Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg Technical Specification:
Product Name: | Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg |
Brand Name: | Generic |
Strength: | (2.5mg+6.25mg), (5mg+6.25mg), (5mg+12.5mg), (10mg+6.25mg) |
Dosage Form: | Tablets (film-coated) |
Route of Administration: | Via Oral Route |
Packing: | 10s, 30s, 100s, 500s |
Pack Insert/Leaflet: | PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics) |
Regulatory Documents: | COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier |
Therapeutic use: | Antihypertensive |
Indication: | Bisoprolol Fumarate and Hydrochlorothiazide is indicated for the treatment of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1 selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide). |
Storage: | Store at 20°C to 25°C (68°F to 77°F). Store in dry place protected from light and moisture. |
GENERIC NAME OF THE MEDICINAL PRODUCT:
- Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
QUALITATIVE AND QUANTITATIVE COMPOSITION:
- Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….5mg
Hydrochlorothiazide USP………………….12.5mg
Excipients……………………..………………… q.s
Colour: Sunset yellow
THERAPEUTIC INDICATIONS:
Bisoprolol Fumarate and Hydrochlorothiazide is indicated for the treatment of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1 selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide).
CAUTION & WARNING:
CAUTION: Read enclosed leaflet before use.
Keep medicine out of reach of children.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.
DISPENSE IN A TIGHT CONTAINER.
TAKE THIS PREPARATION IN THE MORNING WITH OR WITHOUT FOOD.
IT IS DANGEROUS TO TAKE THIS PREPARATION EXCEPT UNDER MEDICAL SUPERVISION.
Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.
STORAGE & DOSAGE:
Storage: Store at 20°C to 25°C (68°F to 77°F)
Store in dry place protected from light and moisture.
Dosage: As directed by the Physician
Attach dispensing label as per end country.
Why Taj Pharmaceuticals?
Unlock a world of reliability and trust with Taj Pharmaceuticals’ Bisoprolol Fumarate and Hydrochlorothiazide Tablets. With a legacy of pharmaceutical excellence spanning decades, we pride ourselves on being your premier choice for this vital medication. At Taj Pharmaceuticals, our mission is to ensure your well-being. We understand the importance of medications like Bisoprolol Fumarate and Hydrochlorothiazide in managing hypertension and cardiac conditions. That’s why we adhere to the highest quality standards in manufacturing, ensuring that each tablet you receive is consistent in efficacy and safety. Our commitment to affordability sets us apart. We believe that essential medications should be accessible to everyone. Taj Pharmaceuticals strives to keep the cost of Bisoprolol Fumarate and Hydrochlorothiazide Tablets within reach, without compromising on quality. Your health should never be compromised by financial constraints, and we’re here to make sure of that. When you choose Taj Pharmaceuticals, you’re not just getting medication; you’re getting peace of mind. Our dedication to patient care means you can trust in the integrity of our products. Your health is our priority, and we’re honored to be part of your journey toward a healthier, happier life. Experience the Taj Pharmaceuticals difference today. Join countless others who have made us their go-to source for Bisoprolol Fumarate and Hydrochlorothiazide Tablets. Together, we’ll pave the way to a healthier tomorrow, one reliable tablet at a time.
What is Bisoprolol Fumarate and Hydrochlorothiazide Tablets and its uses:
Bisoprolol Fumarate and Hydrochlorothiazide Tablets are a combined medication designed to address cardiovascular issues, primarily focusing on the treatment of hypertension, commonly known as high blood pressure. This medication consists of two key components, each serving a distinct purpose in managing cardiovascular health. Bisoprolol Fumarate, a beta-blocker, works by inhibiting the effects of natural substances like adrenaline on the heart and blood vessels. By doing so, it lowers blood pressure, alleviates the heart’s workload, and helps regulate heart rhythm. This versatile component is instrumental in managing hypertension, angina (chest pain), and heart failure. On the other hand, Hydrochlorothiazide, a diuretic or “water pill,” increases urine production in the body, aiding in the removal of excess salt and water. This reduction in fluid volume within the bloodstream contributes to the lowering of blood pressure. Hydrochlorothiazide is frequently used alongside other antihypertensive medications to achieve more effective blood pressure control.
Bisoprolol Fumarate and Hydrochlorothiazide Tablets are commonly prescribed for several purposes:
- Hypertension (High Blood Pressure): This medication is a cornerstone in the treatment of high blood pressure, reducing the risk of heart-related complications such as heart attacks and strokes.
- Hypertension Management: Combining both components, this medication can offer superior blood pressure control for individuals struggling with hypertension.
- Heart Failure: Bisoprolol, when used in conjunction with other heart failure medications, can alleviate symptoms and enhance cardiac function in individuals with heart failure.
- Angina (Chest Pain): Bisoprolol helps relieve angina symptoms by reducing the heart’s workload and enhancing blood flow to the heart muscle.
