules a cure for cancer?

Etoposide is not a cure for cancer on its own. It is typically used as part of combination chemotherapy regimens or in conjunction with other cancer treatments to improve the chances of remission or control the disease.

  • How are Etoposide Capsules administered?

Etoposide is usually taken orally in the form of capsules, as prescribed by a healthcare provider. The dosage and treatment schedule will be determined by your oncologist based on your specific cancer type and stage.

  • What are the common side effects of Etoposide Capsules?

Common side effects can include nausea, vomiting, hair loss, fatigue, bone marrow suppression (leading to low blood cell counts), diarrhea, and mouth sores. These side effects should be discussed with your healthcare team.

  • How should I manage nausea and vomiting while taking Etoposide Capsules?

Your healthcare provider may prescribe antinausea medications to help manage these side effects. It’s essential to follow their recommendations and let them know if the nausea and vomiting are severe.

  • Can I drink alcohol while taking Etoposide Capsules?

It’s generally recommended to avoid alcohol during cancer treatment, as it can interact with medications and may exacerbate side effects. Discuss alcohol consumption with your healthcare provider.

  • How often will I need to have blood tests during Etoposide treatment?

Regular blood tests are typically performed during Etoposide treatment to monitor blood cell counts and assess how your body is responding to the medication. The frequency of these tests will be determined by your healthcare team.

  • What precautions should I take during Etoposide treatment?

It’s crucial to follow your healthcare provider’s instructions carefully. Be vigilant about infection prevention, maintain good hand hygiene, and avoid close contact with sick individuals due to the increased risk of infection during treatment.

  • Can I continue working and leading a normal life while taking Etoposide Capsules?

The ability to work and lead a normal life during Etoposide treatment will depend on your individual response to the medication, the type and stage of cancer, and the severity of side effects. It’s important to discuss your daily activities and any limitations with your healthcare team, as they can provide guidance and support.

Remember that these are general FAQs, and individual circumstances may vary. It’s crucial to have open and regular communication with your healthcare provider throughout your Etoposide treatment to address any questions or concerns you may have and to ensure the best possible outcome in your cancer therapy.

As Etoposide Capsules Exporters; We can cater to export business queries from the following geographies. We are exporting our Etoposide Capsules product to the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Etoposide Capsules Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Etoposide Capsules, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

a) Etoposide Capsules USP 50mg
b) Etoposide Capsules USP 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

a) Etoposide Capsules USP 50mg
Each capsule contains:
Etoposide USP………………50mg
Excipients……………………..q.s.
Colours: Approved colours used in capsule shell

b) Etoposide Capsules USP 100mg
Each capsule contains:
Etoposide USP………………100mg
Excipients……………………..q.s.
Colours: Approved colours used in capsule shell


THERAPEUTIC INDICATIONS:

Etoposide is used in combination with other medications to treat a certain type of lung cancer (small cell lung cancer; SCLC).

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.
WARNING: Cytotoxic Agent: To be sold by retail on the prescription of Oncologist/ Cancer Hospital/ Institution only.
WARNING: To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.
ETOPOSIDE IS AN ANTI-NEOPLASTIC DRUG FOR INTRAVENOUS OR ORAL USE, WHICH CAN BE USED ALONE OR IN COMBINATION WITH OTHER ONCOLYTIC DRUGS.
Swallow capsules whole. Do not chew, dissolve or open the capsules.
Keep out of reach and sight of children.

STORAGE & DOSAGE:

Storage: Store at 25°C (77° F); excursions permitted to 15° C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].
Protect from light. Do not refrigerate.
Dosage: As directed by Oncologist.
For Oral use. Read the package insert before use.

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