Clomipramine HCl Tablets 75mg Technical Specification:

Product Name:            Clomipramine HCl Tablets 75mg
Brand Name:CLOMIPRAMINE
Strength:25gm, 50mg, 75mg
Dosage Form:Tablet (Film-coated)
Route of Administration:Via oral Route
Packing:100s, 500s.1000s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antidepressants, Central Nervous System
Indication: Clomipramine is used to treat obsessive compulsive disorder (OCD). OCD is a nervous condition wherein a person has recurring thoughts or ideas or does repetitive things because they are anxious. Clomipramine is a tricyclic antidepressant (TCA).
Storage:Do not store above 30°C.Oral solution: Store in the original container to protect from light.

GENERIC NAME OF THE MEDICINAL PRODUCT: 

  • Clomipramine HCl Tablets 75mg (Clomipramine)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Clomipramine HCl Tablets USP 75mg
    Each film coated Tablet Contains:
    Clomipramine Hydrochloride……………75mg
    Excipients………………………………………q.s.
    Colour: D&C Red 27 Lake

 THERAPEUTIC INDICATIONS:

Clomipramine Tablets are indicated for the treatment of:
the symptoms of depressive illness especially where sedation is required
obsessional and phobic states
adjunctive treatment of cataplexy associated with narcolepsy.

CAUTION & WARNING:

CAUTION: Read enclosed leaflet before use.
Keep medicine out of reach of children.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Protect form moisture at a temperature not exceeding 30˚C. Do not freeze.
Keep the container tightly closed in order to protect from moisture.
Dosage: As directed by the Physician.

Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals: Your Trusted Choice for Clomipramine HCl Tablets
When it comes to your mental health and well-being, Taj Pharmaceuticals stands as your unwavering partner. Our commitment to excellence extends to every aspect of our pharmaceutical offerings, including Clomipramine HCl Tablets. Clomipramine is a vital medication used to treat a range of mental health disorders, particularly obsessive-compulsive disorder (OCD) and depression. At Taj Pharmaceuticals, we prioritize your mental wellness by ensuring the utmost quality and efficacy of our Clomipramine HCl Tablets.
Expertise and Innovation: With a legacy of pharmaceutical expertise and a dedication to innovation, Taj Pharmaceuticals has developed Clomipramine HCl Tablets that adhere to the highest industry standards. We continuously strive to provide cutting-edge solutions for mental health challenges.
Effective Treatment: Clomipramine is a proven treatment for OCD and depression, helping individuals regain control over their lives. Our tablets are formulated to deliver the precise dosage needed for symptom relief and improved quality of life.
Quality Assurance: Taj Pharmaceuticals maintains rigorous quality control measures at every stage of production to ensure that our Clomipramine HCl Tablets consistently meet safety and efficacy standards. Your well-being is our top priority.
Patient-Centered Care: We understand the importance of individualized care in mental health treatment. Taj Pharmaceuticals offers not just a product but a comprehensive approach to mental health, supporting your journey toward a happier, healthier life.
Choose Taj Pharmaceuticals for Clomipramine HCl Tablets and experience the difference that commitment to excellence and patient-focused care can make in your mental health treatment. Trust us to provide the quality and support you deserve.

What is Clomipramine HCl Tablets and its uses:

Clomipramine HCl Tablets are a medication containing clomipramine hydrochloride, a tricyclic antidepressant (TCA) renowned for its versatile therapeutic applications. These tablets serve as a valuable tool in addressing a spectrum of mental health conditions.

Obsessive-Compulsive Disorder (OCD): One prominent use of Clomipramine HCl Tablets is in the treatment of obsessive-compulsive disorder (OCD). This condition is marked by distressing, intrusive thoughts and repetitive behaviors. Clomipramine aids in reducing the frequency and intensity of these obsessions and compulsions, offering individuals with OCD relief and improved daily functioning.

Depression: Clomipramine is a trusted choice for managing major depressive disorder (MDD), especially when other antidepressant medications have proven ineffective. It alleviates the symptoms associated with depression, including persistent sadness, loss of interest, appetite changes, and sleep disturbances.

Panic Disorder: Clomipramine may also be prescribed to address panic disorder, characterized by recurrent panic attacks and severe anxiety symptoms. This medication assists in lessening the frequency and severity of panic attacks, providing individuals with greater control over their anxiety.

