Esomeprazole EC & Domperidone SR Capsule 40mg/30mg (Esotaj-DSR)

Esomeprazole EC & Domperidone SR Capsule 40mg/30mg Technical Specification:

GENERIC NAME OF THE MEDICINAL PRODUCT:

• Esomeprazole EC & Domperidone SR Capsule 40mg/30mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Esomeprazole EC & Domperidone SR Capsule 40mg/30mg
  Each Hard-gelatin capsules contains:
  Esomeprazole Magnesium Trihydrate
  Eq. to Esomeprazole Magnesium I.P. ………40mg
  (As enteric coated pellets)
  Domperidone I.P. ……………………………….30mg
  (As sustain release pellets)
  Excipients ………………………………………… q.s.
  Approved colours used in the empty capsule shell.

THERAPEUTIC INDICATIONS:

Esomeprazole + Domperidone is a combination of two medicines: Domperidone and Pantoprazole. This combination is used to treat acidity, heartburn or Gastroesophageal Reflux Disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus).

CAUTION & schedule:

CAUTION:  SWALLOW WHOLE DO NOT CHEW OR CRUSH

They should be swallowed whole with water.

Read enclosed leaflet before use.

schedule: schedule H PRESCRIPTION DRUG-CAUTION:  To be sold by retail on the prescription of a Registered Medical Practitioner only.

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage:  Store below 25°C in a dry place.  Do not freeze.  Keep the container tightly closed in order to protect from moisture.

Dosage:  As directed by the physician.

Why Taj Pharmaceuticals?

At Taj Pharma, we take pride in delivering pharmaceutical solutions that prioritize your well-being. Our Esomeprazole EC & Domperidone SR Capsule is no exception. With a commitment to excellence and a legacy of trust, we have developed a product that addresses your gastrointestinal concerns with precision and care. Our Esomeprazole EC & Domperidone SR Capsule combines the potency of Esomeprazole, a proton pump inhibitor, with the effectiveness of Domperidone, a prokinetic agent. This unique formulation not only provides relief from acid reflux and heartburn but also aids in regulating gastric motility, ensuring a comprehensive approach to managing gastrointestinal issues. Quality is at the heart of everything we do at Taj Pharma. We adhere to stringent quality control standards and use state-of-the-art manufacturing processes to create pharmaceuticals you can rely on. When you choose Taj Pharma, you’re choosing a trusted partner in your journey towards better health.

Experience the difference with Taj Pharma’s Esomeprazole EC & Domperidone SR Capsule, and regain control over your digestive health. Join the countless individuals who have entrusted us with their well-being, and discover why Taj Pharma is the preferred choice for Esomeprazole and Domperidone formulations.

What is Esomeprazole EC & Domperidone SR Capsule and its use?

Esomeprazole EC & Domperidone SR Capsule is a pharmaceutical medication that combines two active ingredients: Esomeprazole and Domperidone. Each of these ingredients serves a specific purpose in addressing gastrointestinal issues. Here’s a breakdown of the components and their uses:

Esomeprazole (EC):

• Esomeprazole is a proton pump inhibitor (PPI), which means it reduces the production of stomach acid.
• It is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), also known as acid reflux. GERD can cause symptoms like heartburn, regurgitation, and indigestion.
• Esomeprazole helps alleviate these symptoms by decreasing the amount of acid the stomach produces, which can help in healing and preventing damage to the esophagus caused by stomach acid.

Domperidone (SR):

• Domperidone is a prokinetic agent that helps regulate gastrointestinal motility. It works by increasing the movement of food and fluids through the stomach and intestines.
• This medication is used to relieve symptoms such as nausea, vomiting, bloating, and discomfort caused by conditions like gastroparesis (slow emptying of the stomach) and functional dyspepsia (indigestion).
• Domperidone can also be used to prevent or manage nausea and vomiting associated with certain medications or conditions.

The combination of Esomeprazole and Domperidone in a single capsule is often prescribed when a patient has both acid-related issues (like GERD) and associated symptoms like nausea or slow stomach emptying. This combination can help provide comprehensive relief for individuals experiencing these overlapping gastrointestinal symptoms.

How does Esomeprazole EC & Domperidone SR Capsule work?

Esomeprazole EC & Domperidone SR Capsules work through the combined actions of their two active ingredients: Esomeprazole and Domperidone. Let’s explore how each of these components functions:

Esomeprazole (EC):

• Esomeprazole is a proton pump inhibitor (PPI). PPIs are medications that target the proton pumps in the stomach’s lining cells.
• Proton pumps are responsible for producing stomach acid. When they are inhibited by Esomeprazole, the production of gastric acid is significantly reduced.
• By reducing stomach acid production, Esomeprazole helps alleviate symptoms of conditions like gastroesophageal reflux disease (GERD), which include heartburn, acid regurgitation, and esophageal irritation.
• Esomeprazole’s action is particularly important for healing and preventing damage to the esophagus caused by excessive acid exposure.

Domperidone (SR):

• Domperidone is a prokinetic agent that acts on the digestive system’s motility.
• It works by blocking the action of a neurotransmitter called dopamine in the gastrointestinal tract. This results in increased contractions of the muscles in the stomach and upper small intestine.
• By enhancing gastrointestinal motility, Domperidone helps food and stomach contents move through the digestive system more efficiently.
• Domperidone is often used to relieve symptoms of conditions such as gastroparesis (delayed stomach emptying) and functional dyspepsia, which can include symptoms like nausea, vomiting, bloating, and discomfort.

