Amoxicillin & Potassium Clavulanate Tablets IP 625mg Technical Specification:

Product Name:Amoxicillin & Potassium Clavulanate Tablets IP 625mg
Brand Name:Clavuxan
Strength:625mg, 375mg, 1gm
Dosage Form:Tablets (film-coated)
Route of Administration:Via Oral Route
Packing:10s, 30s, 100s, 500s
Pack Insert/Leaflet:PIL (Patient Information Leaflet)
Documents:COA, MOA, Stability Studies, GMP
Therapeutic use:β-lactam Antibiotic, Anti-bacterial & Penicillin
Indication: Amoxicillin/clavulanic acid is a combination of penicillin-type antibiotics used to treat a wide variety of bacterial infections.
Storage:Store protected from light & moisture at a temperature not exceeding 30 °C.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Amoxicillin & Potassium Clavulanate Tablets IP 625mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Amoxicillin & Potassium Clavulanate Tablets IP 625mg
    Each film-coated tablet contains:
    Amoxicillin Trihydrate IP
    equivalent to Amoxicillin              500mg
    Potassium Clavulanate IP (as Potassium Clavulanate Diluted IP)
    equivalent to Clavulanic Acid        125mg
    Colour: Titanium Dioxide IP

THERAPEUTIC INDICATIONS:

Amoxicillin/clavulanic acid is a combination of penicillin-type antibiotics used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. These antibiotic treats only bacterial infections.

CAUTION & SCHEDULE:

CAUTION: Read the enclosed leaflet before use.
Keep the medicine out of reach of children.
SWALLOW WHOLE DO NOT CHEW OR CRUSH

SCHEDULE: SCHEDULE H: NOT TO BE SOLD BY RETAIL WITHOUT THE PRESCRIPTION OF A registered medical practitioner.

STORAGE & DOSAGE:

Storage: Store protected from light & moisture at a temperature not exceeding 30 °C.
Dosage: As directed by the Physician

Why Taj Pharmaceuticals? 

Taj Pharmaceuticals stands as a trusted and reputable source for Amoxicillin and Potassium Clavulanate Tablets, offering a range of compelling reasons to choose their pharmaceutical products. With a rich legacy in the pharmaceutical industry, Taj Pharmaceuticals brings decades of experience and deep expertise to the forefront. This extensive knowledge ensures the consistent quality and effectiveness of medications like Amoxicillin and Potassium Clavulanate Tablets, instilling confidence in both healthcare providers and patients. One of the hallmarks of Taj Pharmaceuticals is its unwavering commitment to maintaining the highest standards of quality and safety in pharmaceutical products. Their manufacturing processes are marked by precision and rigorously enforced quality control measures. This commitment underscores their reputation as a pharmaceutical provider of choice.

Taj Pharmaceuticals operates as an exporter from India, playing a crucial role in making essential medications, including Amoxicillin and Potassium Clavulanate Tablets, accessible to healthcare providers and patients across the globe. Their extensive global distribution network ensures the availability of vital medications in various regions, contributing to improved healthcare on an international scale. Within its state-of-the-art pharmaceutical manufacturing facilities, Taj Pharmaceuticals leverages cutting-edge technology to produce accurate and consistent medications. These facilities serve as the backbone of their commitment to quality, as they strive to provide pharmaceutical products that meet the highest standards of reliability and safety. Taj Pharmaceuticals is driven by a patient-centric approach, placing the well-being of individuals at the forefront of their mission. By consistently delivering dependable medications like Amoxicillin and Potassium Clavulanate Tablets, they demonstrate a genuine dedication to improving patient health and enhancing overall quality of life.

What are Amoxycillin and Potassium Clavulanate Tablets and its uses:

Amoxicillin and Potassium Clavulanate Tablets is a combination medication used in the treatment of various bacterial infections. It contains two active ingredients: amoxicillin, which is a penicillin-type antibiotic, and potassium clavulanate, which is a betalactamase inhibitor. Here’s an overview of this medication and its common uses:

  • Medication Type: Amoxicillin and Potassium Clavulanate Tablets belongs to the class of antibiotics known as penicillin antibiotics. The addition of potassium clavulanate helps prevent the breakdown of amoxicillin by certain bacteria, enhancing its effectiveness.
  • Mechanism of Action:
    Amoxicillin:
    This component inhibits the growth of bacteria by interfering with the synthesis of their cell walls. It is effective against a wide range of bacterial species.
    Potassium Clavulanate: Potassium clavulanate works by inhibiting betalactamase enzymes produced by some bacteria. These enzymes can render antibiotics like amoxicillin ineffective. By inhibiting betalactamase, potassium clavulanate helps amoxicillin maintain its antibacterial activity.

