Benzathine Penicillin Injection BP 1.2MIU  Technical Specification:

Product Name:Benzathine Penicillin Injection BP 1.2MIU
Brand Name:Generic
Strength:0.6MIU, 1.2MIU, 2.4MIU
Dosage Form:Dry Powder Injection (Sterile)
Packing:Vial + WFI in Tray
Route of Administration:For deep Intramuscular Injection only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Penicillin, β-lactam Antibiotic & Anti-bacterial
Indication: Benzathine benzylpenicillin, also known as benzathine penicillin G, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically, it is to treat strep throat, diphtheria, syphilis, and yaws.
Storage:Store below 25°C. Protect from light & moisture. Do not freeze.

GENERIC NAME OF MEDICINAL PRODUCT:

  •  Benzathine Penicillin Injection BP 1.2MIU

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Benzathine Penicillin Injection 1.2MIU
    Each vial contains:
    Benzathine Benzylpenicillin BP………. 1,200,000 units.
    Buffering Agent:
    Sodium Citrate BP
    Dispersing Agent:
    Sodium Carboxymethyl Cellulose USP
    Sterile Water for Injection BP……….10ml

 THERAPEUTIC INDICATION:

Benzathine benzylpenicillin, also known as benzathine penicillin G, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically, it is to treat strep throat, diphtheria, syphilis, and yaws. It is also used to prevent rheumatic fever. It is given by injection into a muscle.

DIRECTION OF USE:

Add 3-4 ml water for Injection before use.
The prepared solution should be used immediately.
Any unused reconstitution portion must be discarded.
For dosage, administration, and detailed direction of use, see package insert.

CAUTION & Warning:

CAUTION: Do not use the injection if the contents are not clear or contain visible particulate matter after reconstitution.
 “Penicillin Sensitivity Test Essential”
Not to be infused directly: Dilute the preparation with a compatible intravenous solution prior to administration.
For deep intramuscular injection only

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE

Warning: To be sold by the retail on the prescription of a Registered Medical Practitioner only.
Warning: If any particle is visible after dissolving the contents do not use & return for a replacement.

STORAGE & DOSAGE:

Storage: Store below 25°C.
Protect from light & moisture.
Do not freeze.

KEEP OUT OF REACH OF CHILDREN

Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Discover Taj Pharma’s Benzathine Penicillin Injection – your trusted choice for effective and reliable treatment of bacterial infections. With a legacy of pharmaceutical excellence and unwavering commitment to quality, Taj Pharma ensures safe and potent antibiotics that healthcare professionals and patients can rely on. Choose us for a healthier tomorrow. Taj Pharma is presented as a trusted provider of Benzathine Penicillin Injection, emphasizing the medication’s effectiveness in treating bacterial infections. It also underscores Taj Pharma’s commitment to quality and its role in promoting a healthier future. This meta description aims to capture the attention of healthcare professionals and patients searching for information about this antibiotic. Experience the reliability of Taj Pharma’s Benzathine Penicillin Injection – a time-tested solution for bacterial infections. Our commitment to cutting-edge research and uncompromising quality assurance ensures that each dose delivers effective results. With decades of pharmaceutical expertise, Taj Pharma remains dedicated to your well-being, providing healthcare professionals and patients with the peace of mind they deserve.

Benzathine Penicillin Injection by Taj Pharma is more than just an antibiotic; it’s a testament to our mission of advancing healthcare globally. Our rigorous manufacturing standards and a team of experts dedicated to your health make Taj Pharma the preferred choice for medical practitioners worldwide. Trust us for superior infection management and a healthier tomorrow. Taj Pharma’s dedication to research, quality assurance, and its long-standing commitment to improving global healthcare. It emphasizes that choosing Taj Pharma means choosing a reliable partner in infection management and a brighter future for healthcare.

What is Benzathine Penicillin Injection and its use?

Benzathine Penicillin Injection is a medication that contains a form of penicillin known as benzathine penicillin G. It is used to treat various bacterial infections. Here’s more information about Benzathine Penicillin Injection and its common uses:

  • Bacterial Infections: Benzathine Penicillin is primarily used to treat bacterial infections caused by susceptible organisms. These infections can affect various parts of the body, including the throat, skin, respiratory tract, and more.
  • Syphilis Treatment and Prevention: One of the most well-known uses of Benzathine Penicillin is in the treatment of syphilis, a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. It is often used for the early stages of syphilis, including primary and secondary syphilis. Additionally, it may be used to prevent syphilis transmission from an infected mother to her baby during pregnancy (congenital syphilis).
  • Rheumatic Fever and Rheumatic Heart Disease Prevention: Benzathine Penicillin is used as a prophylactic (preventive) treatment to prevent the recurrence of rheumatic fever and to prevent the development of rheumatic heart disease in individuals who have had an episode of acute rheumatic fever. This is especially important for patients with a history of rheumatic fever.
  • Streptococcal Infections: It can also be used to treat and prevent infections caused by Streptococcus bacteria, including strep throat and scarlet fever.
  • Other Bacterial Infections: In some cases, healthcare providers may prescribe Benzathine Penicillin for other bacterial infections when penicillin is the preferred treatment option.

