Diethylstilbestrol Tablets USP 5mg Taj Pharma


A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. Stilbestrol Tablet is used for Postpartum lactation suppression, Atrophic vaginitis, Gonorrheal vaginitis, Menopausal symptoms and other conditions. Stilbestrol Tablet may also be used for Prostate Cancer. Stilbestrol Tablet contains Diethylstilbestrol as an active ingredient.

Stilbestrol Tablet works by interacting with a protein receptor.


Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.


Diethylstilbestrol is a synthetic estrogen that was developed to supplement a woman’s natural estrogen production. In 1971, the Food and Drug Administration (FDA) issued a Drug Bulletin advising physicians to stop prescribing DES to pregnant women because it was linked to a rare vaginal cancer in female offspring.

Mechanism of action

Estrogens diffuse into their target cells and interact with a protein receptor, the estrogen receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. The effect of Estrogen binding their receptors causes downstream increases the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH).


Symptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.

Composition and Active Ingredients

Each Tablet Contains
Diethyl stilbesterol BP                        5mg
Excipients                                            q.s.


Stilbestrol Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Postpartum lactation suppression
  • Atrophic vaginitis
  • Gonorrheal vaginitis
  • Menopausal symptoms

The following is a list of possible side-effects that may occur from all constituting ingredients of Stilbestrol Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

  • Breast tenderness
  • Enlarged breasts
  • Fluid retention in the legs, feet, arms or hands
  • Weight gain
  • Decreased breast milk production
  • Loss of appetite
  • Stilbestrol Tabletmay also cause side-effects not listed here.

If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.

Interactions with Stilbestrol Tablet

If you use other drugs or over the counter products at the same time, the effects of Stilbestrol Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Stilbestrol Tablet may interact with the following drugs and products:

  • Bexarotene
  • Dantrium
  • Dantrolene
  • Hemin
  • Lenalidomide
  • Tranexamic acid

Before using Stilbestrol Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

  • Breast feeding
  • Planning to have baby
When not to use Stilbestrol Tablet

Hypersensitivity to Stilbestrol Tablet is a contraindication. In addition, Stilbestrol Tablet should not be used if you have the following conditions:

  • Allergic
  • Pregnancy
Patient Information

Is Stilbestrol Tablet safe to use when pregnant?


Is Stilbestrol Tablet safe while breastfeeding?

Please discuss the risks and benefits with your doctor.

Can Stilbestrol Tablet be used for postpartum lactation suppression and atrophic vaginitis?

Yes, postpartum lactation suppression and atrophic vaginitis are among the most common reported uses for Stilbestrol Tablet. Please do not use Stilbestrol Tablet for postpartum lactation suppression and atrophic vaginitis without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Stilbestrol Tablet.

How long do I need to use Stilbestrol Tablet before I see improvement of my conditions? website users have reported 2 days and 1 week as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Stilbestrol Tablet. Click here and view survey results to find out what other patients report as time for effectiveness for Stilbestrol Tablet.

Should I use Stilbestrol Tablet empty stomach, before food or after food? website users have most commonly reported using Stilbestrol Tablet after food. However, this may not be reflective of how you should use this medicine. Please follow your doctor’s advice on how you should use this medicine. Click here and view survey results to find out what other patients report as timing of using Stilbestrol Tablet.

Is it safe to drive or operate heavy machinery when using this product?

If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Stilbestrol Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Stilbestrol Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.

Is this medicine or product addictive or habit forming?

Most medicines don’t come with a potential for addiction or abuse. Usually, government’s categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body’s dependence to medicines without the advice of a doctor.

Can i stop using this product immediately or do I have to slowly ween off the use?

Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Stilbestrol Tablet
Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Stilbestrol Tablet
  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Stilbestrol Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
Storage of Stilbestrol Tablet
  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Stilbestrol Tablet.

Expired Stilbestrol Tablet

  • Taking a single dose of expired Stilbestrol Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
Packages and Strengths

Stilbestrol Tablet is available in the following packages and strengths

Stilbestrol Tablet – Packages: 5MG

Manufactured in India by:
Mumbai, India
Unit No. 214.Old Bake House,
Maharashtra chambers of  Commerce Lane,
Fort, Mumbai – 400001
at:Gujarat, INDIA.
Customer Service and Product Inquiries:
1-800-TRY-FIRST (1-800-222-434 & 1-800-222-825)
Monday through Saturday 9:00 a.m. to 7:00 p.m. EST