Common Uses of Amoxicillin and Potassium Clavulanate Tablets:

  • Bacterial Infections: This medication is prescribed to treat various bacterial infections, including:
  • Respiratory Infections: Such as sinusitis, bronchitis, and pneumonia.
  • Ear Infections: Including otitis media (middle ear infection).
  • Urinary Tract Infections: Such as cystitis and pyelonephritis.
  • Skin and Soft Tissue Infections: Like cellulitis.
  • Dental Infections: Such as dental abscesses.
  • Bone Infections: In cases of osteomyelitis.
  • Mixed Infections: It is useful when the infection involves multiple types of bacteria or when the specific infecting organism is unknown.
  • Prevention of Postoperative Infections: In some surgical procedures, especially abdominal surgeries, Amoxicillin and Potassium Clavulanate Tablets may be administered before surgery to reduce the risk of postoperative infections.
  • Animal Bites: It is sometimes used in the treatment of animal bites, which can introduce a variety of bacteria into the body.
  • Chronic Obstructive Pulmonary Disease (COPD) Exacerbations: In patients with COPD, this medication can help manage exacerbations caused by bacterial infections.

How do Amoxicillin and Potassium Clavulanate Tabletss work?

Amoxicillin and Potassium Clavulanate Tablets work through the combined actions of its two active ingredients, amoxicillin and potassium clavulanate. Let’s delve into how each component functions:

  • Amoxicillin: Inhibition of Cell Wall Synthesis: Amoxicillin is a penicillin-type antibiotic that interferes with the synthesis of bacterial cell walls. Bacterial cells have a protective outer layer called the cell wall, which provides structural support. Amoxicillin targets the enzymes involved in building this cell wall, weakening it. As a result, bacterial cells become more susceptible to damage from osmotic pressure, ultimately leading to their rupture and death.
  • Potassium Clavulanate: Inhibition of Beta-Lactamase Enzymes: Many bacteria produce enzymes called beta-lactamases that can break down antibiotics like amoxicillin. This renders the antibiotics ineffective. Potassium clavulanate is a beta-lactamase inhibitor. It works by irreversibly binding to and inactivating these beta-lactamase enzymes. As a result, bacteria that produce beta-lactamases are no longer able to neutralize the amoxicillin component of the medication.

Combined Action:

  • The combination of amoxicillin and potassium clavulanate in this Tablets provides a dual mechanism of action:
  • Direct Bacterial Cell Wall Disruption: Amoxicillin targets the cell walls of susceptible bacteria, making it effective against a wide range of bacterial species.
  • Protection of Amoxicillin: Potassium clavulanate, by inhibiting beta-lactamases, protects amoxicillin from being broken down by bacterial enzymes. This ensures that amoxicillin can exert its antibacterial effect on a broader spectrum of bacteria, including those that would typically produce beta-lactamases to inactivate the antibiotic.

By working in tandem, amoxicillin, and potassium clavulanate effectively combat bacterial infections, making this combination medication particularly useful in cases where the specific infecting bacteria may be resistant to amoxicillin alone or in mixed infections involving multiple bacterial strains. It’s important to use this medication as directed by a healthcare provider to ensure its effectiveness and minimize the development of antibiotic resistance.

Benefits of Amoxicillin and Potassium Clavulanate Tablets:

  • Broad-Spectrum Antibiotic: This combination medication offers a broad spectrum of antibacterial coverage, making it effective against a wide range of bacterial infections.
  • Treatment of Mixed Infections: It is particularly useful in cases where the infection involves multiple types of bacteria or when the specific infecting organism is unknown.
  • Enhanced Efficacy: The inclusion of potassium clavulanate protects amoxicillin from being broken down by beta-lactamase enzymes produced by certain bacteria. This enhances the effectiveness of amoxicillin against bacteria that would otherwise render it ineffective.
  • Respiratory Infections: It is commonly used to treat respiratory infections such as sinusitis, bronchitis, and pneumonia, helping to alleviate symptoms and clear the infection.
  • Skin and Soft Tissue Infections: Amoxicillin and Potassium Clavulanate Tablets is effective in treating skin and soft tissue infections like cellulitis, reducing pain, swelling, and the spread of infection.
  • Urinary Tract Infections: It is commonly prescribed for urinary tract infections, providing relief from symptoms and eradicating the infection.
  • Dental Infections: In cases of dental abscesses, this medication can help control the infection and alleviate dental pain.

Common Side Effects of Amoxicillin and Potassium Clavulanate Tablets:

  • Gastrointestinal Disturbances: Common side effects include nausea, vomiting, diarrhea, and abdominal pain. Taking the Tablets with food can help reduce these effects.
  • Allergic Reactions: Although rare, some individuals may experience allergic reactions, which can manifest as skin rashes, itching, swelling, or difficulty breathing. Seek immediate medical attention if any signs of an allergic reaction occur.
  • Yeast Infections: The use of antibiotics like amoxicillin can sometimes lead to yeast infections, particularly in women. Symptoms may include vaginal itching and discharge.
  • Changes in Blood Tests: Amoxicillin and Potassium Clavulanate can affect certain blood tests, such as those measuring liver function. Inform your healthcare provider if you are undergoing blood tests while taking this medication.
  • Risk of Antibiotic Resistance: Prolonged or inappropriate use of antibiotics can contribute to the development of antibiotic-resistant bacteria. It’s essential to take this medication exactly as prescribed by a healthcare provider.
  • Other Side Effects: Less common side effects may include headache, dizziness, and changes in taste.