It is vital to underline that Bisoprolol Fumarate and Hydrochlorothiazide Tablets should only be used under the guidance and prescription of a healthcare professional. Dosage and administration instructions may vary based on individual medical histories and conditions. Always consult with a healthcare provider to receive personalized guidance and discuss potential side effects or interactions with other medications.
How does Bisoprolol Fumarate and Hydrochlorothiazide Tablets work?
Bisoprolol Fumarate and Hydrochlorothiazide Tablets employ a dual-action approach to manage cardiovascular conditions, primarily hypertension (high blood pressure). The medication combines two key components, bisoprolol fumarate and hydrochlorothiazide, each with distinct functions. Bisoprolol Fumarate (Beta-Blocker) acts by targeting beta receptors in the heart and blood vessels. By binding to these receptors, it mitigates the effects of adrenaline, which would otherwise stimulate the heart and elevate blood pressure. This results in a slower, less forceful heartbeat, reducing blood pressure, lightening the heart’s workload, and stabilizing irregular heart rhythms. Additionally, bisoprolol induces relaxation in blood vessels, contributing further to blood pressure reduction. Hydrochlorothiazide (Diuretic/Water Pill) operates as a diuretic, effectively increasing urine production. This leads to the expulsion of excess salt and water from the bloodstream. As blood volume decreases due to increased urination, overall blood pressure diminishes. This is due to the reduced fluid volume exerting pressure on the walls of blood vessels.
The Synergistic Effect:
When combined, Bisoprolol Fumarate and Hydrochlorothiazide work harmoniously to manage hypertension comprehensively. Bisoprolol regulates heart rate and function, while hydrochlorothiazide reduces blood volume through enhanced urine production. This combined action effectively lowers blood pressure by reducing both the force of the heart’s contractions and the overall volume of blood in circulation. This dual approach often proves more effective in blood pressure control than using a single medication in isolation. It is imperative to recognize that the exact dosage and mechanism of action may vary based on an individual’s specific medical condition and requirements. Consequently, the use of Bisoprolol Fumarate and Hydrochlorothiazide Tablets should be under the supervision and prescription of a healthcare provider. This ensures a safe and effective treatment for hypertension or other cardiovascular conditions.
Benefits of Bisoprolol Fumarate and Hydrochlorothiazide Tablets:
Bisoprolol Fumarate and Hydrochlorothiazide Tablets offer several notable advantages in the management of cardiovascular conditions, primarily high blood pressure (hypertension). Their primary benefit lies in their effectiveness at controlling blood pressure, reducing the risk of severe cardiovascular complications like heart attacks, strokes, and kidney problems. A key feature of this medication is its dual-action approach, combining bisoprolol, a beta-blocker, and hydrochlorothiazide, a diuretic. This synergy often provides more comprehensive blood pressure control compared to single-agent therapies, making it a valuable option for individuals with complex hypertension.
For those dealing with angina or heart failure, these tablets offer symptom relief by reducing the heart’s workload and enhancing blood flow. Additionally, bisoprolol has the potential to stabilize irregular heart rhythms (arrhythmias), further enhancing its therapeutic benefits.
Common Side Effects Bisoprolol Fumarate and Hydrochlorothiazide Tablets:
While Bisoprolol Fumarate and Hydrochlorothiazide Tablets offer significant benefits, they may also be associated with several side effects. These commonly include fatigue, weakness, dizziness, and headaches, which are often transient and tend to subside over time. Increased urination is a typical effect of hydrochlorothiazide due to its diuretic action. Electrolyte imbalances, particularly low potassium or sodium levels, can occur and necessitate monitoring by healthcare providers.
Less Common Side Effects:
Less frequently, users may experience nausea, vomiting, changes in blood sugar levels (especially in individuals with diabetes), sexual dysfunction, skin reactions, and exacerbation of certain pre-existing conditions like asthma or COPD. While these side effects are less common, they should be discussed with a healthcare provider if they occur.
It’s important to recognize that not everyone will experience these side effects, and their severity can vary widely among individuals. A healthcare provider will carefully assess an individual’s medical history, monitor their response to the medication, and make necessary adjustments to ensure both efficacy and tolerance. In the event of concerning or severe side effects, prompt communication with a healthcare provider is crucial to explore potential treatment modifications or alternative options.
Frequently Asked Questions About Bisoprolol Fumarate and Hydrochlorothiazide Tablets:
Certainly, here are some frequently asked questions about Bisoprolol Fumarate and Hydrochlorothiazide Tablets:
- What are Bisoprolol Fumarate and Hydrochlorothiazide Tablets used for?
These tablets are primarily used to treat high blood pressure (hypertension) and may also be used for conditions like angina and heart failure.
- How do Bisoprolol Fumarate and Hydrochlorothiazide Tablets work?
These tablets work by combining two medications: bisoprolol, a betablocker that slows the heart rate and reduces blood pressure, and hydrochlorothiazide, a diuretic that increases urine production, thereby reducing blood volume.
- Are there any potential side effects?