Other Anxiety Disorders: Beyond OCD and panic disorder, Clomipramine HCl Tablets find utility in managing various anxiety disorders, such as generalized anxiety disorder (GAD) and social anxiety disorder. These tablets are considered when other treatments have not yielded satisfactory results.

Chronic Pain Syndromes: In certain situations, clomipramine is employed off-label to alleviate chronic pain syndromes like neuropathic pain and fibromyalgia, owing to its analgesic properties.

It’s vital to underscore that the use of Clomipramine HCl Tablets necessitates the close supervision and guidance of a healthcare provider. The specific dosage and treatment duration are determined based on the individual’s condition and response to the medication. Patients should not make abrupt changes to their medication without consulting their healthcare provider to avoid withdrawal symptoms or symptom recurrence.

How does Clomipramine HCl Tablets Work?

Clomipramine HCl Tablets operate by modifying the balance of key neurotransmitters in the brain, primarily serotonin and norepinephrine. As a tricyclic antidepressant (TCA), clomipramine employs a multi-faceted mechanism of action to deliver therapeutic benefits.

  • Enhancing Neurotransmitter Levels: Clomipramine exerts its influence by inhibiting the reuptake of serotonin and norepinephrine into nerve cells. This inhibition leads to an increase in the availability of these neurotransmitters in the synaptic cleft, facilitating more efficient nerve cell communication.
  • Mood and Emotion Regulation: The augmented levels of serotonin and norepinephrine in the brain play pivotal roles in the regulation of mood, emotions, and anxiety. Clomipramine’s action aids in stabilizing mood and mitigating symptoms of depression and anxiety disorders, contributing to a reduction in feelings of sadness, anxiety, and restlessness.
  • Balancing Brain Chemistry: In conditions like depression and anxiety disorders, disruptions in brain chemistry are common. Clomipramine assists in rectifying this imbalance, fostering a more stable and harmonious brain chemistry. This rebalancing results in an amelioration of associated symptoms.
  • Pain Relief: Beyond its antidepressant effects, clomipramine also possesses analgesic properties. It can alleviate the perception of pain, particularly in individuals grappling with chronic pain syndromes like neuropathic pain and fibromyalgia. Although the precise mechanisms of its analgesic action are not entirely elucidated, it is thought to involve the modulation of pain signals in the central nervous system.

It is vital to underscore that the therapeutic effects of Clomipramine HCl Tablets may necessitate several weeks of consistent use before becoming fully evident. These tablets should be taken in accordance with the healthcare provider’s prescription, with any dosage adjustments or discontinuation being made solely under their guidance. Additionally, individuals utilizing clomipramine should be closely monitored for potential side effects and adverse reactions to ensure safe and effective treatment.

Benefits of Clomipramine HCl Tablets:

Clomipramine HCl Tablets offer several valuable benefits in the realm of mental health and pain management. First and foremost, they are highly effective in treating major depressive disorder (MDD), providing relief from symptoms such as persistent sadness and changes in appetite and sleep patterns. Additionally, these tablets are a mainstay in the management of obsessive-compulsive disorder (OCD), significantly reducing the frequency and intensity of distressing obsessions and compulsions.

Furthermore, Clomipramine HCl Tablets can be a lifeline for individuals battling panic disorder, offering respite from the distressing grip of recurring panic attacks and anxiety symptoms. They also extend their therapeutic reach to encompass other anxiety disorders, including generalized anxiety disorder (GAD) and social anxiety disorder, when other treatments have fallen short.

Beyond mental health, Clomipramine’s analgesic properties make it a valuable option for those grappling with chronic pain syndromes like neuropathic pain and fibromyalgia. This multifaceted medication thus stands as a versatile solution for various conditions, enhancing the overall quality of life for those it serves.

Side Effects of Clomipramine HCl Tablets:

Clomipramine HCl Tablets, like many medications, may entail certain side effects. Common side effects include dry mouth, constipation, blurred vision, dizziness, drowsiness, and weight gain. While these effects are generally manageable and tend to diminish with time, they should be closely monitored.

One notable side effect is orthostatic hypotension, characterized by a drop in blood pressure upon standing, which can lead to dizziness or fainting. Additionally, Clomipramine can have cardiovascular effects, including an increased heart rate or irregular heart rhythms, necessitating careful observation for cardiac-related symptoms.