Benzathine Penicillin is administered by intramuscular injection, which means it is injected into a muscle. The drug is slowly released from the injection site over an extended period, allowing for a more prolonged therapeutic effect. The specific dosage and duration of treatment will depend on the type and severity of the infection, as well as individual patient factors. Benzathine Penicillin under the guidance of a healthcare professional, as they will determine the appropriate dosage and treatment regimen based on your specific condition. Additionally, it’s crucial to complete the full course of treatment even if you start feeling better to ensure that the infection is completely eradicated.

How does Benzathine Penicillin Injection Work?

Benzathine Penicillin Injection works as an antibiotic to treat bacterial infections. It contains a form of penicillin known as benzathine penicillin G. Here’s how it works:

  • Interference with Bacterial Cell Wall Synthesis: Benzathine penicillin G interferes with the synthesis of bacterial cell walls. Bacterial cells have a protective outer layer called the cell wall, which maintains their structural integrity. This cell wall is composed of peptidoglycan, a complex molecule that provides strength to the bacterial cell.
  • Weakening of the Cell Wall: Benzathine penicillin G inhibits the formation of new peptidoglycan cross-links in the bacterial cell wall. This disruption weakens the cell wall’s structure and integrity.
  • Cell Lysis: As a result of the weakened cell wall, the bacterial cell becomes more vulnerable to the internal pressure created by its own cellular processes. This increased pressure can cause the bacterial cell to rupture or lyse.
  • Bacterial Death: When the bacterial cell wall is compromised, essential cellular components leak out, and the bacterial cell cannot survive. This leads to the death of the bacteria.
  • Resolution of Infection: By targeting and destroying the bacteria responsible for the infection, Benzathine Penicillin Injection helps the body’s immune system effectively clear the infection.

Benzathine Penicillin is particularly useful for treating certain bacterial infections, including syphilis and streptococcal infections. It is administered via intramuscular injection, allowing for a slow and sustained release of the medication into the bloodstream. This sustained release ensures that therapeutic levels of penicillin are maintained over an extended period, providing an effective treatment for bacterial infections. Benzathine Penicillin is only effective against bacterial infections and is not effective against viral infections like the common cold or flu. Additionally, the use of antibiotics should always be guided by a healthcare professional to ensure the correct diagnosis and appropriate treatment.

Benefits and Side effects of Benzathine Penicillin Injection?

Benzathine Penicillin Injection, like any medication, has benefits in treating bacterial infections, but it can also have potential side effects. It’s essential to use this medication under the guidance of a healthcare professional who can assess the potential benefits and risks for your specific medical condition. Here are the benefits and potential side effects of Benzathine Penicillin Injection:

Benefits:

  • Effective Treatment of Bacterial Infections: Benzathine Penicillin is highly effective against a range of bacterial infections. It can be used to treat conditions such as syphilis, streptococcal infections, and certain other bacterial diseases.
  • Prevention of Recurrent Rheumatic Fever: It is used as a prophylactic treatment to prevent the recurrence of rheumatic fever and to prevent the development of rheumatic heart disease in individuals with a history of acute rheumatic fever.
  • Treatment of Congenital Syphilis: Benzathine Penicillin can be used to treat syphilis in pregnant women to prevent transmission of the infection to the unborn baby (congenital syphilis).
  • Long-Lasting Action: One of the unique advantages of Benzathine Penicillin is its slow and sustained release from the injection site, which allows for an extended duration of action, reducing the need for frequent dosing.

Potential Side Effects:

  • Pain at Injection Site: Pain, redness, and swelling at the injection site are common side effects of Benzathine Penicillin. These symptoms are usually mild and temporary.
  • Allergic Reactions: Allergic reactions to penicillin antibiotics, including Benzathine Penicillin, can occur. These reactions may range from mild skin rashes to severe allergic reactions like anaphylaxis, which can be life-threatening.
  • Gastrointestinal Disturbances: Some individuals may experience nausea, vomiting, diarrhea, or abdominal pain as side effects.
  • Hypersensitivity Reactions: In rare cases, hypersensitivity reactions, including serum sickness-like reactions, may occur.
  • Neurologic Side Effects: High doses of Benzathine Penicillin have been associated with neurologic side effects, particularly in individuals with a history of neurosyphilis. These effects can include headache, seizures, and other neurological symptoms.
  • Jarisch-Herxheimer Reaction: After treatment for syphilis, a Jarisch-Herxheimer reaction can occur, which is a temporary worsening of symptoms due to the release of toxins from dying bacteria.
  • Antibiotic Resistance: Overuse or misuse of antibiotics can contribute to antibiotic resistance, which can make future infections more challenging to treat.

