D-Penicillamine Capsules USP 250mg Manufacturers, Suppliers in India:

Taj Pharmaceuticals is of the prominent D-Penicillamine Capsules USP 250mg Manufacturers in India, bringing the best quality products. Our company Taj Pharma has rich experience in the niche manufacturing of D-Penicillamine Capsules.

Taj Pharmaceuticals is a reputed manufacturer and D-Penicillamine Capsules Supplier in India prefer Taj Pharma is best known for the topmost standards and consistent quality of its products.

D-Penicillamine Capsules are used in the treatment of Wilson’s complaint, a heritable disease that prevents the body from removing spare Copper, causing Copper to make up in the liver, brain, eyes, and other organs. also, D-Penicillamine Capsules are used in the treatment of rheumatoid arthritis which is an autoimmune and seditious disease. It can also be used in Cystinuria, a condition in which monuments of amino acid( cysteine) are formed in the order, ureter, and urinary bladder. likewise, for the proper immersion of D-Penicillamine, it’s judicious to take D-Penicillamine Capsules one hour before or two hours after the meal.

Taj Pharma is a well-known D-Penicillamine Capsules Manufacturer in India that assures high- quality and high standards. Strict quality control ensures that every batch of medicine brings a harmonious standard.

D-Penicillamine Capsules manufactured at Taj Pharma follow ICH; i.e., the product is manufactured to comply with good quality standards, considered the Best in the world. Further, Taj Pharma uses D-Penicillamine Capsules graded as the best active ingredient to manufacture its Injections to comply with international standards of European products.

Product Name:D-Penicillamine Capsules USP
Brand Name:Penici-D
Strength:250mg
Dosage Form:Capsules
Route of Administration:Via Oral Route
Packing:10s, 30s, 100s, 500s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antirheumatic
Indication: D-Penicillamine is used to treat rheumatoid arthritis, Wilson’s disease (a condition in which high levels of copper in the body cause damage to the liver, brain, and other organs), and a certain disorder which causes kidney stones (cystinuria).
Storage:Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].

D-Penicillamine Capsules PAN India Manufacturers, Suppliers

Taj Pharmaceuticals Limited is one of India’s most estimable and extensively honored manufacturers of heavy metal antagonists D-Penicillamine Capsules. We exceed at maintaining the loftiest industrial norms as we work to come one of the top suppliers and exporters in the pharmaceutical sector for D-Penicillamine Capsules. We have a slice-edge manufacturing installation that’s furnished with all the necessary tools, equipment, and resources needed for the product of D-Penicillamine Capsules.

What are D-Penicillamine Capsules?

D-Penicillamine Capsules are used in the treatment of Wilson’s complaint, an inheritable complaint that prevents the body from removing spare Copper, causing Copper to make up in the liver, brain, eyes, and other organs. also, D-Penicillamine Capsules are used in the treatment of rheumatoid arthritis which is an autoimmune and inflammatory disease. It can also be used in Cystinuria, a condition in which demitasse of amino acid( cysteine) are formed in the order, ureter, and urinary bladder. likewise, for the proper absorption of D-Penicillamine, it’s judicious to take D-Penicillamine Capsules one hour before or two hours after the food. Its effectiveness appears to be analogous to that of other disease-modifying anti-rheumatic drugs( DMARDs) but with a significantly advanced poison.

Why Taj Pharmaceuticals Limited?

Taj Pharmaceuticals Limited is one of India’s dominant manufacturers of D-Penicillamine Capsules, and it’s a heavy metal antagonist and it’s used in the treatment of Wilson’s disease. D-Penicillamine Capsules USP 250mg is a competitive asset of Chelating agents. The primary clinically important pharmacologic exertion of D-Penicillamine is the removal of excess copper in patients with Wilson’s disease. The In-Vitro studies indicate that one molecule of copper binds with the two molecules of D-penicillamine. The mechanism of D-penicillamine in Wilson’s disease is to remove extra copper in the body by forming the chemical bonds and leave the body through the urine

How does D-Penicillamine Capsules Work?