In combination, Esomeprazole and Domperidone address a broader range of gastrointestinal issues. Esomeprazole reduces excess stomach acid production, which can contribute to acid-related problems like GERD, while Domperidone promotes proper stomach emptying and alleviates symptoms like nausea and indigestion.

Benefits and Side effects of Esomeprazole EC & Domperidone SR Capsule:

Esomeprazole EC & Domperidone SR Capsules offer several potential benefits in managing gastrointestinal conditions, particularly when prescribed by a healthcare professional. However, like any medication, they may also have side effects. Here’s an overview of the potential benefits and side effects:

Benefits:

• Relief from Acid-Related Disorders: These capsules are commonly prescribed to manage acid-related conditions such as gastroesophageal reflux disease (GERD). Esomeprazole reduces stomach acid production, providing relief from symptoms like heartburn, acid regurgitation, and esophageal irritation.
• Enhanced Gastric Motility: Domperidone, a prokinetic agent, promotes the proper movement of food and fluids through the stomach and intestines. This can help relieve symptoms associated with delayed stomach emptying, such as nausea, vomiting, bloating, and discomfort.
• Comprehensive Symptom Relief: The combination of Esomeprazole and Domperidone addresses both acid-related issues and associated symptoms like nausea. This provides comprehensive relief for individuals with overlapping gastrointestinal symptoms.

Side Effects:

It’s essential to note that not everyone will experience side effects, and the severity and frequency of side effects can vary from person to person. Common side effects associated with Esomeprazole EC & Domperidone SR Capsules may include:

• Nausea and Vomiting: Ironically, while Domperidone is used to relieve nausea in some cases, it may also cause nausea as a side effect in some individuals.
• Headache: Some people may experience headaches while taking these capsules.
• Diarrhea or Constipation: Changes in bowel habits, such as diarrhea or constipation, can occur in a small percentage of users.
• Abdominal Discomfort: Mild abdominal discomfort or pain may occur in some cases.
• Dizziness: Domperidone can rarely cause dizziness or ligh the adedness.
• Allergic Reactions: Although rare, allergic reactions to any medication are possible. If you experience symptoms such as itching, rash, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
• Rare but Serious Side Effects: In very rare cases, Esomeprazole may be associated with more serious side effects, such as bone fractures, low magnesium levels, and certain infections.

Frequently asked questions about Esomeprazole EC & Domperidone SR Capsule:

Certainly, here are some frequently asked questions (FAQs) about Esomeprazole EC & Domperidone SR Capsules:

1. What is Esomeprazole EC & Domperidone SR Capsule used for?

Esomeprazole EC & Domperidone SR Capsules are commonly used to treat acidrelated conditions such as gastroesophageal reflux disease (GERD) and associated symptoms like heartburn, acid regurgitation, and nausea. Domperidone in the capsule also aids in regulating gastric motility.

2. How does Esomeprazole EC & Domperidone SR Capsule work?

Esomeprazole reduces stomach acid production by inhibiting proton pumps, while Domperidone enhances gastrointestinal motility. Together, they provide relief from acidrelated symptoms and promote proper stomach emptying.

3. What is the recommended dosage for these capsules?

The dosage can vary depending on the specific condition being treated and individual patient factors. It is crucial to follow the dosage instructions provided by your healthcare provider.

4. Are there any potential side effects?

Yes, like any medication, Esomeprazole EC & Domperidone SR Capsules may have side effects. Common side effects may include nausea, headache, diarrhea or constipation, abdominal discomfort, and dizziness. It’s essential to report any severe or unusual side effects to your healthcare provider.

5. Can I take Esomeprazole EC & Domperidone SR Capsules with other medications?

It’s important to inform your healthcare provider about all the medications and supplements you are taking to ensure there are no potential interactions. Some medications may interact with Esomeprazole or Domperidone, affecting their effectiveness or causing side effects.

6. How long should I take these capsules?

The duration of treatment varies depending on your condition and the advice of your healthcare provider. It’s essential to complete the prescribed course of treatment even if your symptoms improve.

7. Can I drink alcohol while taking these capsules?

It’s generally recommended to limit alcohol consumption while taking these capsules, as alcohol can exacerbate some gastrointestinal issues and may interact with the medication.

8. Are there any dietary restrictions or recommendations when taking Esomeprazole EC & Domperidone SR Capsules?

Your healthcare provider may provide dietary guidance based on your condition. In general, it’s advisable to avoid spicy, acidic, or fatty foods that can trigger acid reflux and worsen symptoms.

9. Can pregnant or breastfeeding individuals take these capsules?

It’s important to consult a healthcare provider before using these capsules during pregnancy or while breastfeeding, as there may be potential risks or alternatives to consider.

10. What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses.

As Esomeprazole EC & Domperidone SR Capsule Exporters; We can cater to export business queries from the following geographies. We are exporting our Esomeprazole EC & Domperidone SR Capsule product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Esomeprazole EC & Domperidone SR Capsule Regulatory Documents:

• Certificate of Analysis (COA)
• Method of Analysis (MOA)
• Stability Data (Accelerated stability / Long-term stability / Zone 4b)
• CTD Dossier / ACTD Dossiers / eCTD Dossiers
• Certificate of Pharmaceuticals Product (COPP)
• Free Sale Certificate (FSC)

Contact the most reliable manufacturer of Esomeprazole EC & Domperidone SR Capsule, Taj Pharmaceuticals Limited to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274