It’s essential to inform your healthcare provider of any allergies or previous adverse reactions to antibiotics before receiving Benzathine Penicillin Injection. If you experience severe allergic reactions or unusual symptoms after receiving the injection, seek immediate medical attention.

Frequently asked questions (FAQs) about Benzathine Penicillin Injection:

  1. What is Benzathine Penicillin Injection used for?

Benzathine Penicillin Injection is primarily used to treat bacterial infections caused by susceptible organisms. It is commonly used for the treatment of syphilis, streptococcal infections, and prevention of rheumatic fever.

  1. How is Benzathine Penicillin Injection administered?

It is typically administered by intramuscular injection, which means it is injected into a muscle, allowing for slow and sustained release of the medication.

  1. What is the recommended dosage and frequency of Benzathine Penicillin Injection?

The dosage and frequency of administration depend on the specific medical condition being treated, the severity of the infection, and individual patient factors. Your healthcare provider will determine the appropriate dosage and schedule.

  1. How long does Benzathine Penicillin stay in the body after injection?

Benzathine Penicillin has a slow and sustained release from the injection site, providing therapeutic levels for an extended period. The duration of action can vary, but a single injection can provide protection for several days to weeks.

  1. What are the common side effects of Benzathine Penicillin Injection?

Common side effects include pain, redness, and swelling at the injection site. Allergic reactions and gastrointestinal disturbances are possible but less common.

  1. Can I receive Benzathine Penicillin if I’m allergic to penicillin?

Individuals with a known allergy to penicillin should not receive Benzathine Penicillin, as they are at risk of severe allergic reactions. An alternative antibiotic will be prescribed.

  1. Is Benzathine Penicillin safe during pregnancy and breastfeeding?

Benzathine Penicillin is generally considered safe for use during pregnancy and breastfeeding, especially for the treatment of syphilis. However, it’s essential to discuss its use with a healthcare provider.

  1. Can Benzathine Penicillin interact with other medications or supplements?

It’s essential to inform your healthcare provider about all medications and supplements you are taking, as some drugs may interact with Benzathine Penicillin.

  1. Can I drink alcohol while receiving Benzathine Penicillin?

Moderate alcohol consumption is generally considered safe while receiving Benzathine Penicillin. However, it’s essential to follow your healthcare provider’s guidance, as alcohol may interact with certain medications.

  1. Can I stop taking Benzathine Penicillin once my symptoms improve?

No, it’s crucial to complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve. Stopping treatment prematurely can lead to incomplete eradication of the infection.

As Benzathine Penicillin Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Benzathine Penicillin Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Benzathine Penicillin Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Benzathine Penicillin Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

GENERIC NAME OF THE MEDICINAL PRODUCT:

(A) Benzathine Penicillin Injection BP 2.4MIU
(B) Benzathine Penicillin Injection BP 1.2MIU
(C) Benzathine Penicillin Injection BP 0.6 MIU

QUALITATIVE AND QUANTITATIVE COMPOSITION:

1. Benzathine Penicillin Injection 2.4MIU
a) Each vial contains:
Benzathine Benzylpenicillin BP………. 24,00,000 units.
Buffering Agent:
Sodium Citrate BP
Dispersing Agent:
Sodium Carboxymethyl Cellulose USP
b) Sterile Water for Injection BP……….10ml

2. Benzathine Penicillin Injection 1.2MIU
a) Each vial contains:
Benzathine Benzylpenicillin BP………. 1,200,000 units.
Buffering Agent:
Sodium Citrate BP
Dispersing Agent:
Sodium Carboxymethyl Cellulose USP
b) Sterile Water for Injection BP……….10ml


3. Benzathine Penicillin Injection 0.6MIU
a) Each vial contains:
Benzathine Benzylpenicillin BP………. 6,00,000 units.
Buffering Agent:
Sodium Citrate BP
Dispersing Agent:
Sodium Carboxymethyl Cellulose USP
b) Sterile Water for Injection BP……….10ml

THERAPEUTIC INDICATIONS:

Benzathine benzylpenicillin, also known as benzathine penicillin G, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically, it is to treat strep throat, diphtheria, syphilis, and yaws. It is also used to prevent rheumatic fever. It is given by injection into a muscle.

DIRECTION OF USE:

Add 3-4 ml water for Injection before use.
The prepared solution should be used immediately.
Any unused reconstitution portion must be discarded.
For dosage, administration and detailed direction of use, see pack insert.

CAUTION & WARNING:

CAUTION: Do not use the injection if the contents are not clear or contains visible particulate matter after reconstitution.
"Penicillin Sensitivity Test Essential"
Not to be infuse directly: Dilute the preparation with compatible intravenous solution prior to administration.
For deep intramuscular injection only
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
WARNING: To be sold by the retail on the prescription of a Registered Medical Practitioner only.
WARNING: If any particle is visible after dissolving the contents do not use & return for replacement.

STORAGE & DOSAGE:

Storage: Store below 25°C.
Protect from light & moisture.
Do not freeze.
KEEP OUT OF REACH OF CHILDREN
Dosage: As directed by Physician