D-Penicillamine is a pharmaceutical derivative of penicillin and works by chelating certain metals in the body, such as copper and lead. It has several mechanisms of action:

Chelation of Metals:

  • D-Penicillamine forms a stable complex (chelate) with certain metals, particularly copper. This process makes it easier for the body to excrete these metals through urine, reducing their levels in the body.
  • In the case of Wilson’s disease, where there is an accumulation of copper, D-Penicillamine binds to excess copper and facilitates its removal from the body.

Immunomodulatory Effects:

  • D-Penicillamine has immunomodulatory properties, particularly in the treatment of autoimmune diseases like rheumatoid arthritis.
  • It may suppress certain aspects of the immune response that contribute to inflammation and joint damage in conditions like rheumatoid arthritis.

Collagen Degradation Inhibition:

  • In rheumatoid arthritis, D-Penicillamine might also interfere with the formation of collagen, a major component of connective tissues. This action may contribute to its anti-inflammatory effects.

Cystine Reduction:

  • D-Penicillamine is also used in the treatment of cystinuria, a condition where high levels of cystine in urine can form stones in the kidneys or bladder. It works by breaking down cystine into smaller, more soluble molecules, reducing the risk of stone formation.

Benefits and Side effects of -Penicillamine Capsules?

D-Penicillamine, a medication used to treat conditions like Wilson’s disease, rheumatoid arthritis, and cystinuria, has both beneficial effects and potential side effects. Here are the main benefits and side effects associated with D-Penicillamine capsules:

Benefits:

  • Treatment of Wilson’s Disease: D-Penicillamine effectively reduces copper levels in individuals with Wilson’s disease by chelating excess copper and aiding its elimination from the body through urine. This helps prevent copper accumulation in organs like the liver and brain.
  • Rheumatoid Arthritis Management: It is used to manage symptoms of rheumatoid arthritis by suppressing the immune response and reducing inflammation in the joints, potentially slowing down joint damage and alleviating pain and swelling.
  • Cystinuria Treatment: D-Penicillamine assists in treating cystinuria by helping to break down cystine, a component of stones that form in the kidneys or bladder, into more soluble compounds, thereby reducing the risk of stone formation.

 Side Effects:

  • Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, and loss of appetite. These symptoms can sometimes be severe and may require discontinuation of the medication.
  • Skin Reactions: D-Penicillamine might cause various skin issues, such as rashes, itching, and skin ulcers.
  • Kidney Issues: It can affect kidney function and may lead to kidney stones or protein in the urine (proteinuria). Regular monitoring of kidney function is crucial while taking D-Penicillamine.
  • Blood Disorders: Some individuals might experience blood-related side effects, including decreased white blood cell count (increased susceptibility to infections), decreased platelet count (increased risk of bleeding), or anemia.
  • Neurological Effects: Rarely, neurological side effects like myasthenia gravis (a neuromuscular disease), seizures, or neuropathies (nerve damage) may occur.
  • Other Side Effects: Hair loss, changes in taste, and oral ulcers are among the less common side effects associated with D-Penicillamine.

Precautions:

  • D-Penicillamine should be taken under strict medical supervision.
  • Regular monitoring of blood tests, kidney function, and other parameters is essential while taking D-Penicillamine.
  • Inform your healthcare provider about any allergies, medications, or medical conditions before starting D-Penicillamine.
  • Pregnancy and breastfeeding women should use this medication with caution, as it may pose risks to the fetus or infant.

Frequently asked questions (FAQs) about D-Penicillamine capsules:

  1. What is D-Penicillamine used for?

D-Penicillamine is primarily used to treat conditions like Wilson’s disease (to reduce copper levels), rheumatoid arthritis (to manage inflammation and symptoms), and cystinuria (to prevent kidney stone formation).