The medication’s anticholinergic properties can manifest as dry mouth, constipation, and difficulties with urination. Sexual side effects, such as decreased libido and sexual dysfunction, may also occur. Moreover, although rare, neuropsychiatric effects like agitation, confusion, and hallucinations have been reported.

Patients should be aware of the possibility of serotonin syndrome, a rare but serious condition associated with symptoms like agitation, rapid heartbeat, and hallucinations, and seek immediate medical attention if such symptoms arise. It’s paramount to use Clomipramine HCl Tablets under the guidance of a healthcare provider who can monitor for side effects and make necessary adjustments to optimize the medication’s benefits while minimizing risks.

Frequently Asked Questions About Clomipramine HCl Tablets:

Certainly, here are some frequently asked questions (FAQs) about Clomipramine HCl Tablets:

  1. What are Clomipramine HCl Tablets used for?

Clomipramine HCl Tablets are used to treat a range of mental health conditions, including major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder, other anxiety disorders, and certain chronic pain syndromes.

  1. How does Clomipramine work?

Clomipramine works by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain. These neurotransmitters play a crucial role in regulating mood, emotions, and anxiety.

  1. How long does it take for Clomipramine HCl Tablets to start working?

The therapeutic effects of Clomipramine may take several weeks to become fully noticeable. Patients are advised to continue taking the medication as prescribed, even if they do not immediately experience symptom relief.

  1. Are there any common side effects of Clomipramine HCl Tablets?

Common side effects may include dry mouth, constipation, blurred vision, dizziness, drowsiness, and weight gain. These side effects are typically mild and tend to improve over time.

  1. Can Clomipramine HCl Tablets be used during pregnancy or breastfeeding?

Use during pregnancy and breastfeeding should be carefully discussed with a healthcare provider, as there are potential risks and benefits that need to be considered.

  1. Can Clomipramine be taken with other medications?

Clomipramine may interact with other medications, so it’s crucial to inform your healthcare provider about all the medications, including over-the-counter and herbal supplements, that you are taking to avoid potential interactions.

  1. Is it safe to drink alcohol while taking Clomipramine?

Alcohol should be avoided or limited while taking Clomipramine, as it can intensify the sedative effects and increase the risk of side effects.

  1. Can Clomipramine be abruptly stopped?

No, Clomipramine should not be abruptly stopped without consulting a healthcare provider. Gradual dose reduction may be necessary to avoid withdrawal symptoms.

  1. Is it safe to drive or operate machinery while taking Clomipramine HCl Tablets?

Clomipramine may cause dizziness and drowsiness. Patients should exercise caution when driving or operating machinery until they know how the medication affects them.

  1. How long is Clomipramine typically prescribed for?

The duration of Clomipramine treatment varies depending on the individual’s condition and response to the medication. It may be prescribed for several months or longer for some conditions, while for others, it may be used for shorter periods.

Patients are encouraged to consult their healthcare provider for personalized information and guidance regarding the use of Clomipramine HCl Tablets, as well as any specific questions or concerns they may have.

As Clomipramine HCl Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Clomipramine HCl Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Clomipramine HCl Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Clomipramine HCl Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Clomipramine HCl Tablets 25gm (Clomipramine)
B) Clomipramine HCl Tablets 50mg (Clomipramine)
C) Clomipramine HCl Tablets 75mg (Clomipramine)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Clomipramine HCl Tablets USP 25gm
Each film coated Tablet Contains:
Clomipramine Hydrochloride……………...25mg
Excipients………………………………………q.s.
Colour: Ponceau 4R

B) Clomipramine HCl Tablets USP 50mg
Each film coated Tablet Contains:
Clomipramine Hydrochloride……………...50mg
Excipients………………………………………q.s.
Colour: Iron Oxide Red

C) Clomipramine HCl Tablets USP 75mg
Each film coated Tablet Contains:
Clomipramine Hydrochloride……………75mg
Excipients………………………………………q.s.
Colour: D&C Red 27 Lake


THERAPEUTIC INDICATIONS:

Clomipramine Tablets are indicated for the treatment of:
– the symptoms of depressive illness especially where sedation is required
– obsessional and phobic states
– adjunctive treatment of cataplexy associated with narcolepsy.

CAUTION & WARNING:

CAUTION:
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Protect form moisture at a temperature not exceeding 30˚C. Do not freeze. Keep the container tightly closed in order to protect from moisture.
Dosage: As directed by the Physician.
Attach dispensing label as per end country.