Yes, common side effects can include fatigue, dizziness, headache, increased urination, and electrolyte imbalances. Less common side effects may include nausea, vomiting, sexual dysfunction, skin reactions, and changes in blood sugar levels.
- Can I take other medications with Bisoprolol Fumarate and Hydrochlorothiazide Tablets?
It’s important to discuss all medications and supplements you are taking with your healthcare provider before starting this medication to ensure there are no potential interactions.
- How should I take these tablets?
Follow your healthcare provider’s instructions carefully. Typically, these tablets are taken orally with or without food. It’s essential to take them at the same time each day for optimal effectiveness.
- Can I drink alcohol while taking this medication?
It’s generally advisable to limit alcohol consumption while taking these tablets, as alcohol can interact with the medication and exacerbate certain side effects, such as dizziness or drowsiness.
- What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
- How long does it take for Bisoprolol Fumarate and Hydrochlorothiazide Tablets to start working?
You may start to see a reduction in blood pressure within a few hours to days of starting the medication. However, it may take several weeks to achieve the full therapeutic effect.
- Can I stop taking these tablets if my blood pressure improves?
It’s essential to continue taking these tablets as prescribed by your healthcare provider, even if your blood pressure improves. Suddenly stopping medication can lead to a rebound increase in blood pressure.
- Are there any lifestyle changes I should make while taking this medication?
Your healthcare provider may recommend lifestyle changes such as dietary modifications, exercise, and stress management to complement the medication’s effectiveness in managing blood pressure.
- Can I take Bisoprolol Fumarate and Hydrochlorothiazide Tablets during pregnancy or while breastfeeding?
It’s crucial to consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as they can provide guidance on the safety and potential risks associated with this medication during these periods.
Always consult with your healthcare provider for personalized information and guidance regarding Bisoprolol Fumarate and Hydrochlorothiazide Tablets, as individual medical circumstances may vary.
As Bisoprolol Fumarate and Hydrochlorothiazide Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Bisoprolol Fumarate and Hydrochlorothiazide Tablets product in the Following Countries-
Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine
GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.
African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia
Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam
Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius
Bisoprolol Fumarate and Hydrochlorothiazide Tablets Regulatory Documents:
- Certificate of Analysis (COA)
- Method of Analysis (MOA)
- Stability Data (Accelerated stability / Long-term stability / Zone 4b)
- CTD Dossier / ACTD Dossiers / eCTD Dossiers
- Certificate of Pharmaceuticals Product (COPP)
- Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Bisoprolol Fumarate and Hydrochlorothiazide Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.
To Place Orders:
Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
GENERIC NAME OF THE MEDICINAL PRODUCT:
1. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 2.5mg+6.25mg
2. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+6.25mg
3. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
4. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 10mg+6.25mg
2. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+6.25mg
3. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
4. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 10mg+6.25mg
QUALITATIVE AND QUANTITATIVE COMPOSITION:
1. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 2.5mg+6.25mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….2.5mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Ferric oxide red
2. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+6.25mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….5mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Ferric oxide yellow
3. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….5mg
Hydrochlorothiazide USP………………….12.5mg
Excipients……………………..………………… q.s
Colour: Sunset yellow
4. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 10mg+6.25mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….10mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Sunset yellow lake
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….2.5mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Ferric oxide red
2. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+6.25mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….5mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Ferric oxide yellow
3. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 5mg+12.5mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….5mg
Hydrochlorothiazide USP………………….12.5mg
Excipients……………………..………………… q.s
Colour: Sunset yellow
4. Bisoprolol Fumarate and Hydrochlorothiazide Tablets USP 10mg+6.25mg
Each film-coated tablet contains:
Bisoprolol Fumarate USP………………….10mg
Hydrochlorothiazide USP………………….6.25mg
Excipients……………………..………………… q.s
Colour: Sunset yellow lake
THERAPEUTIC INDICATIONS:
Bisoprolol Fumarate and Hydrochlorothiazide is indicated for the treatment of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1 selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide).
CAUTION & WARNING:
CAUTION: Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.
DISPENSE IN A TIGHT CONTAINER.
TAKE THIS PREPARATION IN THE MORNING WITH OR WITHOUT FOOD.
IT IS DANGEROUS TO TAKE THIS PREPARATION EXCEPT UNDER MEDICAL SUPERVISION.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.
DISPENSE IN A TIGHT CONTAINER.
TAKE THIS PREPARATION IN THE MORNING WITH OR WITHOUT FOOD.
IT IS DANGEROUS TO TAKE THIS PREPARATION EXCEPT UNDER MEDICAL SUPERVISION.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
STORAGE & DOSAGE:
Storage: Store at 20°C to 25°C (68°F to 77°F)
Store in dry place protected from light and moisture.
Dosage: As directed by the Physician
Attach dispensing label as per end country.
Store in dry place protected from light and moisture.
Dosage: As directed by the Physician
Attach dispensing label as per end country.