  1. How does D-Penicillamine work?

D-Penicillamine works by chelating or binding to certain metals like copper, forming stable compounds that are easily excreted from the body through urine. It also has immunomodulatory effects that help in managing autoimmune conditions like rheumatoid arthritis.

  1. How should I take D-Penicillamine?

It’s important to follow your doctor’s prescription and take D-Penicillamine exactly as directed. Typically, it’s taken on an empty stomach, at least one hour before or two hours after meals, to improve absorption.

  1. What are the common side effects of D-Penicillamine?

Common side effects include gastrointestinal issues like nausea, vomiting, diarrhea, loss of appetite, skin rashes, kidney problems, blood disorders, and neurological symptoms.

  1. Are there any foods or medications I should avoid while taking D-Penicillamine?

Avoid taking vitamins or supplements containing minerals like zinc, iron, or calcium at the same time as D-Penicillamine, as they might interfere with its absorption. Alcohol consumption should be limited or avoided due to potential liver complications.

  1. How long does it take for D-Penicillamine to start working?

The time it takes for D-Penicillamine to show effects can vary based on the condition being treated. It may take weeks to months to see significant improvements in symptoms.

  1. Can D-Penicillamine be taken during pregnancy or breastfeeding?

Pregnant or breastfeeding individuals should consult their doctor before taking D-Penicillamine, as it may pose risks to the fetus or infant. The benefits and risks should be carefully evaluated in such cases.

  1. Is it safe to abruptly stop taking D-Penicillamine?

No, it’s important not to stop taking D-Penicillamine suddenly without consulting your doctor. Stopping abruptly might worsen the condition being treated or lead to withdrawal effects.

  1. Can D-Penicillamine interact with other medications?

Yes, D-Penicillamine can interact with various medications. It’s crucial to inform your doctor about all medications, including over the counter drugs, supplements, and herbal products, before starting D-Penicillamine.

  1. How often do I need to have medical checkups while on D-Penicillamine?

Regular medical checkups and monitoring are essential while taking D-Penicillamine. Your doctor will likely schedule frequent blood tests, kidney function tests, and other assessments to monitor its effects and any potential side effects.

We are exporting our D-Penicillamine Capsules product to Following Countries:

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, Iraq.

North and Central America: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Suriname,

South America: Brazil, Argentina, Bolivia, Chile, Colombia, Ecuador, French Guiana, Guyana, Paraguay, Peru, Uruguay, Venezuela

Caribbean Countries: Jamaica, Cuba, Dominican Republic, Haiti, Guadeloupe, Martinique, Puerto Rico, Saint-Barthelemy, Saint-Martin, St Lucia, Trinidad & Tobago,

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan, and Ukraine,

African Countries: Kenya, Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia, Mozambique, Malawi, Seychelles, Gambia, Somalia, Sierra Leone, Libya

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Countries: Turkey, Cyprus, Cayman Island, Papua New Guinea (PNG), All West Indies Country

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

D-Penicillamine Capsules 250mg Regulatory Documents:

  1. Certificate of Analysis (COA)
  2. Method of Analysis (MOA)
  3. Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  4. eCTD Dossiers / CTD Dossier / ACTD Dossiers
  5. Certificate of Pharmaceuticals Product (COPP)

Contact the most reliable manufacturer of D-Penicillamine Capsules, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) D-Penicillamine Capsules USP 250mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) D-Penicillamine Capsules USP 250mg
Each Hard gelatin capsule contains:
Penicillamine USP……………………250mg
Excipients…………………………………. q.s.
Approved colours are used in empty capsule shells.

THERAPEUTIC INDICATIONS:

Penicillamine is used to treat rheumatoid arthritis, Wilson's disease (a condition in which high levels of copper in the body cause damage to the liver, brain, and other organs), and a certain disorder which causes kidney stones (cystinuria).

CAUTION & WARNING:

CAUTION:
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
WARNING: To be sold by retail on the prescription of a registered medical practitioner only.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].
Dispense in tight and light resistant container.
Dosage: As directed by the physician.