Frequently Asked Questions About Amoxicillin and Potassium Clavulanate Tablets:

Certainly, here are some frequently asked questions (FAQs) about Amoxicillin and Potassium Clavulanate Tablets:

  • What is Amoxicillin and Potassium Clavulanate Tablets used for?

Amoxicillin and Potassium Clavulanate Tablets is used to treat a wide range of bacterial infections, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, dental infections, and more.

  • How does Amoxicillin and Potassium Clavulanate Tablets work?

This medication combines amoxicillin, an antibiotic that inhibits bacterial cell wall synthesis, with potassium clavulanate, which prevents the breakdown of amoxicillin by certain bacteria. Together, they effectively combat bacterial infections.

  • Is this Tablets safe for children?

Amoxicillin and Potassium Clavulanate Tablets is prescribed to children when deemed necessary by a healthcare provider. Pediatric dosages are adjusted based on the child’s weight and the severity of the infection.

  • Can I take this Tablets if I’m pregnant or breastfeeding?

You should inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will consider the potential benefits and risks and determine whether this medication is appropriate for you.

  • How is the Tablets administered?

This Tablets is typically administered by a healthcare professional, such as a nurse or doctor, through an intravenous (IV) infusion. The dosage and infusion duration will be determined by your healthcare provider based on your condition.

  • Can I stop taking the Tablets when my symptoms improve?

It’s essential to complete the full course of treatment as prescribed, even if your symptoms improve before the medication is finished. Stopping prematurely can lead to incomplete eradication of the infection and potential antibiotic resistance.

  • Are there any dietary restrictions while taking this Tablets?

You can generally take this Tablets with or without food. However, taking it with food may help reduce gastrointestinal side effects like nausea and upset stomach.

  • What should I do if I miss a dose?

If you miss a dose, contact your healthcare provider for guidance. It’s important not to double the dose to make up for the missed one.

  • What are the common side effects of this Tablets?

Common side effects include gastrointestinal disturbances like nausea and diarrhea. Allergic reactions are rare but can occur. If you experience severe side effects or allergic reactions, seek immediate medical attention.

  • Can I drink alcohol while taking Amoxicillin and Potassium Clavulanate Tablets?

It is generally advisable to avoid alcohol while taking antibiotics as it can interfere with the effectiveness of the medication and may exacerbate certain side effects.

Patients should consult their healthcare provider for personalized information and guidance regarding the use of Amoxicillin and Potassium Clavulanate Tablets, as individual circumstances and medical guidelines may vary.

As Amoxicillin and Potassium Clavulanate Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Amoxicillin and Potassium Clavulanate Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Amoxicillin and Potassium Clavulanate Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Amoxicillin and Potassium Clavulanate Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

 

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Amoxycillin & Potassium Clavulanate Tablets IP 625mg
B) Amoxycillin & Potassium Clavulanate Tablets IP 375mg
C) Amoxycillin & Potassium Clavulanate Tablets IP 1gm

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Amoxycillin & Potassium Clavulanate Tablets IP 625mg
Each film-coated tablet contains:
Amoxycillin Trihydrate IP
equivalent to Amoxycillin 500mg
Potassium Clavulanate IP (as Potassium Clavulanate Diluted IP)
equivalent to Clavulanic Acid 125mg
Colour: Titanium Dioxide IP


B) Amoxycillin & Potassium Clavulanate Tablets IP 375mg
Each film-coated tablet contains:
Amoxycillin Trihydrate IP
equivalent to Amoxycillin 250 mg
Potassium Clavulanate IP (as Potassium Clavulanate Diluted IP)
equivalent to Clavulanic Acid 125 mg
Colour: Ferric oxide yellow

C) Amoxycillin & Potassium Clavulanate Tablets IP 1gm
Each film-coated tablet contains:
Amoxycillin Trihydrate IP
equivalent to Amoxycillin 875mg
Potassium Clavulanate IP (as Potassium Clavulanate Diluted IP)
equivalent to Clavulanic Acid 125mg
Colour: Ponceau 4 R

THERAPEUTIC INDICATIONS:

Amoxicillin/clavulanic acid is a combination penicillin-type antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. These antibiotic treats only bacterial infections.

CAUTION & SHEDULE:

CAUTION:
Read enclosed leaflet before use.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
SWALLOW WHOLE DO NOT CHEW OR CRUSH
SCHEDULE: SCHEDULE H: NOT TO BE SOLD BY RETAIL WITHOUT THE PRESCRIPTION OF A REGISTERED MEDICAL PRACTITIONER.

STORAGE & DOSAGE:

Storage: Store protected from light & moisture at a temperature not exceeding 30 °C.
Dosage: As directed by the Physician